Experiment set10IT062 for Pseudomonas putida KT2440

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Myristic acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_5053 +3.0 10.6 Protein-export protein SecB compare
PP_1623 +2.7 19.7 RNA polymerase, sigma S (sigma 38) factor compare
PP_4171 +2.5 11.8 conserved exported protein of unknown function compare
PP_1650 +2.3 19.2 Sensor protein GacS compare
PP_5225 +2.1 3.4 frataxin compare
PP_4099 +2.0 19.4 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1562 +1.9 3.6 putative Phage terminase, small subunit compare
PP_1208 +1.8 1.9 conserved protein of unknown function, SlyX family compare
PP_1217 +1.8 3.8 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_2999 +1.7 1.6 Glyoxalase family protein compare
PP_5313 +1.7 3.5 DNA-binding protein HU-alpha compare
PP_2889 +1.7 4.2 putative Transmembrane regulator PrtR compare
PP_1216 +1.6 3.3 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_1778 +1.6 5.1 Lipopolysaccharide ABC export system, permease protein compare
PP_3378 +1.6 2.8 putative 2-ketogluconokinase compare
PP_0653 +1.6 2.2 conserved protein of unknown function compare
PP_4994 +1.6 5.7 conserved protein of unknown function compare
PP_1779 +1.6 6.0 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_4004 +1.5 2.7 DNA translocase FtsK compare
PP_1569 +1.5 4.3 conserved protein of unknown function compare
PP_0048 +1.5 1.9 conserved protein of unknown function compare
PP_1571 +1.4 2.5 conserved protein of unknown function compare
PP_1560 +1.4 4.9 conserved protein of unknown function compare
PP_4697 +1.4 3.0 poly(A) polymerase compare
PP_1561 +1.4 5.0 putative Phage holin compare
PP_1113 +1.4 6.8 Pyridoxal-phosphate dependent enzyme family protein compare
PP_1548 +1.4 1.4 conserved protein of unknown function compare
PP_1565 +1.3 6.0 Phage portal protein, HK97 family compare
PP_2309 +1.3 1.3 conserved protein of unknown function compare
PP_2414 +1.3 2.9 conserved exported protein of unknown function compare
PP_4942 +1.3 1.7 conserved protein of unknown function compare
PP_3726 +1.3 1.4 Enoyl-CoA hydratase/isomerase family protein compare
PP_5706 +1.3 1.8 Sec translocation complex - SecG subunit compare
PP_1567 +1.3 6.3 Capsid protein compare
PP_1566 +1.3 3.2 Peptidase U35 compare
PP_1862 +1.3 3.1 conserved membrane protein of unknown function compare
PP_5145 +1.2 11.4 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_1564 +1.2 4.8 conserved exported protein of unknown function compare
PP_1546 +1.2 4.0 conserved protein of unknown function compare
PP_1207 +1.2 2.5 conserved protein of unknown function compare
PP_1198 +1.2 2.0 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_1563 +1.2 7.4 putative Phage terminase, large subunit compare
PP_3245 +1.2 1.2 conserved protein of unknown function compare
PP_2341 +1.2 1.2 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_3831 +1.2 3.5 conserved protein of unknown function compare
PP_1690 +1.2 4.0 conserved protein of unknown function compare
PP_1584 +1.2 3.8 conserved protein of unknown function compare
PP_5140 +1.1 2.5 Transcriptional regulator, MerR family compare
PP_1938 +1.1 2.0 conserved protein of unknown function compare
PP_0025 +1.1 1.4 hypothetical protein compare
PP_1573 +1.1 3.9 putative Major tail protein compare
PP_0630 +1.1 1.1 DNA gyrase inhibitor YacG compare
PP_2900 +1.1 2.5 conserved protein of unknown function compare
PP_0834 +1.1 1.4 Sec translocation complex subunit YajC compare
PP_0022 +1.1 1.0 hypothetical protein compare
PP_5546 +1.1 1.3 conserved protein of unknown function compare
PP_2583 +1.1 2.5 Acetyltransferase, GNAT family compare
PP_3876 +1.1 2.1 conserved protein of unknown function compare
PP_2055 +1.1 2.6 putative isomerase compare
PP_1572 +1.0 5.5 conserved protein of unknown function compare
PP_0962 +1.0 1.9 toluene-tolerance protein compare
PP_1577 +1.0 7.1 Phage tail tape meausure protein, lambda family compare
PP_3392 +1.0 1.0 conserved protein of unknown function compare
PP_1215 +1.0 0.8 Crossover junction endodeoxyribonuclease RuvC compare
PP_4966 +1.0 2.7 transcriptional regulator of methionine metabolism compare
PP_5393 +1.0 1.3 putative metal-binding chaperone compare
PP_5476 +1.0 4.5 conserved protein of unknown function compare
