Experiment set10IT082 for Escherichia coli BW25113

Compare to:

LB Anaerobic with Azlocillin sodium salt 0.000015625 mM

200 most important genes:

  gene name fitness t score description  
b1105 ycfM -6.4 -4.4 predicted outer membrane lipoprotein (NCBI) compare
b4392 slt -5.0 -14.6 soluble lytic murein transglycosylase (VIMSS) compare
b0149 mrcB -4.7 -7.2 penicillin-binding protein 1b (NCBI) compare
b1334 fnr -4.1 -2.8 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b4237 nrdG -3.9 -10.2 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4025 pgi -3.3 -8.0 glucose-6-phosphate isomerase (NCBI) compare
b4238 nrdD -3.3 -17.3 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b0740 tolB -3.2 -2.2 translocation protein TolB precursor (NCBI) compare
b0741 pal -3.1 -2.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1192 ldcA -3.1 -5.2 L,D-carboxypeptidase A (NCBI) compare
b0053 surA -2.8 -3.4 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1361 ydaW -2.8 -1.6 orf, hypothetical protein (VIMSS) compare
b3792 wzxE -2.7 -5.2 O-antigen translocase (NCBI) compare
b0902 pflA -2.6 -7.4 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b2168 fruK -2.5 -1.7 1-phosphofructokinase (NCBI) compare
b2512 yfgL -2.5 -6.1 protein assembly complex, lipoprotein component (NCBI) compare
b4053 alr -2.5 -8.7 alanine racemase (NCBI) compare
b0737 tolQ -2.5 -1.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0739 tolA -2.4 -1.7 cell envelope integrity inner membrane protein TolA (NCBI) compare
b4520 ymgF -2.3 -1.5 hypothetical protein (NCBI) compare
b3443 yrhA -2.3 -2.2 orf, hypothetical protein (VIMSS) compare
b1575 dicB -2.2 -2.0 Qin prophage; cell division inhibition protein (NCBI) compare
b3839 tatC -2.2 -6.5 TatABCE protein translocation system subunit (NCBI) compare
b2330 yfcB -2.2 -1.5 putative adenine-specific methylase (VIMSS) compare
b1476 fdnI -2.2 -1.7 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b0239 frsA -2.2 -9.2 fermentation/respiration switch protein (NCBI) compare
b0730 mngR -2.0 -1.4 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b0990 cspG -2.0 -1.8 DNA-binding transcriptional regulator (NCBI) compare
b3620 rfaF -2.0 -5.0 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2531 iscR -1.9 -1.5 DNA-binding transcriptional repressor (NCBI) compare
b3390 aroK -1.9 -2.2 shikimate kinase I (NCBI) compare
b4592 yccB -1.9 -2.5 hypothetical protein (RefSeq) compare
b0142 folK -1.9 -1.0 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0433 ampG -1.9 -13.3 muropeptide transporter (NCBI) compare
b0738 tolR -1.9 -1.3 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0957 ompA -1.9 -2.4 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2830 nudH -1.8 -1.2 dinucleoside polyphosphate hydrolase (NCBI) compare
b2617 smpA -1.8 -2.8 small membrane protein A (VIMSS) compare
b1176 minC -1.8 -3.1 septum formation inhibitor (NCBI) compare
b1290 sapF -1.8 -1.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0903 pflB -1.8 -10.1 pyruvate formate lyase I (NCBI) compare
b4402 yjjY -1.8 -1.2 hypothetical protein (NCBI) compare
b0462 acrB -1.7 -12.4 multidrug efflux system protein (NCBI) compare
b1882 cheY -1.7 -0.9 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1530 marR -1.7 -3.5 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b3183 obgE -1.7 -1.1 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1567 intK -1.7 -2.1 Qin prophage; predicted protein (RefSeq) compare
