Experiment set10IT048 for Pseudomonas putida KT2440

Compare to:

D-Mannose carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1018 +2.1 15.6 mannose/glucose ABC transporter - ATP binding subunit conserved
PP_1016 +2.1 14.9 mannose/glucose ABC transporter, permease protein conserved
PP_1012 +2.0 13.2 DNA-binding response regulator compare
PP_1015 +2.0 12.0 mannose/glucose ABC transporter, glucose-binding periplasmic protein conserved
PP_1017 +2.0 11.7 mannose/glucose ABC transporter, permease protein conserved
PP_2568 +1.5 2.7 Ring-cleaving dioxygenase compare
PP_1013 +1.5 10.3 Sensor histidine kinase conserved
PP_5145 +1.5 14.3 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0547 +1.4 6.8 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_1021 +1.3 8.8 DNA-binding transcriptional regulator compare
PP_1609 +1.3 5.1 conserved protein of unknown function compare
PP_3924 +1.3 6.4 conserved protein of unknown function compare
PP_0792 +1.3 4.5 catabolite repressor-activator, DNA-binding transcriptional dual regulator compare
PP_4902 +1.2 3.1 Oligoribonuclease compare
PP_2510 +1.2 2.8 conserved protein of unknown function compare
PP_1912 +1.1 5.0 Phosphate acyltransferase compare
PP_1906 +1.1 4.2 ribosomal large subunit pseudouridine synthase C compare
PP_1110 +1.0 3.1 serine acetyltransferase compare
PP_5248 +1.0 2.0 putative hydrolase compare
PP_5146 +1.0 5.3 RNA pyrophosphohydrolase compare
PP_0594 +1.0 7.3 Transcriptional regulator, TetR family compare
PP_4942 +0.9 2.3 conserved protein of unknown function compare
PP_1445 +0.9 4.7 carbohydrate-selective porin compare
PP_4891 +0.9 4.4 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex compare
PP_1269 +0.9 1.4 Universal stress protein family compare
PP_5337 +0.9 4.2 LysR family transcriptional regulator compare
PP_4892 +0.8 4.9 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex compare
PP_0948 +0.8 3.2 Phosphocarrier protein HPr compare
PP_2972 +0.8 2.7 conserved protein of unknown function compare
PP_4961 +0.8 1.3 putative Lipoprotein compare
PP_0022 +0.8 1.4 hypothetical protein compare
PP_1109 +0.8 6.3 Transcriptional regulator, GntR family compare
PP_4050 +0.8 7.1 glycogen synthase compare
PP_2889 +0.8 3.2 putative Transmembrane regulator PrtR compare
PP_2499 +0.8 1.3 conserved protein of unknown function compare
PP_4367 +0.8 2.6 Flagellar assembly protein FliH compare
PP_3637 +0.8 1.5 putative Sulfonate ABC transporter, ATP-binding protein compare
PP_4682 +0.7 3.4 conserved protein of unknown function containing tetratricopeptide repeat domain compare
PP_5428 +0.7 3.5 conserved exported protein of unknown function compare
PP_0001 +0.7 1.1 probable chromosome-partitioning protein compare
PP_2457 +0.7 4.8 DNA-binding transcriptional repressor compare
PP_2999 +0.7 1.1 Glyoxalase family protein compare
PP_4699 +0.7 2.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_1214 +0.7 1.6 putative transcriptional regulatory protein compare
PP_4981 +0.7 1.6 polyisoprene-binding protein, acidic stress response factor compare
PP_1568 +0.7 1.3 conserved protein of unknown function compare
PP_3810 +0.7 1.2 conserved protein of unknown function compare
PP_1236 +0.7 4.4 putative Glycine cleavage system transcriptional repressor compare
