Experiment set10S151 for Escherichia coli BL21

Compare to:

D-Glucose

200 most important genes:

  gene name fitness t score description  
ECD_01924 -8.0 -5.4 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase compare
ECD_02443 -7.6 -5.2 serine hydroxymethyltransferase compare
ECD_00911 -7.3 -10.0 3-phosphoserine/phosphohydroxythreonine aminotransferase compare
ECD_01926 -6.9 -4.7 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase compare
ECD_01258 -6.3 -3.7 orotidine-5'-phosphate decarboxylase compare
ECD_00004 -6.3 -8.6 L-threonine synthase compare
ECD_01235 -6.2 -4.3 tryptophan synthase, beta subunit compare
ECD_00003 -6.2 -7.9 homoserine kinase compare
ECD_02254 -6.1 -3.7 chorismate synthase compare
ECD_02744 -6.1 -17.2 D-3-phosphoglycerate dehydrogenase compare
ECD_00074 -6.0 -13.0 3-isopropylmalate dehydratase large subunit compare
ECD_00002 -5.9 -19.5 Bifunctional aspartokinase/homoserine dehydrogenase 1 compare
ECD_01922 -5.7 -4.9 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase compare
ECD_03652 -5.6 -18.0 ketol-acid reductoisomerase, NAD(P)-binding compare
ECD_04264 -5.4 -7.3 3-phosphoserine phosphatase compare
ECD_02607 -5.4 -2.9 phosphoadenosine phosphosulfate reductase; PAPS reductase, thioredoxin dependent compare
ECD_03132 -5.4 -3.3 dehydroshikimate reductase, NAD(P)-binding compare
ECD_03649 -4.9 -15.3 dihydroxyacid dehydratase compare
ECD_00053 -4.9 -6.4 diadenosine tetraphosphatase compare
ECD_00912 -4.9 -6.7 5-enolpyruvylshikimate-3-phosphate synthetase compare
ECD_01925 -4.9 -3.3 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
ECD_00075 -4.8 -11.7 3-isopropylmalate dehydrogenase, NAD(+)-dependent compare
ECD_00073 -4.5 -4.3 3-isopropylmalate dehydratase small subunit compare
ECD_01234 -4.5 -1.9 tryptophan synthase, alpha subunit compare
ECD_03707 -4.5 -11.3 methionine biosynthesis regulon transcriptional regulator compare
ECD_02686 -4.3 -17.4 diaminopimelate decarboxylase, PLP-binding compare
ECD_00240 -4.1 -11.1 gamma-glutamylphosphate reductase compare
ECD_03827 -4.1 -13.9 5,10-methylenetetrahydrofolate reductase compare
ECD_04086 -4.0 -6.2 3'(2'),5'-bisphosphate nucleotidase compare
ECD_02489 -4.0 -16.0 fused chorismate mutase T/prephenate dehydrogenase compare
ECD_00333 -4.0 -5.3 pyrroline-5-carboxylate reductase, NAD(P)-binding compare
ECD_02488 -3.9 -6.9 chorismate mutase and prephenate dehydratase, P-protein compare
ECD_03708 -3.9 -17.3 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase compare
ECD_03883 -3.8 -11.7 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase compare
ECD_01923 -3.7 -4.4 histidinol-phosphate aminotransferase compare
ECD_00473 -3.6 -4.2 N5-carboxyaminoimidazole ribonucleotide mutase compare
ECD_00076 -3.6 -8.1 2-isopropylmalate synthase compare
ECD_02449 -3.4 -13.2 phosphoribosylformyl-glycineamide synthetase compare
ECD_03648 -3.4 -12.6 branched-chain amino acid aminotransferase compare
ECD_00056 -3.4 -7.6 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent compare
ECD_02881 -3.3 -10.7 cystathionine beta-lyase, PLP-dependent compare
ECD_03797 -3.3 -6.7 sensory histidine kinase in two-component regulatory system with CpxR compare
ECD_01058 -3.3 -3.1 dihydro-orotase compare
ECD_03241 -3.2 -6.3 3-dehydroquinate synthase compare
ECD_01238 -3.2 -5.2 component I of anthranilate synthase compare
ECD_02391 -3.0 -6.9 phosphoribosylaminoimidazole synthetase compare
ECD_03882 -3.0 -9.1 phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase compare
ECD_01236 -2.9 -7.8 indole-3-glycerolphosphate synthetase and N-(5-phosphoribosyl)anthranilate isomerase compare
ECD_02399 -2.9 -4.2 GMP synthetase (glutamine aminotransferase) compare
