Experiment set10IT060 for Pseudomonas putida KT2440

Compare to:

1,3-Butandiol carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_0406 +3.5 22.6 Nucleotidyltransferase family protein compare
PP_1778 +3.0 12.2 Lipopolysaccharide ABC export system, permease protein compare
PP_1111 +2.9 14.5 putative Synthetase compare
PP_1224 +2.9 12.5 periplasmic subunit of the TolQRA transport system compare
PP_4994 +2.9 14.0 conserved protein of unknown function compare
PP_0938 +2.8 17.4 conserved protein of unknown function compare
PP_1779 +2.7 12.0 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_1898 +2.6 11.0 MotA/TolQ/ExbB proton channel family protein compare
PP_1719 +2.6 16.2 Tail-specific protease prc compare
PP_1109 +2.4 17.0 Transcriptional regulator, GntR family compare
PP_1430 +2.4 17.2 putative periplasmic serine endoprotease DegP-like compare
PP_1110 +2.2 6.9 serine acetyltransferase compare
PP_4943 +2.0 3.4 putative Glycosyl transferase compare
PP_1623 +1.8 11.6 RNA polymerase, sigma S (sigma 38) factor compare
PP_3821 +1.8 10.6 UTP-glucose-1-phosphate uridylyltransferase compare
PP_5350 +1.8 5.1 Transcriptional regulator, RpiR family compare
PP_0852 +1.7 4.2 Transcriptional regulator, Cro/CI family compare
PP_2307 +1.7 2.3 conserved protein of unknown function compare
PP_1584 +1.6 8.9 conserved protein of unknown function compare
PP_2820 +1.6 1.7 HTH-type transcriptional regulator nfxB compare
PP_4940 +1.6 7.7 Putative glycosyltransferase compare
PP_3637 +1.6 2.2 putative Sulfonate ABC transporter, ATP-binding protein compare
PP_0630 +1.5 1.9 DNA gyrase inhibitor YacG compare
PP_4785 +1.5 7.5 conserved exported protein of unknown function compare
PP_4004 +1.5 5.0 DNA translocase FtsK compare
PP_1562 +1.5 2.5 putative Phage terminase, small subunit compare
PP_4964 +1.5 3.3 D-erythrose 4-phosphate dehydrogenase compare
PP_0377 +1.5 3.6 coenzyme PQQ synthesis protein D compare
PP_0962 +1.5 2.8 toluene-tolerance protein compare
PP_5610 +1.3 2.4 protein of unknown function compare
PP_2403 +1.3 2.1 Chemotaxis protein CheY compare
PP_1560 +1.3 6.8 conserved protein of unknown function compare
PP_2499 +1.3 1.8 conserved protein of unknown function compare
PP_5475 +1.3 1.0 conserved protein of unknown function compare
PP_2748 +1.3 1.9 putative Branched-chain amino acid ABC transporter, ATP-binding protein compare
PP_4561 +1.2 1.4 stress response protein compare
PP_0123 +1.2 5.1 DNA polymerase I, 5 compare
PP_1573 +1.2 4.1 putative Major tail protein compare
PP_4058 +1.2 7.5 1,4-alpha-glucan branching enzyme compare
PP_0376 +1.2 6.4 Coenzyme PQQ synthesis protein E compare
PP_1764 +1.1 5.6 Phosphoglycolate phosphatase 2 compare
PP_5575 +1.1 1.5 conserved protein of unknown function compare
PP_1742 +1.1 3.5 conserved inner membrane protein of unknown function compare
PP_5476 +1.1 4.7 conserved protein of unknown function compare
PP_2090 +1.1 2.9 Uroporphyrinogen-III C-methyltransferase compare
PP_5191 +1.1 1.7 conserved exported protein of unknown function compare
PP_3365 +1.1 1.3 Acetolactate synthase compare
PP_3899 +1.1 1.9 conserved protein of unknown function, hicB family compare
PP_5230 +1.1 2.1 Tyrosine recombinase XerC compare
PP_4204 +1.1 3.1 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor compare
PP_1217 +1.1 2.3 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_2999 +1.1 1.0 Glyoxalase family protein compare
PP_1572 +1.1 5.8 conserved protein of unknown function compare
PP_1568 +1.1 1.3 conserved protein of unknown function compare
PP_3757 +1.1 2.7 Chemotaxis protein CheY compare
PP_4936 +1.1 5.0 O-antigen polymerase compare
PP_4054 +1.1 2.0 conserved protein of unknown function compare
PP_4213 +1.1 1.5 putative dipeptidase compare
PP_2844 +1.1 2.8 Urease subunit beta compare
PP_3614 +1.1 1.8 conserved membrane protein of unknown function compare
PP_2680 +1.0 3.7 aldehyde dehydrogenase compare
PP_1569 +1.0 3.3 conserved protein of unknown function compare
PP_1578 +1.0 4.3 conserved protein of unknown function compare
PP_1468 +1.0 2.3 Tyrosine recombinase XerD compare
PP_1799 +1.0 7.6 GDP-mannose 4,6-dehydratase compare
PP_1804 +1.0 5.6 Glycosyl transferase WbpL compare
