Experiment set11IT088 for Pseudomonas putida KT2440

Compare to:

carbon source 2-Deoxy-D-glucose 100 mM

200 most detrimental genes:

  gene name fitness t score description  
PP_1824 +4.1 1.8 Smr domain protein compare
PP_1650 +3.8 32.8 Sensor protein GacS compare
PP_4099 +3.6 28.1 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1656 +3.3 16.9 ATP:GTP 3'-pyrophosphotransferase compare
PP_1655 +2.9 8.5 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_2889 +2.9 6.3 putative Transmembrane regulator PrtR compare
PP_4373 +2.8 14.0 Transcriptional regulator FleQ compare
PP_t11 +2.8 2.8 tRNA-Lys compare
PP_4171 +2.6 11.3 conserved exported protein of unknown function compare
PP_t29 +2.3 1.3 tRNA-Ala compare
PP_5225 +2.3 1.7 frataxin compare
PP_2341 +2.3 2.3 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_0001 +2.3 1.3 probable chromosome-partitioning protein compare
PP_3409 +2.2 4.3 putative Cobalamin biosynthesis protein cobE compare
PP_2337 +2.2 1.4 aconitate isomerase compare
PP_1994 +2.1 2.3 tRNA pseudouridine (38-40)synthase compare
PP_3248 +2.1 2.1 Dyp-type peroxidase family protein compare
PP_4517 +2.0 2.1 conserved protein of unknown function compare
PP_2025 +2.0 2.8 Exonuclease SbcD compare
PP_1055 +2.0 1.8 Type II secretion pathway protein GspN compare
PP_2121 +1.9 2.4 putative Lipoprotein compare
PP_0086 +1.9 1.9 conserved protein of unknown function compare
PP_5324 +1.9 1.9 Response regulator compare
PP_1428 +1.8 2.1 Sigma factor AlgU negative regulatory protein compare
PP_2864 +1.8 3.0 conserved protein of unknown function compare
PP_2720 +1.7 1.8 conserved protein of unknown function compare
PP_1783 +1.7 1.0 dTDP-glucose pyrophosphorylase compare
PP_5483 +1.7 1.7 conserved protein of unknown function compare
PP_4199 +1.7 1.2 putative Lipoprotein compare
PP_1999 +1.7 1.3 membrane protein required for colicin V production compare
PP_2336 +1.7 0.8 aconitate hydratase 1 compare
PP_2880 +1.7 2.0 Transcriptional regulator, TetR family compare
PP_2210 +1.6 2.9 LysR family transcriptional regulator compare
PP_1113 +1.6 8.4 Pyridoxal-phosphate dependent enzyme family protein compare
PP_0574 +1.6 10.1 DNA-binding response regulator, LuxR family compare
PP_2429 +1.5 2.1 putative Membrane protein compare
PP_4836 +1.5 1.4 conserved exported protein of unknown function compare
PP_5338 +1.5 1.8 aspartate ammonia-lyase compare
PP_5267 +1.5 2.1 putative cytochrome c5 compare
PP_3831 +1.5 4.4 conserved protein of unknown function compare
PP_0833 +1.5 0.8 queuine tRNA-ribosyltransferase compare
PP_4122 +1.4 0.7 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_4129 +1.4 0.7 NADH:ubiquinone oxidoreductase, membrane subunit L compare
PP_1215 +1.4 0.6 Crossover junction endodeoxyribonuclease RuvC compare
PP_2000 +1.4 0.9 amidophosphoribosyl transferase compare
PP_4223 +1.4 1.5 diaminobutyrate-2-oxoglutarate transaminase compare
PP_3726 +1.4 1.9 Enoyl-CoA hydratase/isomerase family protein compare
PP_1629 +1.4 2.7 Protein RecA compare
PP_0273 +1.4 2.7 conserved protein of unknown function compare
PP_4124 +1.4 0.8 NADH-quinone oxidoreductase subunit G compare
PP_4532 +1.4 1.2 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_4874 +1.4 0.6 50S ribosomal protein L9 compare