b1600 mdtJ -1.6 -1.1 multidrug efflux system transporter (NCBI) compare
b3930 menA -1.6 -10.9 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b0357 yaiN -1.5 -2.3 putative alpha helix chain (VIMSS) compare
b3035 tolC -1.5 -7.1 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b4181 yjfI -1.5 -2.0 hypothetical protein (NCBI) compare
b0407 yajC -1.5 -2.7 preprotein translocase subunit YajC (NCBI) compare
b0827 moeA -1.5 -4.7 molybdopterin biosynthesis protein (NCBI) compare
b1861 ruvA -1.5 -0.9 Holliday junction DNA helicase motor protein (NCBI) compare
b0381 ddlA -1.4 -5.8 D-alanylalanine synthetase (NCBI) compare
b1850 eda -1.4 -2.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3052 rfaE -1.4 -4.1 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0014 dnaK -1.4 -1.8 molecular chaperone DnaK (NCBI) compare
b0463 acrA -1.4 -7.7 multidrug efflux system (NCBI) compare
b4603 rseX -1.4 -1.0 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b2363 yfdT -1.3 -2.1 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1865 nudB -1.3 -1.5 dATP pyrophosphohydrolase (NCBI) compare
b3621 rfaC -1.3 -4.1 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1108 ycfP -1.3 -3.1 orf, hypothetical protein (VIMSS) compare
b3838 tatB -1.3 -5.0 sec-independent translocase (NCBI) compare
b2114 metG -1.3 -2.0 methionyl-tRNA synthetase (NCBI) compare
b1332 ynaJ -1.3 -0.8 predicted inner membrane protein (NCBI) compare
b4503 yafF -1.3 -0.8 no description compare
b0765 modC -1.3 -4.5 molybdate transporter subunit (NCBI) compare
b1013 ycdC -1.3 -2.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b1161 ycgX -1.2 -0.8 hypothetical protein (NCBI) compare
b2567 rnc -1.2 -0.8 ribonuclease III (NCBI) compare
b4701 sokX -1.2 -1.1 sok-related sRNA, function unknown (RefSeq) compare
b2479 gcvR -1.2 -3.8 transcriptional regulation of gcv operon (VIMSS) compare
b0949 uup -1.2 -5.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b1074 flgC -1.2 -2.2 flagellar basal-body rod protein C (NCBI) compare
b4676 yoaK -1.2 -0.7 expressed protein (RefSeq) compare
b1758 b1758 -1.2 -1.4 putative cytochrome oxidase (VIMSS) compare
b1503 ydeR -1.2 -2.1 predicted fimbrial-like adhesin protein (NCBI) compare
b0364 yaiS -1.2 -2.1 orf, hypothetical protein (VIMSS) compare
b4630 ykgP -1.2 -2.0 no description compare
b1506 yneL -1.2 -0.7 predicted transcriptional regulator (NCBI) compare
b0145 dksA -1.1 -2.6 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2576 srmB -1.1 -2.1 ATP-dependent RNA helicase (NCBI) compare
b2935 tktA -1.1 -0.8 transketolase 1, thiamin-binding (NCBI) compare
b4375 prfC -1.1 -1.7 peptide chain release factor 3 (NCBI) compare
b1273 yciN -1.1 -1.6 hypothetical protein (NCBI) compare
b0439 lon -1.1 -3.3 DNA-binding ATP-dependent protease La (NCBI) compare
b1259 yciG -1.1 -1.4 orf, hypothetical protein (VIMSS) compare
b3500 gor -1.1 -1.2 glutathione reductase (NCBI) compare
b1370 insH-5 -1.1 -2.1 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b3761 trpT -1.1 -1.5 tRNA-Trp (NCBI) compare
b0564 appY -1.1 -1.0 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1874 cutC -1.1 -1.8 copper homeostasis protein (NCBI) compare
b3619 rfaD -1.1 -2.8 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1175 minD -1.1 -2.7 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0450 glnK -1.1 -1.6 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b1730 ydjO -1.1 -0.7 predicted protein (RefSeq) compare
