Experiment set11IT086 for Pseudomonas putida KT2440

Compare to:

carbon source 2-Deoxy-D-glucose 10 mM

200 most important genes:

  gene name fitness t score description  
PP_1110 -6.1 -4.2 serine acetyltransferase compare
PP_4890 -5.7 -3.9 ATP phosphoribosyltransferase regulatory subunit compare
PP_0787 -5.5 -3.8 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_3790 -5.3 -7.3 diaminopimelate epimerase compare
PP_4680 -5.1 -4.9 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1985 -5.1 -3.5 3-isopropylmalate dehydratase large subunit compare
PP_3511 -5.0 -6.0 Branched-chain-amino-acid aminotransferase compare
PP_5098 -5.0 -4.8 methionine biosynthesis protein MetW compare
PP_4678 -5.0 -8.9 Ketol-acid reductoisomerase compare
PP_1988 -4.9 -4.8 3-isopropylmalate dehydrogenase compare
PP_2388 -4.9 -5.8 Transporter, LysE family compare
PP_5104 -4.9 -4.8 thiazole synthase compare
PP_0422 -4.9 -4.7 Indole-3-glycerol phosphate synthase compare
PP_0293 -4.8 -2.8 Imidazole glycerol phosphate synthase subunit HisF compare
PP_5097 -4.7 -9.5 homoserine O-acetyltransferase compare
PP_5348 -4.6 -10.3 Transcriptional regulator, LysR family compare
PP_0420 -4.6 -9.8 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_0967 -4.5 -6.9 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0290 -4.5 -6.9 Imidazole glycerol phosphate synthase subunit HisH compare
PP_5347 -4.5 -7.5 pyruvate carboxylase subunit A compare
PP_1109 -4.5 -13.3 Transcriptional regulator, GntR family compare
PP_2168 -4.3 -6.5 Transaldolase compare
PP_0965 -4.3 -9.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_1111 -4.2 -7.5 putative Synthetase compare
PP_1348 -4.1 -6.5 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_0966 -4.1 -4.9 Histidinol dehydrogenase compare
PP_5155 -4.1 -5.3 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_2001 -4.1 -9.4 O-succinylhomoserine sulfhydrylase compare
PP_5303 -4.0 -3.9 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_1088 -4.0 -3.9 Argininosuccinate synthase compare
PP_0292 -4.0 -3.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_1995 -4.0 -3.8 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_4922 -4.0 -12.1 Phosphomethylpyrimidine synthase compare
PP_2646 -3.9 -3.2 conserved protein of unknown function compare
PP_3376 -3.9 -7.3 putative phosphonate dehydrogenase compare
PP_5289 -3.8 -2.6 Acetylglutamate kinase compare
PP_4679 -3.8 -2.6 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_0417 -3.7 -15.6 Anthranilate synthase component 1 compare
PP_2371 -3.7 -2.6 Sulphite reductase hemoprotein, beta subunit compare
PP_5346 -3.7 -8.1 pyruvate carboxylase subunit B compare
PP_2370 -3.5 -3.4 conserved protein of unknown function compare
PP_2645 -3.4 -9.8 magnesium transporter, ATP-dependent compare
PP_2433 -3.4 -3.0 conserved protein of unknown function compare
PP_1986 -3.4 -2.3 3-isopropylmalate dehydratase small subunit compare
PP_0421 -3.4 -8.6 Anthranilate phosphoribosyltransferase compare
PP_0291 -3.4 -4.6 conserved protein of unknown function compare
PP_0735 -3.3 -1.6 molybdopterin-synthase adenylyltransferase compare
PP_1233 -3.3 -3.2 sulfurtransferase compare
PP_5075 -3.3 -9.1 glutamate synthase (NADPH) beta subunit compare