PP_3808 +1.0 0.6 Antibiotic synthesis protein MbtH compare
PP_1576 +1.0 2.7 putative Immunity protein compare
PP_4100 +1.0 3.1 Transcriptional regulator, Cro/CI family compare
PP_1579 +1.0 6.9 conserved protein of unknown function compare
PP_1442 +1.0 2.3 conserved protein of unknown function compare
PP_1580 +1.0 5.5 conserved protein of unknown function compare
PP_4424 +1.0 0.8 Uncharacterized HTH-type transcriptional regulator y4tD compare
PP_4769 +1.0 1.6 conserved protein of unknown function compare
PP_4792 +0.9 1.5 conserved exported protein of unknown function compare
PP_5094 +0.9 1.9 putative enzyme with PLP binding domain compare
PP_5514 +0.9 2.6 conserved protein of unknown function compare
PP_0821 +0.9 2.9 conserved exported protein of unknown function compare
PP_1112 +0.9 4.4 conserved membrane protein of unknown function compare
PP_5000 +0.9 1.0 peptidase component of the ATP-dependent HslVU protease compare
PP_2568 +0.9 0.7 Ring-cleaving dioxygenase compare
PP_1041 +0.9 1.6 twin arginine protein export complex subunit compare
PP_1381 +0.9 1.1 4-carboxymuconolactone decarboxylase compare
PP_5652 +0.9 1.1 conserved protein of unknown function, phage origin compare
PP_0194 +0.9 1.7 Transcriptional regulatory protein AlgP compare
PP_3002 +0.9 1.1 shikimate dehydrogenase-related enzyme compare
PP_3190 +0.9 1.9 Ornithine cyclodeaminase/mu-crystallin family protein compare
PP_4268 +0.9 0.7 nucleoid-associated broad specificity regulator compare
PP_0825 +0.9 2.7 phosphonates import ATP-binding protein compare
PP_3825 +0.9 2.3 conserved protein of unknown function compare
PP_1326 +0.9 1.2 16S rRNA 2'-O-ribose C1402 methyltransferase compare
PP_0856 +0.9 1.7 conserved lipoprotein of unknown function compare
PP_5045 +0.9 3.0 tRNA sulfurtransferase compare
PP_2616 +0.9 2.2 conserved protein of unknown function compare
PP_4018 +0.9 1.5 Acetyltransferase, GNAT family compare
PP_0963 +0.9 1.7 putative BolA family protein compare
PP_5324 +0.9 1.7 Response regulator compare
PP_1581 +0.9 5.8 BNR domain protein compare
PP_1307 +0.9 1.8 AsnC family transcriptional regulator compare
PP_2340 +0.9 1.4 conserved protein of unknown function compare
PP_2715 +0.9 1.6 ArsH protein compare
PP_1730 +0.9 1.9 Probable M18 family aminopeptidase 2 compare
PP_1265 +0.8 1.8 conserved protein of unknown function compare
PP_2142 +0.8 1.6 Cell division inhibitor SulA compare
PP_4683 +0.8 5.2 transglycosylase/transpeptidase compare
PP_2131 +0.8 2.3 DNA-binding ATPase involved in replication compare
PP_1544 +0.8 1.8 conserved protein of unknown function compare
PP_3802 +0.8 1.8 putative Cation ABC transporter, ATP-binding protein compare
PP_3017 +0.8 1.5 O6-methylguanine-DNA methyltransferase compare
PP_4817 +0.8 1.7 MaoC domain protein compare
PP_3318 +0.8 0.8 conserved protein of unknown function compare
PP_4785 +0.8 2.7 conserved exported protein of unknown function compare
PP_2654 +0.8 2.2 putative Glutathione S-transferase compare
PP_1224 +0.8 2.6 periplasmic subunit of the TolQRA transport system compare
PP_2922 +0.8 1.3 Urea amidolyase-related protein compare
PP_2280 +0.8 1.4 conserved protein of unknown function compare
PP_4517 +0.8 0.7 conserved protein of unknown function compare
PP_0508 +0.8 1.7 conserved exported protein of unknown function compare
PP_2247 +0.8 1.6 putative Endoribonuclease compare
PP_0116 +0.8 3.6 putative lipoprotein compare
PP_4555 +0.8 1.4 conserved protein of unknown function compare
PP_2308 +0.8 2.4 putative Acyl-CoA thioesterase II compare
PP_1468 +0.8 1.0 Tyrosine recombinase XerD compare
PP_1999 +0.8 1.1 membrane protein required for colicin V production compare
PP_4804 +0.8 2.4 RlpA-like lipoprotein compare
PP_1906 +0.8 2.1 ribosomal large subunit pseudouridine synthase C compare
PP_4726 +0.8 1.3 Chaperone protein DnaJ compare
PP_5499 +0.8 1.8 conserved protein of unknown function compare
PP_4701 +0.8 0.7 glucose-6-phosphate isomerase compare
PP_1774 +0.8 1.1 conserved exported protein of unknown function compare
PP_4173 +0.8 3.9 Sensor histidine kinase/response regulator compare
PP_2322 +0.8 3.3 Major outer membrane lipoprotein compare
PP_0841 +0.8 1.8 DNA-binding transcriptional dual regulator 2Fe-2S cluster IscR compare
PP_5490 +0.8 2.3 site-specific DNA recombinase compare
