Experiment set11IT080 for Pseudomonas putida KT2440

Compare to:

pH 6

200 most important genes:

  gene name fitness t score description  
PP_5348 -5.1 -6.9 Transcriptional regulator, LysR family compare
PP_3511 -5.0 -3.4 Branched-chain-amino-acid aminotransferase compare
PP_0787 -4.9 -3.4 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_3790 -4.9 -6.7 diaminopimelate epimerase compare
PP_0290 -4.8 -3.3 Imidazole glycerol phosphate synthase subunit HisH compare
PP_4678 -4.8 -5.7 Ketol-acid reductoisomerase compare
PP_4890 -4.8 -4.6 ATP phosphoribosyltransferase regulatory subunit compare
PP_1985 -4.5 -3.1 3-isopropylmalate dehydratase large subunit compare
PP_3376 -4.5 -5.3 putative phosphonate dehydrogenase compare
PP_5346 -4.4 -4.3 pyruvate carboxylase subunit B compare
PP_5098 -4.4 -5.2 methionine biosynthesis protein MetW compare
PP_0967 -4.3 -4.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0422 -4.3 -4.2 Indole-3-glycerol phosphate synthase compare
PP_0293 -4.3 -2.2 Imidazole glycerol phosphate synthase subunit HisF compare
PP_0420 -4.2 -8.9 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_1988 -4.2 -5.7 3-isopropylmalate dehydrogenase compare
PP_4680 -4.1 -9.2 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5097 -4.1 -7.9 homoserine O-acetyltransferase compare
PP_2390 -4.1 -8.3 Transcriptional regulator, LysR family compare
PP_5104 -4.0 -5.4 thiazole synthase compare
PP_2001 -4.0 -7.5 O-succinylhomoserine sulfhydrylase compare
PP_0421 -3.9 -3.8 Anthranilate phosphoribosyltransferase compare
PP_0966 -3.9 -4.6 Histidinol dehydrogenase compare
PP_4922 -3.9 -10.8 Phosphomethylpyrimidine synthase compare
PP_2168 -3.8 -5.2 Transaldolase compare
PP_5155 -3.8 -3.7 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_0965 -3.7 -7.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_5128 -3.6 -9.0 Dihydroxy-acid dehydratase compare
PP_1109 -3.6 -10.2 Transcriptional regulator, GntR family compare
PP_1088 -3.5 -3.4 Argininosuccinate synthase compare
PP_1995 -3.5 -2.4 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_5347 -3.5 -9.4 pyruvate carboxylase subunit A compare
PP_2370 -3.5 -2.4 conserved protein of unknown function compare
PP_0417 -3.4 -14.0 Anthranilate synthase component 1 compare
PP_0362 -3.4 -11.5 Biotin synthase compare
PP_3312 -3.3 -1.3 putative Heat shock protein compare
PP_1111 -3.3 -6.7 putative Synthetase compare
PP_2903 -3.3 -2.1 peptidyl-prolyl cis-trans isomerase B (rotamase B) compare
PP_3244 -3.2 -2.2 Magnesium transporter, MgtC family compare
PP_4679 -3.2 -2.2 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_2645 -3.2 -8.6 magnesium transporter, ATP-dependent compare
PP_5303 -3.1 -4.6 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_5090 -3.1 -1.5 putative cell division protein compare
PP_0735 -3.0 -1.3 molybdopterin-synthase adenylyltransferase compare
PP_1110 -3.0 -3.7 serine acetyltransferase compare
PP_0292 -3.0 -3.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_5289 -2.9 -3.4 Acetylglutamate kinase compare
PP_1348 -2.9 -5.8 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_2371 -2.9 -3.4 Sulphite reductase hemoprotein, beta subunit compare
PP_5185 -2.9 -2.0 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_0289 -2.9 -6.3 Imidazoleglycerol-phosphate dehydratase compare