PP_1231 -3.2 -4.3 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_5076 -3.1 -18.1 L-glutamate synthase(NADPH) alpha subunit compare
PP_5128 -3.1 -6.6 Dihydroxy-acid dehydratase compare
PP_1079 -3.1 -3.6 Ornithine carbamoyltransferase compare
PP_5185 -3.1 -3.0 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_3505 -3.1 -3.2 conserved protein of unknown function compare
PP_2327 -3.0 -3.6 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_3244 -2.9 -3.3 Magnesium transporter, MgtC family compare
PP_0082 -2.9 -2.0 tryptophan synthase alpha chain compare
PP_0362 -2.8 -11.2 Biotin synthase compare
PP_0289 -2.8 -5.1 Imidazoleglycerol-phosphate dehydratase compare
PP_4909 -2.8 -2.7 phosphoserine phosphatase compare
PP_4917 -2.7 -5.1 3',5'-cyclic-nucleotide phosphodiesterase compare
PP_5015 -2.7 -1.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_2348 -2.7 -5.3 Sensor histidine kinase compare
PP_4782 -2.7 -2.6 Phosphomethylpyrimidine kinase compare
PP_4684 -2.6 -4.6 conserved protein of unknown function with kinase-like domain compare
PP_1025 -2.6 -8.6 2-isopropylmalate synthase compare
PP_3245 -2.4 -1.1 conserved protein of unknown function compare
PP_3999 -2.3 -2.3 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_2903 -2.3 -1.5 peptidyl-prolyl cis-trans isomerase B (rotamase B) compare
PP_2714 -2.3 -6.1 Sensor histidine kinase compare
PP_2328 -2.2 -1.5 Phosphoadenosine phosphosulfate reductase compare
PP_2390 -2.1 -4.0 Transcriptional regulator, LysR family compare
PP_1304 -2.0 -7.7 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_1063 -1.9 -7.1 DNA-binding transcriptional regulator, homocysteine-binding compare
PP_4723 -1.9 -2.5 Carbamoyl-phosphate synthase large chain compare
PP_3052 -1.8 -1.9 conserved protein of unknown function compare
PP_5090 -1.8 -1.9 putative cell division protein compare
PP_5328 -1.7 -6.5 putative phosphate transport system permease protein compare
PP_0949 -1.7 -4.3 putative ATP-binding protein UPF0042 compare
PP_3506 -1.7 -3.9 Magnesium chelatase, subunit ChII compare
PP_0834 -1.7 -1.4 Sec translocation complex subunit YajC compare
PP_4897 -1.7 -3.1 N-acetylmuramoyl-L-alanine amidase compare
PP_3312 -1.6 -1.5 putative Heat shock protein compare
PP_5168 -1.6 -2.4 sulfate/thiosulfate import ATP-binding protein compare
PP_1426 -1.6 -7.2 L-aspartate oxidase compare
PP_0910 -1.6 -4.6 conserved exported protein of unknown function compare
PP_1303 -1.6 -4.7 Sulfate adenylyltransferase subunit 2 compare
PP_2345 -1.5 -2.6 conserved exported protein of unknown function compare
PP_0513 -1.5 -1.7 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP compare
PP_5320 -1.5 -4.8 two-component system DNA-binding transcriptional dual response regulator PhoB compare
PP_5248 -1.5 -1.1 putative hydrolase compare
PP_1812 -1.5 -3.1 conserved protein of unknown function compare
PP_4937 -1.5 -2.7 toluene tolerance protein compare
PP_1632 -1.5 -1.4 conserved protein of unknown function compare
PP_3102 -1.5 -3.5 conserved protein of unknown function compare
PP_0366 -1.5 -3.3 dethiobiotin synthetase compare
PP_4961 -1.4 -0.6 putative Lipoprotein compare
PP_1051 -1.4 -3.0 Type II secretion pathway protein XcpV compare
PP_5571 -1.4 -1.8 conserved protein of unknown function compare