PP_4799 +1.4 0.7 putative Muramoyltetrapeptide carboxypeptidase compare
PP_5145 +1.4 12.6 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0719 +1.4 0.7 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_1454 +1.4 2.5 conserved protein of unknown function compare
PP_2475 +1.4 3.1 Transcriptional regulator, TetR family compare
PP_5309 +1.3 0.7 oxidative and nitrosative stress transcriptional dual regulator compare
PP_2378 +1.3 2.1 Fe/S biogenesis protein NfuA compare
PP_0856 +1.3 0.9 conserved lipoprotein of unknown function compare
PP_4999 +1.3 0.7 dihydroorotase-like protein compare
PP_4710 +1.3 6.5 tRNA pseudouridine 55 synthase compare
PP_2999 +1.3 1.4 Glyoxalase family protein compare
PP_1353 +1.3 0.7 conserved membrane protein of unknown function compare
PP_5359 +1.3 1.2 CobW/P47K family protein compare
PP_0959 +1.3 1.0 phospholipid ABC transporter compare
PP_2253 +1.3 1.5 Transcriptional regulator, GntR family compare
PP_4131 +1.3 1.1 NADH-quinone oxidoreductase subunit N compare
PP_4121 +1.3 1.3 NADH-quinone oxidoreductase subunit C/D compare
PP_3614 +1.3 1.4 conserved membrane protein of unknown function compare
PP_4892 +1.2 3.8 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex compare
PP_1096 +1.2 1.6 putative electron transport complex protein compare
PP_5310 +1.2 2.8 junction-specific ATP-dependent DNA helicase compare
PP_0048 +1.2 1.3 conserved protein of unknown function compare
PP_5717 +1.2 1.6 conserved protein of unknown function compare
PP_0025 +1.2 1.6 hypothetical protein compare
PP_1734 +1.2 0.8 Probable septum site-determining protein MinC compare
PP_5028 +1.2 1.9 proline iminopeptidase compare
PP_2160 +1.2 2.0 NADPH-dependent 7-cyano-7-deazaguanine reductase compare
PP_4769 +1.2 2.3 conserved protein of unknown function compare
PP_5053 +1.2 3.9 Protein-export protein SecB compare
PP_3447 +1.2 0.9 conserved membrane protein of unknown function compare
PP_0628 +1.2 1.6 conserved protein of unknown function compare
PP_5201 +1.2 3.5 conserved protein of unknown function, UPF0149 family compare
PP_4386 +1.2 2.9 flagellar basal-body rod protein FlgF compare
PP_4100 +1.2 5.2 Transcriptional regulator, Cro/CI family compare
PP_4004 +1.1 1.0 DNA translocase FtsK compare
PP_1322 +1.1 1.3 putative Lipoprotein compare
PP_2462 +1.1 2.2 conserved protein of unknown function compare
PP_0195 +1.1 0.9 conserved protein of unknown function compare
PP_2028 +1.1 1.7 conserved protein of unknown function containing tetratricopeptide (TPR) domain repeat compare
PP_3018 +1.1 2.2 conserved protein of unknown function compare
PP_5522 +1.1 3.0 protein of unknown function compare
PP_1657 +1.1 3.3 modified nucleoside triphosphate pyrophosphohydrolase compare
PP_0962 +1.1 1.5 toluene-tolerance protein compare
PP_4895 +1.1 0.9 tRNA dimethylallyltransferase compare
PP_4910 +1.1 0.6 conserved protein of unknown function compare
PP_4313 +1.1 3.3 putative peptidylprolyl isomerase compare
PP_4390 +1.1 4.6 flagellar basal-body rod protein FlgC compare
PP_1826 +1.1 0.9 Hydrolase, isochorismatase family compare
PP_1733 +1.1 2.1 membrane ATPase of the MinC-MinD-MinE system compare