PP_1986 -2.9 -1.8 3-isopropylmalate dehydratase small subunit compare
PP_5110 -2.8 -1.7 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_3808 -2.8 -1.6 Antibiotic synthesis protein MbtH compare
PP_1231 -2.8 -3.3 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_1233 -2.7 -2.6 sulfurtransferase compare
PP_1011 -2.7 -8.2 glucokinase compare
PP_2820 -2.6 -2.6 HTH-type transcriptional regulator nfxB compare
PP_2327 -2.6 -1.8 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_1079 -2.6 -2.5 Ornithine carbamoyltransferase compare
PP_3505 -2.6 -1.8 conserved protein of unknown function compare
PP_5007 -2.6 -2.3 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_2388 -2.6 -2.2 Transporter, LysE family compare
PP_5076 -2.4 -12.9 L-glutamate synthase(NADPH) alpha subunit compare
PP_3052 -2.4 -1.7 conserved protein of unknown function compare
PP_4227 -2.4 -1.4 conserved protein of unknown function compare
PP_0901 -2.3 -3.6 DNA-binding response regulator compare
PP_5604 -2.3 -3.0 putative subtilisin-like serine protease compare
PP_5075 -2.3 -8.3 glutamate synthase (NADPH) beta subunit compare
PP_4684 -2.3 -2.7 conserved protein of unknown function with kinase-like domain compare
PP_1025 -2.3 -7.5 2-isopropylmalate synthase compare
PP_2631 -2.3 -0.9 putative cellulose biosynthesis, BcsF/YhjT compare
PP_0246 -2.3 -1.8 two-component system DNA-binding response transcriptional dual regulator compare
PP_1293 -2.3 -1.8 molybdopterin synthase small subunit compare
PP_4782 -2.3 -1.5 Phosphomethylpyrimidine kinase compare
PP_4909 -2.2 -1.5 phosphoserine phosphatase compare
PP_4701 -2.2 -0.9 glucose-6-phosphate isomerase compare
PP_3999 -2.2 -1.5 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_3328 -2.1 -2.2 putative Ring-cleaving dioxygenase compare
PP_0082 -2.1 -2.5 tryptophan synthase alpha chain compare
PP_2044 -2.1 -0.8 conserved inner membrane protein of unknown function compare
PP_1015 -2.1 -7.2 mannose/glucose ABC transporter, glucose-binding periplasmic protein compare
PP_3064 -2.1 -2.1 Phage tail protein compare
PP_0902 -2.1 -6.7 integral membrane sensor signal transduction histidine kinase compare
PP_2348 -2.1 -2.8 Sensor histidine kinase compare
PP_5015 -2.1 -1.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_5327 -2.1 -6.6 putative phosphate ABC transporter, permease subunit compare
PP_2681 -2.0 -0.8 coenzyme PQQ synthesis protein D compare
PP_2416 -2.0 -1.7 putative Iron ABC transporter, ATP-binding protein compare
PP_0506 -2.0 -9.5 putative ABC efflux transporter, permease protein compare
PP_3411 -1.9 -1.1 conserved protein of unknown function compare
PP_1020 -1.9 -2.9 putative glucose-6-phosphate 1-epimerase compare
PP_2646 -1.9 -2.0 conserved protein of unknown function compare
PP_5000 -1.9 -0.7 peptidase component of the ATP-dependent HslVU protease compare
PP_5017 -1.9 -0.8 Sec-independent protein translocase protein TatB compare
PP_5491 -1.9 -2.6 conserved protein of unknown function with SEC-C motif domain compare
PP_1426 -1.9 -7.5 L-aspartate oxidase compare
PP_4268 -1.9 -0.8 nucleoid-associated broad specificity regulator compare
