Experiment set10IT076 for Escherichia coli BW25113

Compare to:

LB Anaerobic with Phenazine ethosulfate 0.000125 mM

200 most important genes:

  gene name fitness t score description  
b4237 nrdG -5.7 -9.6 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4238 nrdD -5.4 -16.1 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b0462 acrB -5.2 -14.5 multidrug efflux system protein (NCBI) compare
b0463 acrA -5.0 -10.2 multidrug efflux system (NCBI) compare
b3035 tolC -4.5 -4.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b1085 b1085 -4.0 -2.8 orf, hypothetical protein (VIMSS) compare
b1334 fnr -3.8 -2.6 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b0623 cspE -3.8 -2.2 cold shock protein E (NCBI) compare
b0902 pflA -3.7 -8.6 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b1476 fdnI -3.6 -1.4 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b1765 ydjA -3.5 -1.4 predicted oxidoreductase (NCBI) compare
b0903 pflB -3.2 -13.5 pyruvate formate lyase I (NCBI) compare
b0990 cspG -2.9 -2.0 DNA-binding transcriptional regulator (NCBI) compare
b0145 dksA -2.9 -2.8 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b4603 rseX -2.8 -1.1 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1818 manY -2.7 -3.0 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1493 gadB -2.7 -1.1 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1273 yciN -2.7 -1.2 hypothetical protein (NCBI) compare
b0053 surA -2.6 -3.9 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1361 ydaW -2.6 -1.0 orf, hypothetical protein (VIMSS) compare
b2620 smpB -2.4 -1.6 SsrA-binding protein (NCBI) compare
b1518 lsrG -2.4 -1.8 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b0239 frsA -2.4 -6.3 fermentation/respiration switch protein (NCBI) compare
b2808 gcvA -2.4 -3.2 DNA-binding transcriptional dual regulator (NCBI) compare
b4025 pgi -2.4 -8.7 glucose-6-phosphate isomerase (NCBI) compare
b0222 lpcA -2.3 -3.1 phosphoheptose isomerase (NCBI) compare
b2329 aroC -2.2 -5.6 chorismate synthase (NCBI) compare
b0014 dnaK -2.2 -2.1 molecular chaperone DnaK (NCBI) compare
b3617 kbl -2.1 -7.2 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b1104 ycfL -2.1 -2.1 hypothetical protein (NCBI) compare
b0927 ycbL -2.1 -3.3 predicted metal-binding enzyme (NCBI) compare
b1863 ruvC -2.1 -1.4 Holliday junction resolvase (NCBI) compare
b4520 ymgF -2.0 -1.4 hypothetical protein (NCBI) compare
b0605 ahpC -2.0 -4.1 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b3619 rfaD -2.0 -3.3 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0560 nohB -2.0 -2.0 DLP12 prophage; DNA packaging protein (NCBI) compare
b2181 yejG -2.0 -4.4 hypothetical protein (NCBI) compare
b3164 pnp -1.9 -2.9 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0688 pgm -1.9 -3.1 phosphoglucomutase (NCBI) compare
b1380 ldhA -1.9 -2.4 D-lactate dehydrogenase (NCBI) compare
b3229 sspA -1.9 -2.3 stringent starvation protein A (NCBI) compare
b2479 gcvR -1.9 -4.7 transcriptional regulation of gcv operon (VIMSS) compare
b0113 pdhR -1.9 -4.4 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b0142 folK -1.9 -0.7 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b4410 ecnA -1.9 -1.5 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b3387 dam -1.9 -9.5 DNA adenine methylase (NCBI) compare
b4529 ydbJ -1.9 -1.0 hypothetical protein (NCBI) compare
b4702 mgtL -1.8 -1.7 regulatory leader peptide for mgtA (NCBI) compare