PP_4273 +0.7 0.9 Transcriptional regulator, MerR family compare
PP_3415 +0.7 4.8 Transcriptional regulator, LacI family compare
PP_0191 +0.7 1.8 Transcriptional regulatory protein AlgQ compare
PP_0138 +0.7 5.1 conserved membrane protein of unknown function compare
PP_2341 +0.7 1.6 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_5445 +0.7 1.5 conserved protein of unknown function compare
PP_1716 +0.7 2.7 Transcriptional regulator, Cro/CI family compare
PP_4394 +0.7 3.4 flagella basal body P-ring formation protein compare
PP_1623 +0.7 5.1 RNA polymerase, sigma S (sigma 38) factor compare
PP_4356 +0.7 3.1 Flagellar protein FliO compare
PP_4036 +0.7 3.9 D-hydantoinase/dihydropyrimidinase compare
PP_0685 +0.6 2.1 conserved protein of unknown function compare
PP_3519 +0.6 1.3 putative Lipoprotein compare
PP_4944 +0.6 2.7 Carbamoyltransferase compare
PP_4391 +0.6 4.9 flagellar basal-body rod protein FlgB compare
PP_1408 +0.6 4.0 (R)-3-hydroxydecanoyl-ACP:CoA transacylase compare
PP_1307 +0.6 3.6 AsnC family transcriptional regulator compare
PP_1294 +0.6 2.1 molybdopterin synthase large subunit compare
PP_0236 +0.6 1.6 NAD(P)H-dependent FMN reductase subunit compare
PP_0540 +0.6 3.6 conserved inner membrane protein compare
PP_5003 +0.6 5.1 poly(3-hydroxyalkanoate) polymerase 1 compare
PP_1803 +0.6 5.2 UDP-sugar epimerase compare
PP_0007 +0.6 1.5 conserved hypothetical protein compare
PP_0393 +0.6 1.5 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_4370 +0.6 3.5 Flagellar hook-basal body complex protein FliE compare
PP_2748 +0.6 2.1 putative Branched-chain amino acid ABC transporter, ATP-binding protein compare
PP_3449 +0.6 2.5 conserved exported protein of unknown function compare
PP_3480 +0.6 2.0 conserved protein of unknown function compare
PP_4389 +0.6 3.8 Flagellar basal-body rod modification protein FlgD compare
PP_2455 +0.6 2.8 ribose ABC transporter - ATP-binding subunit compare
PP_3580 +0.6 2.1 conserved protein of unknown function compare
PP_5689 +0.6 1.8 conserved protein of unknown function compare
PP_3551 +0.6 1.4 DNA-binding response regulator, LuxR family compare
PP_1548 +0.6 1.7 conserved protein of unknown function compare
PP_4386 +0.6 4.4 flagellar basal-body rod protein FlgF compare
PP_0959 +0.6 1.0 phospholipid ABC transporter compare
PP_4037 +0.6 4.8 NADP-dependent dihydropyrimidine dehydrogenase subunit compare
PP_4365 +0.6 3.6 Flagellar protein FliJ compare
PP_3441 +0.6 3.7 conserved protein of unknown function compare
PP_4361 +0.6 2.8 Flagellar hook-length control protein FliK compare
PP_0640 +0.6 2.7 conserved protein of unknown function compare
PP_4373 +0.6 4.7 Transcriptional regulator FleQ compare
PP_1826 +0.6 1.3 Hydrolase, isochorismatase family compare
PP_4591 +0.6 2.5 Ribonuclease D compare
PP_0848 +0.6 1.6 donor of Fe2+ and regulator of cysteine desulfurase activity compare
PP_4917 +0.6 1.9 3',5'-cyclic-nucleotide phosphodiesterase compare
PP_4561 +0.5 0.9 stress response protein compare
PP_1787 +0.5 2.5 conserved protein of unknown function compare
PP_2745 +0.5 2.2 Universal stress protein family compare
PP_5106 +0.5 2.1 conserved inner membrane protein compare
PP_0881 +0.5 2.5 dipeptide ABC transporter - putative membrane subunit compare