PP_2060 -1.9 -1.5 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_5328 -1.8 -4.6 putative phosphate transport system permease protein compare
PP_2714 -1.8 -3.6 Sensor histidine kinase compare
PP_2345 -1.8 -2.0 conserved exported protein of unknown function compare
PP_4789 -1.7 -4.1 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_1017 -1.7 -5.0 mannose/glucose ABC transporter, permease protein compare
PP_t10 -1.7 -1.3 tRNA-Pro compare
PP_1016 -1.7 -5.1 mannose/glucose ABC transporter, permease protein compare
PP_5533 -1.7 -1.1 conserved protein of unknown function compare
PP_0957 -1.7 -1.5 D-arabinose 5-phosphate isomerase compare
PP_4593 -1.7 -1.0 conserved protein of unknown function compare
PP_5508 -1.6 -1.2 conserved protein of unknown function compare
PP_2414 -1.6 -1.7 conserved exported protein of unknown function compare
PP_0127 -1.6 -4.3 Thiol:disulfide interchange protein compare
PP_5313 -1.6 -1.5 DNA-binding protein HU-alpha compare
PP_3034 -1.5 -2.2 putative Regulator protein compare
PP_0291 -1.5 -2.4 conserved protein of unknown function compare
PP_0305 -1.5 -2.7 HTH-type transcriptional regulator CdhR compare
PP_5487 -1.5 -3.1 conserved protein of unknown function compare
PP_4897 -1.5 -2.5 N-acetylmuramoyl-L-alanine amidase compare
PP_2217 -1.5 -2.1 enoyl-CoA hydratase compare
PP_0878 -1.5 -3.5 dipeptide ABC transporter, binding subunit compare
PP_1122 -1.5 -1.4 OmpA family protein compare
PP_1310 -1.5 -1.7 conserved hypothetical protein compare
PP_2640 -1.5 -3.3 Acetyltransferase, GNAT family compare
PP_0366 -1.5 -3.9 dethiobiotin synthetase compare
PP_4482 -1.5 -3.3 Transcriptional regulator, AraC family compare
PP_4785 -1.5 -6.2 conserved exported protein of unknown function compare
PP_0022 -1.5 -0.8 hypothetical protein compare
PP_1410 -1.5 -0.7 conserved protein of unknown function compare
PP_3040 -1.4 -2.9 Pyocin R2_PP, holin compare
PP_4364 -1.4 -1.9 putative Anti-sigma F factor antagonist compare
PP_5571 -1.4 -1.5 conserved protein of unknown function compare
PP_4952 -1.4 -1.1 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_1845 -1.4 -3.0 Enoyl-CoA hydratase/isomerase family protein compare
PP_0435 -1.4 -8.3 Peptidase, M23/M37 family compare
PP_2503 -1.4 -1.6 putative 3-oxoacyl-(Acyl-carrier-protein) reductase compare
PP_1018 -1.4 -3.8 mannose/glucose ABC transporter - ATP binding subunit compare
PP_0120 -1.4 -3.3 putative zinc ABC transporter compare
PP_1224 -1.4 -3.4 periplasmic subunit of the TolQRA transport system compare
PP_1012 -1.3 -2.6 DNA-binding response regulator compare
PP_3245 -1.3 -0.6 conserved protein of unknown function compare
PP_5321 -1.3 -4.8 two-component system sensory histidine kinase compare
PP_4009 -1.3 -2.9 ATP-dependent Clp protease adapter protein ClpS compare
PP_4997 -1.3 -1.7 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_3035 -1.3 -1.4 conserved protein of unknown function compare
PP_5202 -1.3 -1.3 putative cell division protein compare
PP_2031 -1.3 -1.2 conserved protein of unknown function compare
PP_5320 -1.3 -4.3 two-component system DNA-binding transcriptional dual response regulator PhoB conserved
PP_5159 -1.3 -2.9 conserved protein of unknown function compare
PP_2328 -1.3 -2.2 Phosphoadenosine phosphosulfate reductase compare
PP_3924 -1.3 -1.7 conserved protein of unknown function compare