PP_3926 +1.0 1.6 short-chain dehydrogenase compare
PP_0022 +1.0 1.1 hypothetical protein compare
PP_1153 +1.0 1.5 putative lipoprotein compare
PP_1774 +1.0 2.9 conserved exported protein of unknown function compare
PP_3258 +1.0 1.4 conserved protein of unknown function compare
PP_1800 +1.0 5.8 Oxidoreductase Rmd compare
PP_0801 +1.0 1.3 conserved exported protein of unknown function compare
PP_4136 +1.0 0.6 Transcriptional regulator, LuxR family compare
PP_1563 +1.0 6.6 putative Phage terminase, large subunit compare
PP_4482 +1.0 2.9 Transcriptional regulator, AraC family compare
PP_5337 +1.0 3.1 LysR family transcriptional regulator compare
PP_0379 +1.0 3.3 Coenzyme PQQ synthesis protein B compare
PP_0345 +1.0 2.4 putative Heptose kinase WapP compare
PP_4836 +0.9 1.7 conserved exported protein of unknown function compare
PP_1574 +0.9 3.1 conserved protein of unknown function compare
PP_1570 +0.9 1.8 Head-tail adaptor compare
PP_2745 +0.9 1.5 Universal stress protein family compare
PP_1577 +0.9 6.7 Phage tail tape meausure protein, lambda family compare
PP_4871 +0.9 2.9 putative lysine decarboxylase family protein compare
PP_1556 +0.9 1.6 conserved protein of unknown function compare
PP_5701 +0.9 1.0 conserved protein of unknown function compare
PP_1564 +0.9 2.8 conserved exported protein of unknown function compare
PP_2322 +0.9 4.7 Major outer membrane lipoprotein compare
PP_1206 +0.9 3.8 basic-amino-acid specific porin OprD compare
PP_1776 +0.9 7.0 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_1777 +0.9 4.9 phosphomannomutase compare
PP_1565 +0.9 4.7 Phage portal protein, HK97 family compare
PP_4356 +0.9 3.1 Flagellar protein FliO compare
PP_1780 +0.9 7.5 putative mannosyltransferase compare
PP_4828 +0.9 0.6 Precorrin-8X methylmutase compare
PP_3597 +0.9 2.2 L-lysine and D-lysine ABC transporter, ATPase component (from data) compare
PP_0378 +0.9 3.7 Pyrroloquinoline-quinone synthase compare
PP_1561 +0.8 2.3 putative Phage holin compare
PP_3685 +0.8 2.3 conserved protein of unknown function compare
PP_5528 +0.8 1.6 conserved protein of unknown function compare
PP_3748 +0.8 1.8 conserved hypothetical protein compare
PP_3002 +0.8 2.2 shikimate dehydrogenase-related enzyme compare
PP_0181 +0.8 2.6 conserved protein of unknown function compare
PP_2878 +0.8 1.7 conserved protein of unknown function compare
PP_5324 +0.8 1.9 Response regulator compare
PP_2046 +0.8 1.5 Transcriptional regulator, LysR family compare
PP_2883 +0.8 1.6 conserved protein of unknown function compare
PP_4739 +0.8 2.0 conserved protein of unknown function compare
PP_1186 +0.8 1.1 two component system DNA-binding transcriptional dual regulator compare
PP_0254 +0.8 1.5 conserved protein of unknown function compare
PP_4938 +0.8 3.8 putative Glycosyl transferase compare
PP_5705 +0.8 1.0 protein of unknown function compare
PP_1579 +0.8 5.7 conserved protein of unknown function compare
PP_1548 +0.8 1.1 conserved protein of unknown function compare
PP_1805 +0.8 6.6 Polysaccharide biosynthesis protein compare
PP_5267 +0.8 0.8 putative cytochrome c5 compare
PP_1482 +0.8 2.2 polyamine ABC transporter, permease protein compare
PP_3875 +0.8 2.2 conserved protein of unknown function compare
PP_4504 +0.8 1.4 conserved exported protein of unknown function compare
PP_1580 +0.8 4.4 conserved protein of unknown function compare
PP_1576 +0.8 3.9 putative Immunity protein compare
PP_4073 +0.8 1.0 conserved exported protein of unknown function compare
PP_3411 +0.8 0.8 conserved protein of unknown function compare
PP_5609 +0.8 2.5 conserved protein of unknown function compare
PP_1962 +0.8 3.3 Site-specific recombinase, phage integrase family compare
PP_1451 +0.8 2.3 conserved exported protein of unknown function compare
PP_4917 +0.8 1.6 3',5'-cyclic-nucleotide phosphodiesterase compare
PP_2320 +0.8 5.4 conserved exported protein of unknown function compare
PP_1581 +0.8 5.3 BNR domain protein compare
PP_0240 +0.8 1.7 Aliphatic sulfonates import ATP-binding protein SsuB compare
PP_1802 +0.8 5.8 glycosyl transferase compare
PP_5042 +0.8 2.3 conserved protein of unknown function compare
PP_1903 +0.7 2.8 putative phosphotyrosine-protein phosphatase compare