PP_4925 +1.1 2.1 conserved protein of unknown function compare
PP_0063 +1.1 1.3 putative Lipid A biosynthesis lauroyl acyltransferase compare
PP_0703 +1.1 3.0 putative Transmembrane sensor compare
PP_5157 +1.1 2.7 conserved exported protein of unknown function compare
PP_1742 +1.1 2.6 conserved inner membrane protein of unknown function compare
PP_1598 +1.1 2.5 regulatory intramembrane protein RIP zinc protease compare
PP_4611 +1.1 2.7 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_0804 +1.1 5.0 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_3770 +1.1 1.6 conserved protein of unknown function compare
PP_0725 +1.1 3.8 conserved hypothetical TPR repeat protein compare
PP_2737 +1.0 1.0 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_2313 +1.0 1.5 conserved membrane protein of unknown function compare
PP_4964 +1.0 1.8 D-erythrose 4-phosphate dehydrogenase compare
PP_4352 +1.0 6.4 flagellin export apparatus, substrate specificity protein compare
PP_4981 +1.0 0.9 polyisoprene-binding protein, acidic stress response factor compare
PP_1147 +1.0 1.8 conserved protein of unknown function compare
PP_4993 +1.0 2.1 Glutathione synthetase compare
PP_0691 +1.0 0.6 Glutamate 5-kinase compare
PP_2653 +1.0 2.0 Transcriptional regulator, Cro/CI family compare
PP_5429 +1.0 2.4 protein of unknown function compare
PP_0220 +1.0 2.4 methionine import ATP-binding protein metN2 compare
PP_3625 +1.0 4.0 Transporter, LysE family compare
PP_4120 +1.0 0.7 NADH-quinone oxidoreductase subunit B compare
PP_5543 +1.0 2.0 protein of unknown function compare
PP_4824 +1.0 3.5 Sensor histidine kinase/response regulator compare
PP_0150 +1.0 1.7 conserved exported protein of unknown function compare
PP_4384 +1.0 4.7 Flagellar L-ring protein compare
PP_1124 +1.0 1.7 conserved membrane protein of unknown function compare
PP_0355 +1.0 2.0 Response regulator compare
PP_2764 +1.0 2.4 FMN reductase (NADPH) compare
PP_0775 +1.0 1.8 conserved protein of unknown function compare
PP_1903 +1.0 2.3 putative phosphotyrosine-protein phosphatase compare
PP_5232 +1.0 0.7 conserved protein of unknown function compare
PP_5537 +1.0 2.8 conserved membrane protein of unknown function compare
PP_4804 +1.0 0.6 RlpA-like lipoprotein compare
PP_0938 +1.0 4.8 conserved protein of unknown function compare
PP_2402 +1.0 0.6 putative Sensor histidine kinase compare
PP_0633 +1.0 2.0 Type 4 fimbrial assembly protein PilC compare
PP_4938 +1.0 3.9 putative Glycosyl transferase compare
PP_2387 +1.0 1.2 conserved protein of unknown function compare
PP_4385 +1.0 3.2 flagellar basal-body rod protein FlgG compare
PP_4391 +1.0 3.3 flagellar basal-body rod protein FlgB compare
PP_4519 +1.0 5.1 Agglutination protein compare
PP_4662 +1.0 1.5 conserved protein of unknown function compare
PP_2675 +1.0 1.8 Cytochrome c-type protein compare
PP_4721 +1.0 3.6 conserved membrane protein of unknown function compare
PP_1445 +1.0 4.6 carbohydrate-selective porin compare
PP_0393 +0.9 0.9 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_2087 +0.9 1.3 CmpX protein compare
PP_1808 +0.9 1.0 glucose-6-phosphate isomerase compare
PP_4126 +0.9 0.6 NADH-quinone oxidoreductase subunit I compare
PP_4520 +0.9 1.6 conserved protein of unknown function compare
