Experiment set10IT060 for Pseudomonas putida KT2440

Compare to:

1,3-Butandiol carbon source

200 most important genes:

  gene name fitness t score description  
PP_1079 -6.9 -4.7 Ornithine carbamoyltransferase compare
PP_5659 -6.7 -3.8 protein of unknown function compare
PP_0874 -6.6 -2.9 conserved protein of unknown function compare
PP_0966 -6.2 -10.4 Histidinol dehydrogenase compare
PP_0293 -6.1 -2.6 Imidazole glycerol phosphate synthase subunit HisF compare
PP_0967 -5.6 -10.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_4679 -5.5 -7.5 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1986 -5.5 -3.0 3-isopropylmalate dehydratase small subunit compare
PP_1233 -5.3 -6.5 sulfurtransferase compare
PP_1988 -5.2 -8.5 3-isopropylmalate dehydrogenase compare
PP_1826 -5.2 -2.8 Hydrolase, isochorismatase family compare
PP_4532 -5.1 -2.9 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_0184 -5.0 -3.5 Argininosuccinate lyase compare
PP_0422 -5.0 -5.3 Indole-3-glycerol phosphate synthase compare
PP_4696 -5.0 -3.4 Nitrogen regulation protein NR(I) compare
PP_0356 -4.9 -8.2 malate synthase G compare
PP_5095 -4.7 -2.3 pyrroline-5-carboxylate reductase compare
PP_1088 -4.7 -12.8 Argininosuccinate synthase compare
PP_0290 -4.7 -7.6 Imidazole glycerol phosphate synthase subunit HisH compare
PP_5185 -4.6 -6.3 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_0965 -4.6 -9.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_3198 -4.5 -2.7 Ferredoxin, 2Fe-2S compare
PP_2371 -4.5 -8.1 Sulphite reductase hemoprotein, beta subunit compare
PP_0417 -4.4 -13.9 Anthranilate synthase component 1 compare
PP_0292 -4.4 -3.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_1654 -4.4 -3.0 cysteine synthase B compare
PP_5098 -4.3 -7.1 methionine biosynthesis protein MetW compare
PP_0787 -4.3 -3.3 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_2168 -4.2 -12.0 Transaldolase compare
PP_4680 -4.2 -12.1 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1985 -4.2 -4.6 3-isopropylmalate dehydratase large subunit compare
PP_5097 -4.1 -10.3 homoserine O-acetyltransferase compare
PP_3122 -4.1 -5.3 acetoacetyl CoA-transferase (subunit A) compare
PP_4116 -4.1 -10.4 isocitrate lyase compare
PP_2001 -4.1 -8.3 O-succinylhomoserine sulfhydrylase compare
PP_1995 -4.1 -6.9 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_2327 -4.0 -6.9 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_4678 -3.8 -10.5 Ketol-acid reductoisomerase compare
PP_3505 -3.8 -2.4 conserved protein of unknown function compare
PP_3511 -3.7 -5.8 Branched-chain-amino-acid aminotransferase compare
PP_0420 -3.6 -7.8 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_4909 -3.6 -6.8 phosphoserine phosphatase compare
PP_3999 -3.6 -8.3 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_0421 -3.6 -6.0 Anthranilate phosphoribosyltransferase compare
PP_5347 -3.6 -7.9 pyruvate carboxylase subunit A compare
PP_3123 -3.5 -6.4 acetoacetyl CoA-transferase (subunit B) compare
PP_5128 -3.4 -6.5 Dihydroxy-acid dehydratase compare
PP_5248 -3.4 -1.1 putative hydrolase compare
PP_5051 -3.4 -1.6 conserved protein of unknown function compare