PP_1513 -1.3 -1.4 Ribosomal RNA small subunit methyltransferase J compare
PP_2433 -1.2 -0.7 conserved protein of unknown function compare
PP_1669 -1.2 -3.3 NLP/P60 family protein compare
PP_3532 -1.2 -1.5 Transcriptional regulator, AsnC family compare
PP_0377 -1.2 -1.2 coenzyme PQQ synthesis protein D compare
PP_1860 -1.2 -2.1 Organic hydroperoxide resistance transcriptional regulator compare
PP_2513 -1.2 -3.3 4-oxalomesaconate tautomerase compare
PP_2145 -1.2 -4.2 beta-N-acetylglucosaminidase compare
PP_2153 -1.2 -1.7 conserved protein of unknown function compare
PP_0434 -1.2 -5.7 Anhydro-N-acetylmuramic acid kinase compare
PP_2575 -1.2 -2.1 conserved exported protein of unknown function compare
PP_1352 -1.2 -2.2 UPF0234 protein PP_1352 compare
PP_5557 -1.2 -0.8 protein of unknown function compare
PP_0364 -1.2 -4.5 pimeloyl-[acp] methyl ester esterase compare
PP_4695 -1.2 -5.8 Sensory box histidine kinase compare
PP_3787 -1.2 -3.3 conserved protein of unknown function compare
PP_3365 -1.2 -0.8 Acetolactate synthase compare
PP_1825 -1.2 -1.6 conserved exported protein of unknown function compare
PP_2847 -1.2 -1.3 Urease accessory protein UreJ compare
PP_5382 -1.2 -3.3 putative exported protein compare
PP_3824 -1.2 -2.5 conserved exported protein of unknown function compare
PP_1898 -1.2 -1.1 MotA/TolQ/ExbB proton channel family protein compare
PP_2494 -1.1 -2.6 conserved protein of unknown function compare
PP_3508 -1.1 -1.6 Protein CobW compare
PP_1938 -1.1 -1.2 conserved protein of unknown function compare
PP_0184 -1.1 -0.8 Argininosuccinate lyase compare
PP_2582 -1.1 -2.1 putative Heme oxygenase compare
PP_2989 -1.1 -3.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
PP_3384 -1.1 -1.8 gluconate 2-dehydrogenase gamma subunit compare
PP_4060 -1.1 -5.7 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_3942 -1.1 -3.7 maleate isomerase compare
PP_1304 -1.1 -4.5 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_5140 -1.1 -1.9 Transcriptional regulator, MerR family compare
PP_2403 -1.1 -0.7 Chemotaxis protein CheY compare
PP_4238 -1.1 -1.3 conserved protein of unknown function compare
PP_4870 -1.1 -2.5 Azurin compare
PP_1054 -1.1 -1.6 Type II secretion pathway protein XcpZ compare
PP_5200 -1.1 -4.3 proline aminopeptidase P II compare
PP_1764 -1.1 -3.4 Phosphoglycolate phosphatase 2 compare
PP_1009 -1.1 -2.6 glyceraldehyde-3-phosphate dehydrogenase compare
PP_5514 -1.1 -3.0 conserved protein of unknown function compare
PP_2334 -1.0 -4.8 2-methylisocitrate lyase compare
PP_4136 -1.0 -0.9 Transcriptional regulator, LuxR family compare
PP_5241 -1.0 -1.7 DNA-binding response regulator, LuxR family compare
PP_0261 -1.0 -3.2 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_1512 -1.0 -1.3 conserved protein of unknown function compare
PP_5008 -1.0 -1.0 Poly granule-associated protein compare
PP_1063 -1.0 -3.6 DNA-binding transcriptional regulator, homocysteine-binding compare
PP_1731 -1.0 -1.6 23S rRNA (746) and tRNA (32) pseudouridine synthase compare
PP_1508 -1.0 -2.3 conserved protein of unknown function compare


Specific Phenotypes

For 5 genes in this experiment

For pH D-Glucose in Pseudomonas putida KT2440

For pH D-Glucose across organisms