PP_2738 +0.5 1.7 putative Transcriptional regulator compare
PP_4379 +0.5 2.5 Beta-ketoacyl-acyl-carrier-protein synthase I compare
PP_0937 +0.5 2.7 endoribonuclease G (RNAse G) compare
PP_2459 +0.5 1.5 ribose pyranase compare
PP_2309 +0.5 0.9 conserved protein of unknown function compare
PP_2173 +0.5 3.2 Transcriptional regulator, AraC family compare
PP_5580 +0.5 1.6 protein of unknown function compare
PP_1386 +0.5 3.4 Probable efflux pump periplasmic linker TtgA compare
PP_2335 +0.5 3.1 methylcitrate synthase compare
PP_2388 +0.5 2.1 Transporter, LysE family compare
PP_2144 +0.5 2.1 Transcriptional regulator, TetR family compare
PP_3052 +0.5 1.0 conserved protein of unknown function compare
PP_4385 +0.5 2.6 flagellar basal-body rod protein FlgG compare
PP_2970 +0.5 1.9 conserved exported protein of unknown function compare
PP_3097 +0.5 3.3 conserved protein of unknown function compare
PP_0846 +0.5 0.9 DnaK-like molecular chaperone specific for IscU compare
PP_4354 +0.5 1.5 flagellar export apparatus subunit compare
PP_3840 +0.5 1.0 conserved protein of unknown function compare
PP_4388 +0.5 4.0 Flagellar hook protein FlgE compare
PP_1779 +0.5 2.6 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_2835 +0.5 2.1 putative oxidoreductase compare
PP_2449 +0.5 2.3 conserved protein of unknown function compare
PP_2379 +0.5 1.8 putative cytochrome oxidase biogenesis protein compare
PP_4396 +0.5 2.1 conserved protein of unknown function compare
PP_1564 +0.5 2.6 conserved exported protein of unknown function compare
PP_1067 +0.5 4.0 Sensor histidine kinase compare
PP_2087 +0.5 1.4 CmpX protein compare
PP_2697 +0.5 2.0 putative oxidoreductase containing a flavin reductase domain compare
PP_3509 +0.5 2.2 Glyoxalase family protein compare
PP_4787 +0.5 2.0 putative protein with nucleoside triphosphate hydrolase domain compare
PP_4390 +0.5 3.0 flagellar basal-body rod protein FlgC compare
PP_4739 +0.5 1.9 conserved protein of unknown function compare
PP_3522 +0.5 1.6 conserved protein of unknown function compare
PP_5519 +0.5 2.0 conserved protein of unknown function of phage origin compare
PP_3821 +0.5 2.9 UTP-glucose-1-phosphate uridylyltransferase compare
PP_5317 +0.5 1.2 Probable chorismate pyruvate-lyase compare
PP_0398 +0.5 2.1 Thiosulfate sulfurtransferase GlpE compare
PP_0801 +0.5 0.9 conserved exported protein of unknown function compare
PP_5152 +0.5 2.0 conserved exported protein of unknown function compare
PP_5241 +0.5 1.4 DNA-binding response regulator, LuxR family compare
PP_4289 +0.5 3.6 conserved membrane protein of unknown function compare
PP_4940 +0.5 2.5 Putative glycosyltransferase compare
PP_2681 +0.5 1.3 coenzyme PQQ synthesis protein D compare
PP_1262 +0.5 3.6 LysR family transcriptional regulator compare
PP_3481 +0.5 1.1 conserved exported protein of unknown function compare
PP_4054 +0.5 0.8 conserved protein of unknown function compare
PP_3243 +0.5 1.5 Acetyltransferase, GNAT family compare
PP_3903 +0.4 0.9 conserved protein of unknown function compare
PP_5167 +0.4 1.9 conserved hypothetical protein compare
PP_3634 +0.4 1.8 putative acetyltransferase, GNAT family compare
PP_4352 +0.4 3.3 flagellin export apparatus, substrate specificity protein compare