PP_4769 +0.7 1.5 conserved protein of unknown function compare
PP_0725 +0.7 2.7 conserved hypothetical TPR repeat protein compare
PP_1097 +0.7 0.7 Methionine--tRNA ligase compare
PP_2409 +0.7 1.8 cobalt-zinc-cadmium resistance protein compare
PP_0080 +0.7 2.7 conserved protein of unknown function compare
PP_1325 +0.7 2.5 putative lipoprotein compare
PP_1567 +0.7 3.0 Capsid protein compare
PP_1204 +0.7 2.2 putative Lipoprotein compare
PP_3551 +0.7 1.2 DNA-binding response regulator, LuxR family compare
PP_5017 +0.7 1.0 Sec-independent protein translocase protein TatB compare
PP_4233 +0.7 1.9 putative Oxidoreductase, small subunit compare
PP_1215 +0.7 0.5 Crossover junction endodeoxyribonuclease RuvC compare
PP_2965 +0.7 2.8 putative tnpA repressor TnpC compare
PP_1538 +0.7 3.2 conserved protein of unknown function compare
PP_1218 +0.7 1.7 putative acyl-CoA thioesterase compare
PP_4207 +0.7 2.0 conserved protein of unknown function compare
PP_0137 +0.7 3.6 glutamate/aspartate-proton DAACS transporter compare
PP_1258 +0.7 2.2 4-hydroxyproline epimerase compare
PP_1801 +0.7 4.9 Glycosyl transferase WbpY compare
PP_0679 +0.7 2.1 conserved exported protein of unknown function compare
PP_2127 +0.7 1.0 Sensor histidine kinase compare
PP_1582 +0.7 4.8 conserved protein of unknown function compare
PP_0274 +0.7 1.1 putative transcriptional regulator containing HTH domain compare
PP_2766 +0.7 1.8 Long-chain-fatty-acid--CoA ligase-related protein compare
PP_4171 +0.7 5.3 conserved exported protein of unknown function compare
PP_2280 +0.7 1.0 conserved protein of unknown function compare
PP_4707 +0.7 1.2 OsmY-related protein compare
PP_0490 +0.7 2.3 formate dehydrogenase-O, beta subunit compare
PP_1647 +0.7 1.9 conserved protein of unknown function compare
PP_5345 +0.7 2.4 Acetyltransferase, GNAT family compare
PP_4985 +0.7 2.1 16S rRNA m3U1498 methyltransferase compare
PP_5522 +0.6 2.1 protein of unknown function compare
PP_1268 +0.6 1.3 putative HtrA suppressor protein sohA compare
PP_3969 +0.6 1.7 Response regulator compare
PP_5473 +0.6 1.3 putative transcriptional regulator, LuxR family compare
PP_5561 +0.6 2.7 conserved protein of unknown function compare
PP_1628 +0.6 1.5 NMN amidohydrolase compare
PP_4682 +0.6 1.8 conserved protein of unknown function containing tetratricopeptide repeat domain compare
PP_5272 +0.6 2.5 conserved protein of unknown function compare
PP_1571 +0.6 1.2 conserved protein of unknown function compare
PP_3314 +0.6 1.9 Heat shock protein, HSP20 family compare
PP_0692 +0.6 1.8 conserved protein of unknown function compare
PP_1442 +0.6 1.8 conserved protein of unknown function compare
PP_0834 +0.6 0.6 Sec translocation complex subunit YajC compare
PP_5500 +0.6 0.9 protein of unknown function compare
PP_5058 +0.6 2.5 Carboxy-terminal-processing protease compare
PP_2067 +0.6 1.6 putative EmrB/QacA family drug resistance transporter compare
PP_0405 +0.6 5.3 conserved protein of unknown function compare
PP_2387 +0.6 1.0 conserved protein of unknown function compare
PP_5658 +0.6 0.8 protein of unknown function compare
PP_0054 +0.6 1.9 conserved membrane protein of unknown function compare
PP_2412 +0.6 3.1 ParA family protein compare
PP_3374 +0.6 1.9 conserved protein of unknown function compare
PP_5583 +0.6 1.1 conserved protein of unknown function compare
PP_5676 +0.6 2.9 conserved protein of unknown function compare
PP_0678 +0.6 3.1 conserved exported protein of unknown function compare
PP_4911 +0.6 1.9 conserved protein of unknown function compare
PP_1427 +0.6 2.9 RNA polymerase sigma E factor compare
PP_4273 +0.6 0.7 Transcriptional regulator, MerR family compare
PP_4156 +0.6 1.2 Transcriptional regulator, LysR family compare
PP_5717 +0.6 1.0 conserved protein of unknown function compare
PP_2895 +0.6 2.2 conserved protein of unknown function compare
PP_5125 +0.6 1.9 Formamidopyrimidine-DNA glycosylase compare
PP_2631 +0.6 0.9 putative cellulose biosynthesis, BcsF/YhjT compare
PP_4640 +0.6 2.2 conserved protein of unknown function compare
PP_0435 +0.6 4.1 Peptidase, M23/M37 family compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source 1,3-Butandiol in Pseudomonas putida KT2440

For carbon source 1,3-Butandiol across organisms