ECD_03825 -2.9 -8.8 cystathionine gamma-synthase, PLP-dependent compare
ECD_03038 -2.8 -10.2 argininosuccinate synthetase compare
ECD_03650 -2.8 -11.4 l-threonine dehydratase, biosynthetic; also known as threonine deaminase compare
ECD_00239 -2.7 -5.9 gamma-glutamate kinase compare
ECD_02629 -2.7 -12.0 (p)ppGpp synthetase I/GTP pyrophosphokinase compare
ECD_03845 -2.7 -11.7 argininosuccinate lyase compare
ECD_03219 -2.7 -5.3 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase compare
ECD_02400 -2.6 -6.7 IMP dehydrogenase compare
ECD_03897 -2.6 -6.7 glucosephosphate isomerase compare
ECD_01237 -2.6 -5.4 fused glutamine amidotransferase (component II) of anthranilate synthase/anthranilate phosphoribosyl transferase compare
ECD_03499 -2.6 -8.6 orotate phosphoribosyltransferase compare
ECD_03731 -2.4 -4.0 TatABCE protein translocation system subunit compare
ECD_02237 -2.4 -7.6 amidophosphoribosyltransferase compare
ECD_02245 -2.4 -4.5 erythronate-4-phosphate dehydrogenase compare
ECD_03755 -2.3 -6.0 glutamine synthetase compare
ECD_02600 -2.3 -10.0 adenosine 5'-phosphosulfate kinase compare
ECD_02507 -2.3 -1.8 toxic UPF0083 family protein inhibitor of 70S ribosome formation compare
ECD_03844 -2.2 -8.6 acetylglutamate kinase compare
ECD_04120 -2.2 -10.3 ornithine carbamoyltransferase 1 compare
ECD_03842 -2.2 -12.3 acetylornithine deacetylase compare
ECD_00472 -2.2 -4.6 N5-carboxyaminoimidazole ribonucleotide synthase compare
ECD_03885 -2.1 -8.2 homoserine O-transsuccinylase compare
ECD_02857 -2.1 -1.7 hypothetical protein compare
ECD_02726 -2.1 -5.5 site-specific tyrosine recombinase compare
ECD_04113 -2.1 -6.5 aspartate carbamoyltransferase, catalytic subunit compare
ECD_00949 -2.1 -3.0 dihydro-orotate oxidase, FMN-linked compare
ECD_00893 -2.0 -7.1 leucine-responsive global transcriptional regulator compare
ECD_00037 -2.0 -9.1 carbamoyl-phosphate synthase large subunit compare
ECD_02609 -2.0 -6.8 sulfite reductase, alpha subunit, flavoprotein compare
ECD_02666 -2.0 -10.4 amino acid N-acetyltransferase and inactive acetylglutamate kinase compare
ECD_03843 -1.9 -10.0 N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding compare
ECD_00680 -1.9 -4.9 citrate synthase compare
ECD_03841 -1.9 -9.7 phosphoenolpyruvate carboxylase compare
ECD_01928 -1.9 -2.0 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase compare
ECD_03687 -1.9 -3.1 site-specific tyrosine recombinase compare
ECD_03093 -1.9 -3.3 DUF1043 family inner membrane-anchored protein compare
ECD_00036 -1.9 -5.9 carbamoyl phosphate synthetase small subunit, glutamine amidotransferase compare
ECD_t00077 -1.8 -1.4 tRNA-Thr compare
ECD_01575 -1.8 -2.7 dihydromonapterin reductase, NADPH-dependent; dihydrofolate reductase isozyme compare
ECD_02314 -1.8 -5.9 cysteine synthase A, O-acetylserine sulfhydrolase A subunit compare
ECD_03651 -1.7 -6.3 transcriptional activator of ilvC; autorepressor compare
ECD_03801 -1.7 -6.5 6-phosphofructokinase I compare
ECD_00109 -1.6 -7.2 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; murein amidase compare
ECD_00432 -1.6 -2.0 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase compare
ECD_02608 -1.6 -6.7 sulfite reductase, beta subunit, NAD(P)-binding, heme-binding compare
ECD_03625 -1.5 -3.8 5-methylaminomethyl-2-thiouridine modification at tRNA U34 compare
ECD_01444 -1.5 -2.1 D,D-dipeptide ABC transporter permease compare
ECD_02393 -1.5 -3.9 polyphosphate kinase, component of RNA degradosome compare
ECD_02602 -1.5 -7.5 sulfate adenylyltransferase, subunit 2 conserved
ECD_03238 -1.4 -2.6 D-ribulose-5-phosphate 3-epimerase compare
ECD_02238 -1.4 -1.6 colicin V production protein compare