PP_0184 -1.4 -1.4 Argininosuccinate lyase compare
PP_2820 -1.4 -2.1 HTH-type transcriptional regulator nfxB compare
PP_4482 -1.4 -3.6 Transcriptional regulator, AraC family compare
PP_1122 -1.4 -1.7 OmpA family protein compare
PP_5014 -1.4 -0.9 Phosphoribosyl-AMP cyclohydrolase compare
PP_5628 -1.3 -2.3 conserved protein of unknown function compare
PP_5456 -1.3 -1.5 conserved protein of unknown function compare
PP_1054 -1.3 -2.0 Type II secretion pathway protein XcpZ compare
PP_0087 -1.3 -1.2 conserved exported protein of unknown function compare
PP_4364 -1.3 -5.3 putative Anti-sigma F factor antagonist compare
PP_4199 -1.3 -0.6 putative Lipoprotein compare
PP_5610 -1.3 -1.7 protein of unknown function compare
PP_4226 -1.3 -2.8 conserved protein of unknown function compare
PP_2137 -1.3 -1.9 beta-ketoadipyl CoA thiolase, beta component compare
PP_2217 -1.3 -3.2 enoyl-CoA hydratase compare
PP_5039 -1.3 -1.6 conserved protein of unknown function compare
PP_3824 -1.2 -2.9 conserved exported protein of unknown function compare
PP_2650 -1.2 -3.6 putative 4-hydroxybutyrate dehydrogenase compare
PP_4268 -1.2 -0.9 nucleoid-associated broad specificity regulator compare
PP_0506 -1.2 -6.4 putative ABC efflux transporter, permease protein compare
PP_0153 -1.2 -1.8 hypothetical protein compare
PP_4726 -1.2 -2.3 Chaperone protein DnaJ compare
PP_0377 -1.2 -1.5 coenzyme PQQ synthesis protein D compare
PP_1764 -1.2 -3.6 Phosphoglycolate phosphatase 2 compare
PP_1020 -1.2 -2.4 putative glucose-6-phosphate 1-epimerase compare
PP_0414 -1.2 -2.6 Polyamine ABC transporter, permease protein compare
PP_4952 -1.2 -1.2 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_5140 -1.2 -2.5 Transcriptional regulator, MerR family compare
PP_1310 -1.1 -1.4 conserved hypothetical protein compare
PP_2306 -1.1 -1.1 conserved exported protein of unknown function compare
PP_5448 -1.1 -2.9 conserved protein of unknown function compare
PP_3443 -1.1 -3.8 putative glyceraldehyde-3-phosphate dehydrogenase compare
PP_3417 -1.1 -4.0 D-gluconate transporter compare
PP_0893 -1.1 -2.5 ThiJ/PfpI family protein compare
PP_4994 -1.1 -2.8 conserved protein of unknown function compare
PP_5313 -1.1 -2.1 DNA-binding protein HU-alpha compare
PP_2496 -1.1 -2.2 conserved protein of unknown function compare
PP_4789 -1.1 -2.1 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_1328 -1.1 -1.3 Protein MraZ compare
PP_4695 -1.1 -5.6 Sensory box histidine kinase compare
PP_5176 -1.1 -2.9 conserved protein of unknown function compare
PP_1076 -1.1 -3.7 aquaglyceroporin compare
PP_1009 -1.1 -3.0 glyceraldehyde-3-phosphate dehydrogenase compare
PP_2002 -1.1 -1.6 putative enzyme compare
PP_1589 -1.1 -3.8 uridylyltransferase compare
PP_4060 -1.1 -6.0 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_3034 -1.0 -2.9 putative Regulator protein compare
PP_t57 -1.0 -2.5 tRNA-Arg compare
PP_2375 -1.0 -6.2 cobalamin-dependent methionine synthase compare
PP_0881 -1.0 -3.9 dipeptide ABC transporter - putative membrane subunit compare
PP_2537 -1.0 -3.4 conserved protein of unknown function compare
PP_0120 -1.0 -3.2 putative zinc ABC transporter compare
PP_4977 -1.0 -4.5 5,10-methylenetetrahydrofolate reductase compare