PP_0083 -3.4 -5.8 tryptophan synthase beta chain compare
PP_5393 -3.4 -1.2 putative metal-binding chaperone compare
PP_4700 -3.4 -2.3 pantothenate synthetase compare
PP_0691 -3.3 -3.9 Glutamate 5-kinase compare
PP_5014 -3.3 -3.3 Phosphoribosyl-AMP cyclohydrolase compare
PP_4254 -3.2 -1.5 conserved protein of unknown function compare
PP_5748 -3.2 -2.3 cytochrome c heme lyase subunit compare
PP_3532 -3.2 -1.8 Transcriptional regulator, AsnC family compare
PP_3121 -3.1 -3.6 transcriptional regulator, LysR family compare
PP_0082 -3.1 -5.1 tryptophan synthase alpha chain compare
PP_0289 -3.0 -6.2 Imidazoleglycerol-phosphate dehydratase compare
PP_4890 -3.0 -4.2 ATP phosphoribosyltransferase regulatory subunit compare
PP_1293 -3.0 -1.5 molybdopterin synthase small subunit compare
PP_3073 -3.0 -3.6 3-hydroxybutyrate dehydrogenase compare
PP_4120 -2.9 -2.0 NADH-quinone oxidoreductase subunit B compare
PP_1048 -2.9 -2.0 putative protein secretion protein for export compare
PP_4124 -2.9 -2.0 NADH-quinone oxidoreductase subunit G compare
PP_3359 -2.9 -2.0 putative Hydroxycinnamic acid degradation regulator compare
PP_4699 -2.8 -4.8 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_4993 -2.8 -4.6 Glutathione synthetase compare
PP_4122 -2.7 -1.5 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_5604 -2.7 -1.5 putative subtilisin-like serine protease compare
PP_5289 -2.6 -2.8 Acetylglutamate kinase compare
PP_1025 -2.6 -6.8 2-isopropylmalate synthase compare
PP_5495 -2.6 -2.6 protein of unknown function compare
PP_4130 -2.6 -4.5 NADH:ubiquinone oxidoreductase, membrane subunit M compare
PP_0291 -2.5 -2.5 conserved protein of unknown function compare
PP_4782 -2.4 -2.7 Phosphomethylpyrimidine kinase compare
PP_0393 -2.4 -1.6 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_4874 -2.4 -1.2 50S ribosomal protein L9 compare
PP_0735 -2.4 -1.6 molybdopterin-synthase adenylyltransferase compare
PP_4695 -2.3 -7.4 Sensory box histidine kinase compare
PP_5706 -2.3 -2.5 Sec translocation complex - SecG subunit compare
PP_3738 -2.2 -2.6 putative Transcriptional regulator VanR compare
PP_2340 -2.2 -2.8 conserved protein of unknown function compare
PP_4424 -2.2 -1.4 Uncharacterized HTH-type transcriptional regulator y4tD compare
PP_2682 -2.2 -2.4 Fe-containing alcohol dehydrogenase compare
PP_5232 -2.1 -1.5 conserved protein of unknown function compare
PP_2510 -2.1 -1.4 conserved protein of unknown function compare
PP_0959 -2.1 -1.9 phospholipid ABC transporter compare
PP_0153 -2.1 -2.0 hypothetical protein compare
PP_1664 -2.0 -3.2 phosphoribosylglycinamide formyltransferase 1 compare
PP_4121 -2.0 -3.0 NADH-quinone oxidoreductase subunit C/D compare
PP_2328 -2.0 -3.6 Phosphoadenosine phosphosulfate reductase compare
PP_5348 -2.0 -4.3 Transcriptional regulator, LysR family compare
PP_2388 -1.9 -2.6 Transporter, LysE family compare
PP_0007 -1.9 -1.6 conserved hypothetical protein compare
PP_4835 -1.9 -1.7 conserved exported protein of unknown function compare
PP_4247 -1.9 -1.4 Exonuclease compare
PP_0607 -1.9 -1.1 putative Type IV pili biogenesis protein FimT compare
PP_0401 -1.9 -2.4 Ribosomal RNA small subunit methyltransferase A compare