b0386 proC -1.0 -2.9 pyrroline-5-carboxylate reductase (NCBI) compare
b3857 mobA -1.0 -3.4 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b0783 moaC -1.0 -3.6 molybdenum cofactor biosynthesis protein C (NCBI) compare
b1205 ychH -1.0 -2.1 predicted inner membrane protein (NCBI) compare
b1677 lpp -1.0 -1.7 murein lipoprotein (NCBI) compare
b3164 pnp -1.0 -1.8 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0434 yajG -1.0 -3.9 putative polymerase/proteinase (VIMSS) compare
b2189 proL -1.0 -1.6 tRNA-Pro (NCBI) compare
b3836 b3836 -1.0 -3.2 orf, hypothetical protein (VIMSS) compare
b2642 yfjW -1.0 -0.9 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b0826 moeB -1.0 -4.1 molybdopterin biosynthesis protein MoeB (NCBI) compare
b3229 sspA -1.0 -1.8 stringent starvation protein A (NCBI) compare
b2911 ssrS -1.0 -1.5 6S regulatory RNA (NCBI) compare
b3790 rffC -1.0 -3.7 TDP-fucosamine acetyltransferase (RefSeq) compare
b1686 ydiI -1.0 -1.6 hypothetical protein (NCBI) compare
b3199 yrbK -1.0 -1.9 hypothetical protein (NCBI) compare
b1951 rcsA -0.9 -0.6 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b1954 dsrA -0.9 -1.6 regulatory antisense RNA (NCBI) compare
b3493 pitA -0.9 -3.8 phosphate transporter, low-affinity (NCBI) compare
b3613 yibP -0.9 -1.1 putative membrane protein (VIMSS) compare
b2506 yfgI -0.9 -1.4 hypothetical protein (NCBI) compare
b1969 yedW -0.9 -2.4 putative 2-component transcriptional regulator (VIMSS) compare
b2820 recB -0.9 -0.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2620 smpB -0.9 -1.0 SsrA-binding protein (NCBI) compare
b4640 yoeG -0.9 -1.2 no description compare
b1465 narV -0.9 -1.9 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b3617 kbl -0.9 -4.1 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b0728 sucC -0.9 -3.3 succinyl-CoA synthetase subunit beta (NCBI) compare
b4146 yjeK -0.9 -0.8 predicted lysine aminomutase (NCBI) compare
b3405 ompR -0.9 -2.9 osmolarity response regulator (NCBI) compare
b0677 nagA -0.9 -3.5 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b2215 ompC -0.9 -4.9 outer membrane porin protein C (NCBI) compare
b0049 apaH -0.9 -1.7 diadenosinetetraphosphatase (NCBI) compare
b4509 ylcG -0.9 -1.9 DLP12 prophage; predicted protein (NCBI) compare
b4201 priB -0.9 -1.7 primosomal replication protein N (NCBI) compare
b2572 rseA -0.9 -3.0 anti-sigma factor (NCBI) compare
b1536 ydeI -0.9 -0.6 hypothetical protein (NCBI) compare
b0781 moaA -0.9 -4.8 molybdenum cofactor biosynthesis protein A (NCBI) compare
b0764 modB -0.9 -2.7 molybdate ABC transporter permease protein (NCBI) compare
b0688 pgm -0.8 -2.1 phosphoglucomutase (NCBI) compare
b4679 yohP -0.8 -1.8 expressed protein (RefSeq) compare
b1785 yeaI -0.8 -1.1 predicted diguanylate cyclase (NCBI) compare
b1286 rnb -0.8 -1.6 exoribonuclease II (NCBI) compare
b2343 b2343 -0.8 -1.3 orf, hypothetical protein (VIMSS) compare
b1236 galU -0.8 -2.4 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0729 sucD -0.8 -1.7 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1926 fliT -0.8 -1.0 predicted chaperone (NCBI) compare
b0908 aroA -0.8 -4.6 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b2450 yffS -0.8 -1.5 CPZ-55 prophage; predicted protein (RefSeq) compare
b1308 pspE -0.8 -2.9 thiosulfate:cyanide sulfurtransferase (rhodanese) (NCBI) compare
b1160 elbA -0.8 -0.5 hypothetical protein (NCBI) compare