b0237 pepD -1.8 -7.0 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b1164 ycgZ -1.8 -1.7 hypothetical protein (NCBI) compare
b2501 ppk -1.8 -7.8 polyphosphate kinase (NCBI) compare
b1259 yciG -1.8 -1.0 orf, hypothetical protein (VIMSS) compare
b4201 priB -1.8 -2.9 primosomal replication protein N (NCBI) compare
b0908 aroA -1.8 -8.1 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b3082 ygjM -1.8 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1360 ydaV -1.8 -3.1 Rac prophage; predicted DNA replication protein (NCBI) compare
b1533 ydeD -1.8 -2.2 orf, hypothetical protein (VIMSS) compare
b4402 yjjY -1.8 -0.9 hypothetical protein (NCBI) compare
b1567 intK -1.8 -2.6 Qin prophage; predicted protein (RefSeq) compare
b1709 btuD -1.7 -0.9 vitamin B12-transporter ATPase (NCBI) compare
b2576 srmB -1.7 -2.6 ATP-dependent RNA helicase (NCBI) compare
b2450 yffS -1.7 -1.8 CPZ-55 prophage; predicted protein (RefSeq) compare
b3792 wzxE -1.7 -6.1 O-antigen translocase (NCBI) compare
b3842 rfaH -1.7 -5.4 transcriptional activator RfaH (NCBI) compare
b3443 yrhA -1.7 -1.9 orf, hypothetical protein (VIMSS) compare
b3616 tdh -1.7 -5.3 L-threonine 3-dehydrogenase (NCBI) compare
b3609 secB -1.7 -3.3 export protein SecB (NCBI) compare
b4426 isrA -1.7 -2.2 unknown RNA (NCBI) compare
b2783 chpR -1.7 -1.6 antitoxin of the ChpA-ChpR toxin-antitoxin system (NCBI) compare
b3237 argR -1.7 -3.9 arginine repressor (NCBI) compare
b1865 nudB -1.7 -1.5 dATP pyrophosphohydrolase (NCBI) compare
b4062 soxS -1.7 -3.1 DNA-binding transcriptional dual regulator (NCBI) compare
b3026 qseC -1.7 -1.1 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1293 sapB -1.6 -1.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1291 sapD -1.6 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3545 proK -1.6 -1.8 tRNA-Pro (NCBI) compare
b3621 rfaC -1.6 -4.7 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2168 fruK -1.6 -1.4 1-phosphofructokinase (NCBI) compare
b1292 sapC -1.6 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1847 yebF -1.5 -1.6 predicted protein (RefSeq) compare
b3052 rfaE -1.5 -4.2 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1676 pykF -1.5 -3.2 pyruvate kinase (NCBI) compare
b3631 rfaG -1.5 -9.5 glucosyltransferase I (NCBI) compare
b4557 yidD -1.5 -3.3 hypothetical protein (NCBI) compare
b4505 insX -1.5 -1.6 predicted IS protein (RefSeq) compare
b3931 hslU -1.5 -7.5 ATP-dependent protease ATP-binding subunit (NCBI) compare
b3465 yhhF -1.4 -4.5 predicted methyltransferase (NCBI) compare
b0357 yaiN -1.4 -1.9 putative alpha helix chain (VIMSS) compare
b3032 cpdA -1.4 -4.0 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b1147 ymfL -1.4 -2.2 e14 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b4203 rplI -1.4 -3.4 50S ribosomal protein L9 (NCBI) compare
b1531 marA -1.4 -1.6 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b0957 ompA -1.4 -2.3 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b1954 dsrA -1.4 -1.6 regulatory antisense RNA (NCBI) compare
b4655 ythA -1.4 -1.2 expressed protein (RefSeq) compare
b0406 tgt -1.4 -5.1 queuine tRNA-ribosyltransferase (NCBI) compare
b2369 evgA -1.3 -0.9 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b3620 rfaF -1.3 -4.6 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2506 yfgI -1.3 -1.7 hypothetical protein (NCBI) compare
b2189 proL -1.3 -1.4 tRNA-Pro (NCBI) compare
b2330 yfcB -1.3 -1.2 putative adenine-specific methylase (VIMSS) compare