PP_0366 -1.9 -3.9 dethiobiotin synthetase compare
PP_1994 -1.9 -1.3 tRNA pseudouridine (38-40)synthase compare
PP_4131 -1.9 -5.4 NADH-quinone oxidoreductase subunit N compare
PP_4329 -1.8 -1.8 FlhB domain protein compare
PP_3876 -1.8 -2.3 conserved protein of unknown function compare
PP_2433 -1.8 -2.0 conserved protein of unknown function compare
PP_4895 -1.8 -3.1 tRNA dimethylallyltransferase compare
PP_4480 -1.8 -5.7 arginine N-succinyltransferase, subunit alpha compare
PP_3971 -1.7 -1.3 conserved protein of unknown function compare
PP_3649 -1.7 -2.2 Transcriptional regulator, GntR family compare
PP_t12 -1.7 -0.9 tRNA-Thr compare
PP_4098 -1.7 -1.4 UvrABC system protein C compare
PP_0313 -1.7 -1.1 putative electron transfer flavoprotein beta subunit compare
PP_2665 -1.7 -2.2 Glycerol metabolism activator compare
PP_5317 -1.6 -2.7 Probable chorismate pyruvate-lyase compare
PP_3989 -1.6 -2.2 DNA-cytosine methyltransferase compare
PP_3776 -1.6 -4.8 putative permease (RarD protein) compare
PP_0888 -1.6 -1.6 Photosynthetic apparatus regulatory protein RegA compare
PP_5000 -1.6 -1.4 peptidase component of the ATP-dependent HslVU protease compare
PP_2972 -1.6 -0.9 conserved protein of unknown function compare
PP_3286 -1.6 -2.6 DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA) compare
PP_0978 -1.6 -3.0 conserved protein of unknown function compare
PP_1207 -1.6 -2.1 conserved protein of unknown function compare
PP_3164 -1.6 -2.6 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
PP_2370 -1.5 -1.7 conserved protein of unknown function compare
PP_2923 -1.5 -1.9 conserved protein of unknown function compare
PP_3075 -1.5 -2.0 putative transcriptional regulator compare
PP_3904 -1.5 -1.5 conserved protein of unknown function compare
PP_2928 -1.5 -4.1 Saccharopine dehydrogenase compare
PP_2756 -1.5 -1.3 conserved protein of unknown function compare
PP_3508 -1.5 -2.0 Protein CobW compare
PP_1348 -1.5 -2.6 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_5598 -1.5 -1.8 conserved protein of unknown function compare
PP_5145 -1.5 -9.8 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_5028 -1.4 -3.0 proline iminopeptidase compare
PP_4005 -1.4 -3.1 Leucyl/phenylalanyl-tRNA--protein transferase compare
PP_4922 -1.4 -5.8 Phosphomethylpyrimidine synthase compare
PP_1428 -1.4 -0.8 Sigma factor AlgU negative regulatory protein compare
PP_5161 -1.4 -2.7 putative lysophospholipase compare
PP_5346 -1.4 -3.5 pyruvate carboxylase subunit B compare
PP_4129 -1.4 -2.4 NADH:ubiquinone oxidoreductase, membrane subunit L compare
PP_4779 -1.4 -7.1 AMP nucleosidase compare
PP_0361 -1.4 -1.3 putative Competence protein ComF compare
PP_4392 -1.4 -4.4 chemotaxis protein methyltransferase compare
PP_5338 -1.4 -1.7 aspartate ammonia-lyase compare
PP_2683 -1.4 -2.5 putative sensory box histidine kinase/response regulator compare
PP_1829 -1.3 -0.8 Hydrolase, alpha/beta fold family compare
PP_1783 -1.3 -0.9 dTDP-glucose pyrophosphorylase compare
PP_1099 -1.3 -1.7 Cold shock protein CapB compare
PP_2217 -1.3 -1.2 enoyl-CoA hydratase compare
PP_3052 -1.3 -1.0 conserved protein of unknown function compare