PP_4098 -1.0 -0.6 UvrABC system protein C compare
PP_2761 -1.0 -2.9 putative Ribose ABC transporter, permease protein compare
PP_3649 -1.0 -2.4 Transcriptional regulator, GntR family compare
PP_4317 -1.0 -1.3 conserved protein of unknown function compare
PP_2232 -1.0 -2.7 XRE family transcriptional regulator compare
PP_1864 -1.0 -2.3 conserved protein of unknown function compare
PP_4584 -1.0 -1.9 putative endonuclease compare
PP_2640 -1.0 -1.5 Acetyltransferase, GNAT family compare
PP_4818 -1.0 -2.8 ribosomal protein L11 methyltransferase compare
PP_0978 -1.0 -1.8 conserved protein of unknown function compare
PP_3449 -1.0 -1.7 conserved exported protein of unknown function compare
PP_2580 -1.0 -1.4 conserved protein of unknown function compare
PP_5035 -0.9 -3.3 Histidine utilization repressor compare
PP_1681 -0.9 -4.2 cobalamin 5'-phosphate synthase / Cobalamin synthase compare
PP_4518 -0.9 -3.1 conserved protein of unknown function compare
PP_1678 -0.9 -1.5 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase compare
PP_1176 -0.9 -1.2 conserved protein of unknown function compare
PP_5203 -0.9 -2.8 5-formyltetrahydrofolate cyclo-ligase compare
PP_5027 -0.9 -1.1 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_4980 -0.9 -3.0 ATP-dependent RNA helicase compare
PP_0878 -0.9 -2.8 dipeptide ABC transporter, binding subunit compare
PP_1662 -0.9 -3.1 conserved protein of unknown function compare
PP_5327 -0.9 -3.3 putative phosphate ABC transporter, permease subunit compare
PP_5644 -0.9 -1.4 conserved membrane protein of unknown function compare
PP_1224 -0.9 -3.4 periplasmic subunit of the TolQRA transport system compare
PP_5321 -0.9 -3.3 two-component system sensory histidine kinase compare
PP_3833 -0.9 -2.6 Response regulator compare
PP_3933 -0.9 -3.2 conserved membrane protein of unknown function compare
PP_0984 -0.9 -2.5 conserved membrane protein of unknown function compare
PP_2309 -0.9 -1.0 conserved protein of unknown function compare
PP_4701 -0.9 -0.7 glucose-6-phosphate isomerase compare
PP_5008 -0.9 -1.2 Poly granule-associated protein compare
PP_2307 -0.9 -1.3 conserved protein of unknown function compare
PP_1430 -0.9 -4.2 putative periplasmic serine endoprotease DegP-like compare
PP_1757 -0.9 -2.5 DNA-binding transcriptional dual regulator compare
PP_2883 -0.9 -0.7 conserved protein of unknown function compare
PP_4966 -0.9 -1.1 transcriptional regulator of methionine metabolism compare
PP_5475 -0.9 -1.0 conserved protein of unknown function compare
PP_3766 -0.9 -2.0 Lactoylglutathione lyase compare
PP_2510 -0.9 -1.5 conserved protein of unknown function compare
PP_3810 -0.9 -1.9 conserved protein of unknown function compare
PP_3776 -0.9 -3.9 putative permease (RarD protein) compare
PP_0879 -0.9 -2.6 dipeptide ABC transporter - putative ATP binding subunit compare
PP_1294 -0.9 -2.3 molybdopterin synthase large subunit compare
PP_0913 -0.9 -2.5 conserved exported protein of unknown function compare
PP_0127 -0.9 -2.7 Thiol:disulfide interchange protein compare
PP_2142 -0.9 -1.4 Cell division inhibitor SulA compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source 2-Deoxy-D-glucose in Pseudomonas putida KT2440

For carbon source 2-Deoxy-D-glucose across organisms