b4178 yjeB -1.3 -3.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b3469 zntA -1.3 -5.6 zinc, cobalt and lead efflux system (NCBI) compare
b0730 mngR -1.3 -1.2 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b0238 gpt -1.3 -2.7 xanthine phosphoribosyltransferase (NCBI) compare
b1573 ydfC -1.3 -1.1 Qin prophage; predicted protein (RefSeq) compare
b4570 lomR -1.3 -1.6 no description compare
b2363 yfdT -1.3 -2.2 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1358 ydaT -1.3 -1.0 Rac prophage; predicted protein (NCBI) compare
b1950 fliR -1.3 -1.7 flagellar biosynthesis protein R (NCBI) compare
b4152 frdC -1.3 -2.4 fumarate reductase subunit C (NCBI) compare
b2553 glnB -1.3 -2.8 regulatory protein P-II for glutamine synthetase (NCBI) compare
b1936 intG -1.3 -0.8 predicted defective phage integrase (pseudogene) (RefSeq) compare
b1642 slyA -1.3 -1.1 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b1175 minD -1.3 -3.8 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0386 proC -1.2 -3.3 pyrroline-5-carboxylate reductase (NCBI) compare
b3790 rffC -1.2 -3.6 TDP-fucosamine acetyltransferase (RefSeq) compare
b2248 yfaX -1.2 -1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1861 ruvA -1.2 -0.8 Holliday junction DNA helicase motor protein (NCBI) compare
b4701 sokX -1.2 -0.9 sok-related sRNA, function unknown (RefSeq) compare
b0949 uup -1.2 -4.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b1804 rnd -1.2 -3.2 ribonuclease D (NCBI) compare
b1557 cspB -1.2 -1.6 Qin prophage; cold shock protein (NCBI) compare
b2689 yqaA -1.2 -2.1 conserved inner membrane protein (NCBI) compare
b2376 ypdI -1.2 -2.1 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b4535 yniD -1.2 -1.1 predicted protein (RefSeq) compare
b3226 yhcK -1.2 -4.0 putative FADA-type transcriptional regulator (VIMSS) compare
b2266 elaB -1.2 -2.2 hypothetical protein (NCBI) compare
b4503 yafF -1.2 -0.6 no description compare
b0364 yaiS -1.2 -1.9 orf, hypothetical protein (VIMSS) compare
b0122 yacC -1.2 -2.8 orf, hypothetical protein (VIMSS) compare
b3630 rfaP -1.2 -5.9 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b4243 yjgF -1.2 -3.9 orf, hypothetical protein (VIMSS) compare
b2136 yohD -1.2 -1.3 orf, hypothetical protein (VIMSS) compare
b1530 marR -1.2 -4.9 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b3500 gor -1.2 -1.3 glutathione reductase (NCBI) compare
b1572 ydfB -1.2 -1.2 orf, hypothetical protein (VIMSS) compare
b1344 ydaO -1.2 -2.7 predicted C32 tRNA thiolase (NCBI) compare
b0660 ybeZ -1.2 -3.0 predicted protein with nucleoside triphosphate hydrolase domain (RefSeq) compare
b4686 yshB -1.2 -2.9 expressed protein (RefSeq) compare
b1236 galU -1.2 -2.7 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1686 ydiI -1.2 -0.8 hypothetical protein (NCBI) compare
b4053 alr -1.1 -6.0 alanine racemase (NCBI) compare
b3129 sohA -1.1 -2.2 predicted regulator (NCBI) compare
b0499 ylbH -1.1 -2.2 conserved protein, rhs-like (RefSeq) compare
b3649 rpoZ -1.1 -1.9 DNA-directed RNA polymerase subunit omega (NCBI) compare
b1600 mdtJ -1.1 -1.0 multidrug efflux system transporter (NCBI) compare
b3628 rfaB -1.1 -5.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b1707 ydiV -1.1 -2.4 hypothetical protein (NCBI) compare
b2567 rnc -1.1 -0.7 ribonuclease III (NCBI) compare
b1862 yebB -1.1 -2.2 orf, hypothetical protein (VIMSS) compare