PP_3408 +0.9 2.0 cobalt transporter subunit A compare
PP_1527 +0.9 2.7 tRNA threonylcarbamoyladenosine dehydratase (t(6)A37 dehydratase) compare
PP_1214 +0.9 0.8 putative transcriptional regulatory protein compare
PP_4693 +0.9 1.4 RNA polymerase-binding transcription factor DksA compare
PP_5706 +0.9 0.6 Sec translocation complex - SecG subunit compare
PP_5094 +0.9 2.2 putative enzyme with PLP binding domain compare
PP_1774 +0.9 1.4 conserved exported protein of unknown function compare
PP_4880 +0.9 2.2 exoribonuclease R compare
PP_4370 +0.9 2.3 Flagellar hook-basal body complex protein FliE compare
PP_3238 +0.9 2.1 putative Transcriptional regulator PyrR compare
PP_1543 +0.9 2.8 conserved protein of unknown function compare
PP_3463 +0.9 3.5 phenylacetaldehyde dehydrogenase compare
PP_5311 +0.9 3.6 putative signal transduction protein compare
PP_3693 +0.9 2.1 putative Transcriptional regulator MvaT, P16 subunit compare
PP_1544 +0.9 2.6 conserved protein of unknown function compare
PP_5441 +0.9 1.5 protein of unknown function compare
PP_0805 +0.9 4.6 Outer membrane efflux protein compare
PP_5038 +0.9 2.5 conserved lipoprotein of unknown function compare
PP_5229 +0.9 1.7 conserved protein of unknown function compare
PP_5263 +0.9 2.4 GGDEF domain protein compare
PP_5146 +0.9 4.4 RNA pyrophosphohydrolase compare
PP_2223 +0.9 3.8 conserved protein of unknown function compare
PP_1466 +0.9 1.6 Long-chain acyl-CoA thioester hydrolase family protein compare
PP_4722 +0.9 2.2 Transcription elongation factor GreA compare
PP_3144 +0.9 3.4 L-serine dehydratase compare
PP_0630 +0.9 0.5 DNA gyrase inhibitor YacG compare
PP_2127 +0.9 2.2 Sensor histidine kinase compare
PP_0674 +0.9 5.2 ADP/ATP ratio sensor and inhibitor of translation compare
PP_0168 +0.9 6.5 putative surface adhesion protein compare
PP_2616 +0.9 2.3 conserved protein of unknown function compare
PP_1736 +0.9 1.1 conserved protein of unknown function compare
PP_1186 +0.9 0.9 two component system DNA-binding transcriptional dual regulator compare
PP_5144 +0.9 3.2 conserved protein of unknown function compare
PP_0532 +0.9 2.6 conserved exported protein of unknown function compare
PP_0750 +0.9 1.9 conserved protein of unknown function compare
PP_1834 +0.8 1.8 conserved protein of unknown function compare
PP_1571 +0.8 1.8 conserved protein of unknown function compare
PP_2442 +0.8 0.9 conserved protein of unknown function, DUF480 family compare
PP_3634 +0.8 2.4 putative acetyltransferase, GNAT family compare
PP_1176 +0.8 1.3 conserved protein of unknown function compare
PP_0167 +0.8 5.8 Toxin secretion ATP-binding protein compare
PP_3930 +0.8 0.9 conserved exported protein of unknown function compare
PP_5337 +0.8 2.1 LysR family transcriptional regulator compare
PP_2023 +0.8 2.3 Glutathione S-transferase family protein compare
PP_4787 +0.8 1.1 putative protein with nucleoside triphosphate hydrolase domain compare
PP_2189 +0.8 1.1 conserved protein of unknown function compare
PP_1813 +0.8 1.7 ComEA-related protein compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source 2-Deoxy-D-glucose in Pseudomonas putida KT2440

For carbon source 2-Deoxy-D-glucose across organisms