PP_4038 +0.4 2.5 Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) compare
PP_2320 +0.4 3.8 conserved exported protein of unknown function compare
PP_4413 +0.4 2.4 conserved protein of unknown function compare
PP_3460 +0.4 0.9 quinohemoprotein amine dehydrogenase, gamma subunit compare
PP_5667 +0.4 1.3 putative microcin B17-like-processing protein, McbC family compare
PP_4382 +0.4 3.2 Peptidoglycan hydrolase FlgJ compare
PP_3943 +0.4 3.2 N-formylmaleamate deformylase compare
PP_5500 +0.4 1.1 protein of unknown function compare
PP_0306 +0.4 1.9 conserved protein of unknown function compare
PP_1454 +0.4 1.4 conserved protein of unknown function compare
PP_1111 +0.4 2.1 putative Synthetase compare
PP_0566 +0.4 0.6 translation-related factor compare
PP_5007 +0.4 0.9 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_0355 +0.4 1.7 Response regulator compare
PP_4556 +0.4 2.0 conserved protein of unknown function compare
PP_1028 +0.4 1.9 Transcriptional regulator, LysR family compare
PP_0904 +0.4 3.2 InaA protein compare
PP_4348 +0.4 1.6 putative Cystathionine beta-lyase compare
PP_4143 +0.4 1.8 conserved protein of unknown function compare
PP_0202 +0.4 1.7 CBS domain-containing protein compare
PP_0574 +0.4 3.3 DNA-binding response regulator, LuxR family compare
PP_5357 +0.4 2.6 Pyridoxamine kinase compare
PP_3353 +0.4 1.5 putative sulfatase-modifying factor (C-alpha-formyglycine- generating enzyme) compare
PP_0797 +0.4 2.4 conserved protein of unknown function compare
PP_3908 +0.4 1.1 conserved protein of unknown function compare
PP_5597 +0.4 1.4 conserved protein of unknown function compare
PP_4786 +0.4 2.2 conserved protein of unknown function compare
PP_t10 +0.4 1.1 tRNA-Pro compare
PP_3314 +0.4 1.6 Heat shock protein, HSP20 family compare
PP_1459 +0.4 2.2 CBS domain protein compare
PP_0135 +0.4 1.7 conserved exported protein of unknown function compare
PP_0195 +0.4 1.3 conserved protein of unknown function compare
PP_5338 +0.4 1.2 aspartate ammonia-lyase compare
PP_5514 +0.4 1.5 conserved protein of unknown function compare
PP_2323 +0.4 3.3 conserved protein of unknown function compare
PP_1903 +0.4 1.5 putative phosphotyrosine-protein phosphatase compare
PP_1255 +0.4 1.7 putative cis-4-hydroxy-D-proline oxidase compare
PP_2976 +0.4 1.0 putative transposase compare
PP_2575 +0.4 1.3 conserved exported protein of unknown function compare
PP_4937 +0.4 1.2 toluene tolerance protein compare
PP_5600 +0.4 1.3 conserved protein of unknown function compare
PP_2023 +0.4 1.8 Glutathione S-transferase family protein compare
PP_2074 +0.4 1.7 Transcriptional regulator, LysR family compare
PP_4018 +0.4 1.2 Acetyltransferase, GNAT family compare
PP_5223 +0.4 1.9 regulator of nucleotide diphosphokinase compare
PP_2152 +0.4 1.2 glycerophosphoryl diester phosphodiesterase compare
PP_4824 +0.4 2.1 Sensor histidine kinase/response regulator compare
PP_4384 +0.4 3.1 Flagellar L-ring protein compare
PP_4418 +0.4 1.9 conserved protein of unknown function compare
PP_4946 +0.4 2.9 sodium/L-proline transporter compare


Specific Phenotypes

For 13 genes in this experiment

For carbon source D-Mannose in Pseudomonas putida KT2440

For carbon source D-Mannose across organisms