b2271 yfbL -0.8 -3.1 putative aminopeptidase (VIMSS) compare
b4702 mgtL -0.8 -1.3 regulatory leader peptide for mgtA (NCBI) compare
b2083 yegZ -0.8 -1.6 orf, hypothetical protein (VIMSS) compare
b2937 speB -0.8 -3.6 agmatinase (NCBI) compare
b0761 modE -0.8 -4.0 DNA-binding transcriptional dual regulator (NCBI) compare
b3404 envZ -0.8 -4.7 osmolarity sensor protein (NCBI) compare
b0009 mog -0.8 -4.1 molybdenum cofactor biosynthesis protein (NCBI) compare
b1824 yobF -0.8 -1.5 hypothetical protein (NCBI) compare
b1357 ydaS -0.8 -1.5 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b1063 yceB -0.8 -1.9 predicted lipoprotein (NCBI) compare
b1040 csgD -0.8 -0.5 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b3537 yhjT -0.8 -2.8 orf, hypothetical protein (VIMSS) compare
b4202 rpsR -0.8 -0.7 30S ribosomal protein S18 (NCBI) compare
b2951 yggS -0.8 -2.9 predicted enzyme (NCBI) compare
b1579 intQ -0.8 -1.3 Qin prophage; predicted defective integrase (RefSeq) compare
b2259 pmrD -0.8 -0.7 polymyxin resistance protein B (VIMSS) compare
b1961 dcm -0.8 -1.4 DNA cytosine methylase (NCBI) compare
b1765 ydjA -0.8 -0.8 predicted oxidoreductase (NCBI) compare
b1847 yebF -0.7 -1.2 predicted protein (RefSeq) compare
b3933 ftsN -0.7 -3.8 essential cell division protein (NCBI) compare
b4239 treC -0.7 -1.2 trehalose-6-P hydrolase (NCBI) compare
b3631 rfaG -0.7 -5.4 glucosyltransferase I (NCBI) compare
b0630 lipB -0.7 -0.9 protein of lipoate biosynthesis (VIMSS) compare
b0763 modA -0.7 -2.9 molybdate transporter subunit (NCBI) compare
b3999 yjaG -0.7 -2.7 hypothetical protein (NCBI) compare
b4171 miaA -0.7 -1.7 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b0508 hyi -0.7 -1.2 hydroxypyruvate isomerase (NCBI) compare
b3626 rfaJ -0.7 -1.5 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b4579 yaiX -0.7 -2.4 no description compare
b1278 pgpB -0.7 -1.7 phosphatidylglycerophosphatase B (NCBI) compare
b1612 fumA -0.7 -2.0 fumarate hydratase (fumarase A), aerobic Class I (NCBI) compare
b1121 ycfZ -0.7 -0.5 predicted inner membrane protein (NCBI) compare
b3784 rfe -0.7 -5.2 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b2085 b2085 -0.7 -1.7 orf, hypothetical protein (VIMSS) compare
b3469 zntA -0.7 -3.4 zinc, cobalt and lead efflux system (NCBI) compare
b3162 deaD -0.7 -2.0 inducible ATP-independent RNA helicase (VIMSS) compare
b1818 manY -0.7 -1.4 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1196 ycgY -0.7 -1.4 hypothetical protein (NCBI) compare
b2237 inaA -0.7 -1.9 hypothetical protein (NCBI) compare
b0436 tig -0.7 -4.0 trigger factor (NCBI) compare
b2993 hybD -0.7 -2.1 predicted maturation element for hydrogenase 2 (NCBI) compare
b1505 ydeT -0.7 -0.5 hypothetical protein (RefSeq) compare
b1462 b1462 -0.7 -1.7 orf, hypothetical protein (VIMSS) compare
b1875 yecM -0.7 -2.5 orf, hypothetical protein (VIMSS) compare
b4505 insX -0.7 -0.9 predicted IS protein (RefSeq) compare
b1773 ydjI -0.7 -0.6 predicted aldolase (NCBI) compare
b3629 rfaS -0.7 -1.3 lipopolysaccharide core biosynthesis protein (NCBI) compare
b0222 lpcA -0.7 -1.3 phosphoheptose isomerase (NCBI) compare
b0499 ylbH -0.7 -1.7 conserved protein, rhs-like (RefSeq) compare
b1542 ydfI -0.7 -2.2 predicted mannonate dehydrogenase (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For stress Azlocillin sodium salt in Escherichia coli BW25113

For stress Azlocillin sodium salt across organisms