PP_0948 +0.8 1.5 Phosphocarrier protein HPr compare
PP_3427 +0.8 2.1 Multidrug efflux RND outer membrane protein OprN compare
PP_3312 +0.8 1.3 putative Heat shock protein compare
PP_0803 +0.8 3.6 Protein secretion ABC efflux system, membrane fusion protein compare
PP_3376 +0.8 2.3 putative phosphonate dehydrogenase compare
PP_2159 +0.8 1.9 Copper-binding protein, plastocyanin/azurin family compare
PP_5241 +0.8 1.8 DNA-binding response regulator, LuxR family compare
PP_5525 +0.8 1.6 conserved exported protein of unknown function compare
PP_0123 +0.7 2.8 DNA polymerase I, 5 compare
PP_4214 +0.7 1.8 pyoverdine biosynthesis related protein compare
PP_2858 +0.7 1.6 conserved exported protein of unknown function compare
PP_5001 +0.7 1.4 protease HslVU, ATPase component compare
PP_5548 +0.7 1.8 protein of unknown function compare
PP_2046 +0.7 1.5 Transcriptional regulator, LysR family compare
PP_2144 +0.7 1.6 Transcriptional regulator, TetR family compare
PP_4265 +0.7 1.4 DNA-binding transcriptional dual regulator compare
PP_5139 +0.7 2.4 cadmium translocating P-type ATPase compare
PP_4172 +0.7 2.7 conserved exported protein of unknown function compare
PP_0401 +0.7 1.3 Ribosomal RNA small subunit methyltransferase A compare
PP_2923 +0.7 1.7 conserved protein of unknown function compare
PP_2675 +0.7 1.6 Cytochrome c-type protein compare
PP_1733 +0.7 1.5 membrane ATPase of the MinC-MinD-MinE system compare
PP_0398 +0.7 1.3 Thiosulfate sulfurtransferase GlpE compare
PP_4836 +0.7 1.3 conserved exported protein of unknown function compare
PP_5309 +0.7 0.5 oxidative and nitrosative stress transcriptional dual regulator compare
PP_4743 +0.7 2.4 conserved protein of unknown function compare
PP_4519 +0.7 4.1 Agglutination protein compare
PP_3773 +0.7 0.9 conserved protein of unknown function compare
PP_5100 +0.7 1.6 dITP/XTP pyrophosphatase compare
PP_1570 +0.7 2.4 Head-tail adaptor compare
PP_5191 +0.7 2.1 conserved exported protein of unknown function compare
PP_4426 +0.7 1.9 Amino acid ABC transporter, permease protein compare
PP_2581 +0.7 0.7 conserved protein of unknown function compare
PP_5107 +0.7 1.7 Monofunctional biosynthetic peptidoglycan transglycosylase compare
PP_2718 +0.7 1.4 arsenic resistance transcriptional regulator compare
PP_1729 +0.7 0.9 conserved protein of unknown function compare
PP_1739 +0.7 1.3 conserved membrane protein of unknown function compare
PP_5090 +0.7 0.5 putative cell division protein compare
PP_5248 +0.7 1.0 putative hydrolase compare
PP_1068 +0.7 1.0 glutamate / aspartate ABC transporter - ATP binding subunit compare
PP_3967 +0.7 1.3 MutT/nudix family protein compare
PP_3643 +0.7 1.4 putative Oxidoreductase compare
PP_0198 +0.7 1.8 putative transporter compare
PP_3815 +0.7 2.5 Polyamine ABC transporter, permease protein compare
PP_2976 +0.7 0.5 putative transposase compare
PP_1574 +0.7 2.3 conserved protein of unknown function compare
PP_2655 +0.7 1.0 conserved protein of unknown function compare
PP_2773 +0.7 0.9 conserved protein of unknown function compare
PP_5339 +0.7 1.7 transcriptional regulator, ornithine utilization compare
PP_5331 +0.7 1.5 Long-chain acyl-CoA thioester hydrolase compare
PP_2855 +0.7 2.0 conserved exported protein of unknown function compare
PP_2895 +0.7 1.7 conserved protein of unknown function compare
PP_2661 +0.7 1.4 conserved protein of unknown function compare
PP_5472 +0.7 2.4 conserved exported protein of unknown function compare
PP_3672 +0.7 0.9 conserved protein of unknown function compare
PP_0755 +0.7 1.9 conserved protein of unknown function compare
PP_4844 +0.7 1.8 putative Urea ABC transporter, ATP-binding protein compare
PP_1268 +0.7 1.1 putative HtrA suppressor protein sohA compare
PP_2633 +0.7 1.0 conserved protein of unknown function compare
PP_2748 +0.7 0.9 putative Branched-chain amino acid ABC transporter, ATP-binding protein compare
PP_2125 +0.7 2.1 lipid kinase compare
PP_5658 +0.7 1.8 protein of unknown function compare
PP_2311 +0.7 1.2 Mg-dependent cytoplasmic DNase / RNase compare
PP_4591 +0.7 1.7 Ribonuclease D compare
PP_4793 +0.7 0.9 conserved protein of unknown function compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source Myristic acid in Pseudomonas putida KT2440

For carbon source Myristic acid across organisms