b0263 afuB -1.1 -1.7 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b1103 ycfF -1.1 -1.0 orf, hypothetical protein (VIMSS) compare
b1920 fliY -1.1 -1.2 cystine transporter subunit (NCBI) compare
b3916 pfkA -1.1 -1.3 6-phosphofructokinase (NCBI) compare
b2623 yfjH -1.1 -3.5 CP4-57 prophage; predicted protein (NCBI) compare
b4181 yjfI -1.1 -2.3 hypothetical protein (NCBI) compare
b4068 yjcH -1.1 -2.4 required for glycolate transport, with actP (from data) compare
b0989 cspH -1.1 -1.0 stress protein, member of the CspA-family (NCBI) compare
b3932 hslV -1.1 -5.0 ATP-dependent protease peptidase subunit (NCBI) compare
b3563 yiaB -1.1 -2.4 orf, hypothetical protein (VIMSS) compare
b0739 tolA -1.1 -2.0 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2894 xerD -1.1 -0.7 site-specific tyrosine recombinase XerD (NCBI) compare
b3627 rfaI -1.1 -5.4 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b2157 yeiE -1.1 -2.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b1558 cspF -1.1 -1.5 Qin prophage; cold shock protein (NCBI) compare
b4151 frdD -1.1 -2.2 fumarate reductase subunit D (NCBI) compare
b0232 yafN -1.1 -0.6 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1332 ynaJ -1.0 -0.5 predicted inner membrane protein (NCBI) compare
b2085 b2085 -1.0 -2.4 orf, hypothetical protein (VIMSS) compare
b4676 yoaK -1.0 -0.5 expressed protein (RefSeq) compare
b2209 eco -1.0 -1.3 ecotin precursor (NCBI) compare
b1333 uspE -1.0 -2.7 stress-induced protein (NCBI) compare
b0746 valZ -1.0 -1.5 tRNA-Val (NCBI) compare
b3794 rffM -1.0 -4.7 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b2637 yfjT -1.0 -1.6 CP4-57 prophage; predicted protein (NCBI) compare
b2424 cysU -1.0 -2.0 sulfate/thiosulfate transporter subunit (NCBI) compare
b4191 ulaR -1.0 -2.0 DNA-binding transcriptional dual regulator (NCBI) compare
b2727 hypB -1.0 -2.3 GTP hydrolase involved in nickel liganding into hydrogenases (NCBI) compare
b1217 chaB -1.0 -0.7 cation transport regulator (NCBI) compare
b2071 yegJ -1.0 -1.1 hypothetical protein (NCBI) compare
b4375 prfC -1.0 -1.7 peptide chain release factor 3 (NCBI) compare
b2477 nlpB -1.0 -2.0 lipoprotein-34 (VIMSS) compare
b2820 recB -1.0 -0.7 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b4146 yjeK -1.0 -0.7 predicted lysine aminomutase (NCBI) compare
b2498 upp -1.0 -1.7 uracil phosphoribosyltransferase (VIMSS) compare
b2314 dedD -1.0 -1.8 putative lipoprotein (VIMSS) compare
b3784 rfe -1.0 -5.8 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b0407 yajC -1.0 -1.4 preprotein translocase subunit YajC (NCBI) compare
b0436 tig -1.0 -3.8 trigger factor (NCBI) compare
b2910 zapA -1.0 -3.0 protein that localizes to the cytokinetic ring (NCBI) compare
b2271 yfbL -1.0 -3.6 putative aminopeptidase (VIMSS) compare
b1566 flxA -1.0 -2.3 Qin prophage; predicted protein (NCBI) compare
b0759 galE -1.0 -3.9 UDP-galactose-4-epimerase (VIMSS) compare
b2362 yfdS -0.9 -3.1 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1223 narK -0.9 -3.0 nitrate/nitrite transporter (NCBI) compare
b2569 lepA -0.9 -2.4 GTP-binding protein LepA (NCBI) compare
b1329 b1329 -0.9 -3.0 putative transport periplasmic protein (VIMSS) compare
b1330 ynaI -0.9 -2.3 conserved inner membrane protein (NCBI) compare
b2977 glcG -0.9 -2.7 hypothetical protein (NCBI) compare


Specific Phenotypes

For 15 genes in this experiment

For stress Phenazine ethosulfate in Escherichia coli BW25113

For stress Phenazine ethosulfate across organisms