ECD_03257 -1.4 -2.2 response regulator in two-component regulatory system with EnvZ compare
ECD_02765 -1.4 -3.6 transketolase 1, thiamine triphosphate-binding compare
ECD_03078 -1.4 -7.1 glutamate synthase, 4Fe-4S protein, small subunit compare
ECD_02601 -1.3 -6.0 sulfate adenylyltransferase, subunit 1 conserved
ECD_01828 -1.3 -3.2 zinc ABC transporter periplasmic binding protein compare
ECD_00160 -1.3 -8.0 serine endoprotease (protease Do), membrane-associated compare
ECD_03646 -1.3 -9.2 acetolactate synthase II, valine insensitive, large subunit compare
ECD_00807 -1.3 -1.2 deoxyribose-5-phosphate-inducible deoxyribose operon transcriptional repressor; repressor of nupG and tsx compare
ECD_00388 -1.3 -4.7 proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases compare
ECD_01101 -1.3 -2.1 OM lipoprotein stimulator of MrcB transpeptidase compare
ECD_00703 -1.2 -4.0 quinolinate synthase, subunit A compare
ECD_03097 -1.2 -3.3 l-arginine-responsive arginine metabolism regulon transcriptional regulator compare
ECD_01793 -1.2 -2.8 stress protein, member of the CspA-family compare
ECD_02220 -1.2 -1.1 UPF0208 family inner membrane protein compare
ECD_03890 -1.2 -5.1 transcriptional repressor compare
ECD_00423 -1.1 -2.9 gap repair protein compare
ECD_01492 -1.1 -3.2 cysteine and O-acetyl-L-serine efflux system compare
ECD_04111 -1.1 -3.1 enamine/imine deaminase, reaction intermediate detoxification compare
ECD_00384 -1.1 -7.0 muropeptide transporter compare
ECD_02687 -1.1 -6.4 transcriptional activator of lysA; autorepressor compare
ECD_00569 -1.1 -2.2 Spo0J family protein, ParB-like nuclease domain compare
ECD_00112 -1.1 -4.8 pyruvate dehydrogenase complex repressor; autorepressor compare
ECD_03077 -1.1 -8.3 glutamate synthase, large subunit compare
ECD_00682 -1.1 -3.0 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_02463 -1.1 -2.9 back-translocating elongation factor EF4, GTPase compare
ECD_01571 -1.1 -2.2 pyridine nucleotide transhydrogenase, beta subunit compare
ECD_03498 -1.1 -4.4 nucleoid occlusion factor, anti-FtsZ division inhibitor compare
ECD_03242 -1.0 -1.3 shikimate kinase I compare
ECD_04107 -1.0 -1.7 trehalose-6-P hydrolase compare
ECD_00681 -1.0 -1.6 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_00683 -1.0 -3.6 succinate dehydrogenase, flavoprotein subunit compare
ECD_02500 -1.0 -6.5 cytochrome c assembly protein family inner membrane protein compare
ECD_00014 -1.0 -2.0 chaperone Hsp70, with co-chaperone DnaJ compare
ECD_01172 -1.0 -1.2 periplasmic trehalase compare
ECD_03647 -1.0 -2.9 acetolactate synthase 2 small subunit compare
ECD_01794 -1.0 -5.2 DUF2527 family heat-induced protein compare
ECD_01167 -1.0 -1.2 murein tetrapeptide carboxypeptidase; LD-carboxypeptidase A compare
ECD_03005 -1.0 -1.4 N-acetylgalactosamine-specific enzyme IIB component of PTS compare
ECD_03067 -1.0 -1.0 RNA polymerase, sigma 54 (sigma N) factor compare
ECD_01195 -1.0 -1.1 cation transport regulator compare
ECD_00407 -0.9 -1.3 DUF1428 family protein compare
ECD_02792 -0.9 -1.7 oxidative damage protective factor for iron-sulfur proteins compare
ECD_00148 -0.9 -5.2 fused glycosyl transferase and transpeptidase compare
ECD_01866 -0.9 -3.1 trehalose-6-phosphate phosphatase, biosynthetic compare
ECD_01211 -0.9 -2.2 PcnB-degradosome interaction factor; response regulator compare
ECD_02324 -0.9 -1.9 sulfate/thiosulfate ABC transporter permease compare
ECD_02525 -0.9 -1.8 DNA binding protein, nucleoid-associated compare
ECD_00335 -0.9 -2.7 shikimate kinase II compare
ECD_01784 -0.9 -3.5 L-serine dehydratase 1 compare
ECD_02167 -0.9 -2.7 anaerobic sn-glycerol-3-phosphate dehydrogenase, large FAD/NAD(P)-binding subunit compare