PP_5589 -1.3 -2.3 protein of unknown function containing Rhs repeat-associated core domain compare
PP_2345 -1.3 -1.3 conserved exported protein of unknown function compare
PP_4261 -1.3 -3.4 cation-transporting P-type ATPase compare
PP_2196 -1.3 -1.9 agmatinase compare
PP_5225 -1.3 -1.0 frataxin compare
PP_3037 -1.3 -1.9 C4-type zinc finger protein, DksA/TraR family compare
PP_5146 -1.3 -4.2 RNA pyrophosphohydrolase compare
PP_0195 -1.3 -1.2 conserved protein of unknown function compare
PP_1729 -1.3 -0.8 conserved protein of unknown function compare
PP_2672 -1.3 -2.3 Transcriptional activator protein ExaE compare
PP_4555 -1.3 -1.8 conserved protein of unknown function compare
PP_4726 -1.3 -1.3 Chaperone protein DnaJ compare
PP_0276 -1.2 -0.8 Transcriptional regulator, Cro/CI family compare
PP_1984 -1.2 -3.9 Transcriptional regulator, LysR family compare
PP_2581 -1.2 -1.1 conserved protein of unknown function compare
PP_3930 -1.2 -2.0 conserved exported protein of unknown function compare
PP_1906 -1.2 -2.4 ribosomal large subunit pseudouridine synthase C compare
PP_5508 -1.2 -0.9 conserved protein of unknown function compare
PP_4565 -1.2 -4.7 Isocitrate dehydrogenase kinase/phosphatase compare
PP_0248 -1.2 -4.2 Probable alpha-L-glutamate ligase compare
PP_2868 -1.2 -2.2 Transcriptional regulator, Cro/CI family compare
PP_0999 -1.2 -2.8 carbamate kinase compare
PP_0536 -1.2 -2.1 conserved protein of unknown function compare
PP_4880 -1.2 -5.2 exoribonuclease R compare
PP_3239 -1.2 -1.8 putative cointegrate resolution protein T Tn4652 compare
PP_1008 -1.2 -1.9 RNA polymerase subunit sigma-24 compare
PP_2152 -1.2 -1.3 glycerophosphoryl diester phosphodiesterase compare
PP_1231 -1.2 -2.9 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_4837 -1.2 -1.5 conserved protein of unknown function compare
PP_0135 -1.2 -2.0 conserved exported protein of unknown function compare
PP_2429 -1.1 -0.9 putative Membrane protein compare
PP_0833 -1.1 -1.1 queuine tRNA-ribosyltransferase compare
PP_1632 -1.1 -0.8 conserved protein of unknown function compare
PP_4179 -1.1 -3.7 Chaperone protein HtpG compare
PP_t13 -1.1 -1.8 tRNA-Lys compare
PP_0941 -1.1 -1.9 putative ribosome associated protein compare
PP_0365 -1.1 -3.6 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PP_4258 -1.1 -1.4 cytochrome c oxidase subunit, cbb3-type compare
PP_1649 -1.1 -1.9 D-lactate dehydrogenase compare
PP_2203 -1.1 -1.0 conserved protein of unknown function compare
PP_5582 -1.1 -0.9 conserved protein of unknown function compare
PP_2397 -1.1 -2.7 EF hand domain protein compare
PP_5085 -1.1 -2.5 malic enzyme B compare
PP_4320 -1.1 -2.7 cytochrome c-type biogenesis protein compare
PP_1057 -1.1 -2.1 Transcriptional regulator, PadR family compare
PP_2032 -1.1 -2.4 putative ATPase compare
PP_0963 -1.1 -1.0 putative BolA family protein compare
PP_4126 -1.1 -0.9 NADH-quinone oxidoreductase subunit I compare
PP_5675 -1.1 -2.1 conserved protein of unknown function compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source 1,3-Butandiol in Pseudomonas putida KT2440

For carbon source 1,3-Butandiol across organisms