ECD_00389 -0.9 -3.6 ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease compare
ECD_03240 -0.9 -6.1 cell division protein that binds to the septal ring compare
ECD_02122 -0.9 -1.2 periplasmic thioredoxin of cytochrome c-type biogenesis compare
ECD_02297 -0.9 -1.2 putative enzyme IIB component of PTS compare
ECD_01459 -0.9 -2.2 putative oxidoreductase compare
ECD_01220 -0.9 -3.3 oligopeptide ABC transporter ATPase compare
ECD_01957 -0.9 -1.6 GDP-mannose mannosyl hydrolase compare
ECD_01370 -0.9 -1.7 aldehyde dehydrogenase A, NAD-linked compare
ECD_01800 -0.9 -2.3 putative endopeptidase compare
ECD_01624 -0.8 -1.5 glutaredoxin-4 compare
ECD_t00019 -0.8 -1.0 tRNA-Lys compare
ECD_00513 -0.8 -1.8 hypothetical protein compare
ECD_03583 -0.8 -4.9 gap repair protein compare
ECD_03555 -0.8 -4.6 acetolactate synthase 2 large subunit compare
ECD_03869 -0.8 -4.3 adenylyltransferase, modifies ThiS C-terminus compare
ECD_04373 -0.8 -1.7 UV-inducible membrane toxin, DinQ-AgrB type I toxin-antitoxin system compare
ECD_00813 -0.8 -1.3 transcriptional regulator of csgD and ybiJI; autoregulator compare
ECD_00554 -0.8 -1.9 regulator of length of O-antigen component of lipopolysaccharide chains compare
ECD_00378 -0.8 -1.3 hypothetical protein compare
ECD_01210 -0.8 -1.3 putative patatin-like family phospholipase compare
ECD_02155 -0.8 -1.5 DUF1175 family protein, putative host defense protein compare
ECD_03507 -0.8 -2.6 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase compare
ECD_02373 -0.8 -1.7 hydrogenase 4, 4Fe-4S subunit compare
ECD_02459 -0.8 -1.2 gap repair protein compare
ECD_00834 -0.8 -1.5 putative capsid scaffolding protein compare
ECD_t00083 -0.8 -1.0 tRNA-Leu compare
ECD_01263 -0.8 -2.5 ribonuclease II compare
ECD_00925 -0.7 -1.1 putative S-adenosyl-L-methionine-dependent methyltransferase compare
ECD_03210 -0.7 -4.5 bifunctional acetylornithine aminotransferase and succinyldiaminopimelate aminotransferase compare
ECD_00938 -0.7 -1.2 aliphatic sulfonate ABC transporter permease compare
ECD_00835 -0.7 -1.6 hypothetical protein compare
ECD_02584 -0.7 -1.2 serine/threonine-specific protein phosphatase 2 compare
ECD_04126 -0.7 -4.5 multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site-specific recombination factor compare
ECD_03096 -0.7 -1.3 malate dehydrogenase, NAD(P)-binding compare
ECD_01749 -0.7 -1.5 D-hexose-6-phosphate epimerase-like protein compare
ECD_02951 -0.7 -0.8 antitoxinof the HigB-HigA toxin-antitoxin system compare
ECD_02738 -0.7 -1.0 2-octaprenylphenol hydroxylase, FAD-dependent compare
ECD_02416 -0.7 -1.8 Fe(2+) donor and activity modulator for cysteine desulfurase compare
ECD_01307 -0.7 -1.4 murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit compare
ECD_03668 -0.7 -1.8 TDP-fucosamine acetyltransferase compare
ECD_00612 -0.7 -1.3 DUF1451 family protein compare
ECD_03256 -0.7 -2.8 sensory histidine kinase in two-component regulatory system with OmpR compare
ECD_02724 -0.7 -4.4 ssDNA exonuclease, 5 compare
ECD_01404 -0.7 -1.6 DUF606 family inner membrane protein compare
ECD_00556 -0.7 -0.9 iron-enterobactin ABC transporter permease compare
ECD_02718 -0.7 -2.6 putative 4Fe-4S ferredoxin-type oxidoreductase subunit compare
ECD_00684 -0.7 -0.8 succinate dehydrogenase, FeS subunit compare
ECD_03866 -0.7 -4.7 tyrosine lyase, involved in thiamine-thiazole moiety synthesis compare
ECD_03870 -0.7 -4.5 thiamine phosphate synthase (thiamine phosphate pyrophosphorylase) compare
ECD_00795 -0.7 -2.2 Isoaspartyl peptidase compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source D-Glucose in Escherichia coli BL21

For carbon source D-Glucose across organisms