Experiment set10IT047 for Pseudomonas putida KT2440

Compare to:

Sodium pyruvate carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_4734 +6.3 47.6 DNA-binding transcriptional dual regulator, LldR-L-lactate compare
PP_5313 +4.0 18.8 DNA-binding protein HU-alpha compare
PP_1778 +2.1 10.7 Lipopolysaccharide ABC export system, permease protein compare
PP_0406 +2.0 14.6 Nucleotidyltransferase family protein compare
PP_5058 +2.0 10.1 Carboxy-terminal-processing protease compare
PP_1779 +1.9 9.3 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_1224 +1.9 10.4 periplasmic subunit of the TolQRA transport system compare
PP_4004 +1.8 8.0 DNA translocase FtsK compare
PP_4799 +1.8 7.9 putative Muramoyltetrapeptide carboxypeptidase compare
PP_1623 +1.7 10.9 RNA polymerase, sigma S (sigma 38) factor compare
PP_0540 +1.6 10.2 conserved inner membrane protein compare
PP_1468 +1.6 3.4 Tyrosine recombinase XerD compare
PP_0833 +1.6 2.9 queuine tRNA-ribosyltransferase compare
PP_2999 +1.5 2.3 Glyoxalase family protein compare
PP_5230 +1.5 5.1 Tyrosine recombinase XerC compare
PP_2568 +1.4 2.1 Ring-cleaving dioxygenase compare
PP_0547 +1.4 6.6 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_3132 +1.3 9.5 putative Polysaccharide transporter compare
PP_3245 +1.3 1.1 conserved protein of unknown function compare
PP_0138 +1.3 8.7 conserved membrane protein of unknown function compare
PP_1563 +1.3 9.0 putative Phage terminase, large subunit compare
PP_1217 +1.3 4.7 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_3198 +1.2 4.0 Ferredoxin, 2Fe-2S compare
PP_1574 +1.2 4.9 conserved protein of unknown function compare
PP_1568 +1.2 2.0 conserved protein of unknown function compare
PP_1565 +1.2 7.1 Phage portal protein, HK97 family compare
PP_4994 +1.2 5.1 conserved protein of unknown function compare
PP_4910 +1.1 2.4 conserved protein of unknown function compare
PP_0630 +1.1 1.8 DNA gyrase inhibitor YacG compare
PP_1430 +1.1 7.3 putative periplasmic serine endoprotease DegP-like compare
PP_0232 +1.1 2.3 ATP-binding taurine transporter subunit compare
PP_4642 +1.1 1.9 Cyclic diguanosine monophosphate-binding protein compare
PP_1561 +1.1 4.5 putative Phage holin compare
PP_1564 +1.1 4.5 conserved exported protein of unknown function compare
PP_3318 +1.1 1.9 conserved protein of unknown function compare
PP_2972 +1.0 2.0 conserved protein of unknown function compare
PP_1570 +1.0 4.0 Head-tail adaptor compare
PP_4254 +1.0 2.8 conserved protein of unknown function compare
PP_1562 +1.0 3.0 putative Phage terminase, small subunit compare
PP_1208 +1.0 1.5 conserved protein of unknown function, SlyX family compare
PP_1571 +1.0 3.9 conserved protein of unknown function compare
PP_0513 +1.0 2.0 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP compare
PP_1560 +1.0 3.1 conserved protein of unknown function compare
PP_3880 +1.0 2.0 conserved exported protein of unknown function compare
PP_5338 +1.0 2.3 aspartate ammonia-lyase compare
PP_1553 +1.0 2.5 conserved protein of unknown function compare
PP_1567 +1.0 5.5 Capsid protein compare
PP_0001 +1.0 1.0 probable chromosome-partitioning protein compare
PP_0123 +1.0 4.7 DNA polymerase I, 5 compare
PP_1186 +0.9 2.2 two component system DNA-binding transcriptional dual regulator compare
PP_5572 +0.9 2.0 protein of unknown function compare
PP_5191 +0.9 1.3 conserved exported protein of unknown function compare
PP_4099 +0.9 9.0 two-componenent system BarA/UvrY - regulatory subunit compare
PP_4273 +0.9 1.7 Transcriptional regulator, MerR family compare
PP_1898 +0.9 3.4 MotA/TolQ/ExbB proton channel family protein compare
PP_1573 +0.9 4.3 putative Major tail protein compare
PP_0725 +0.9 3.9 conserved hypothetical TPR repeat protein compare
PP_0025 +0.9 1.7 hypothetical protein compare
PP_1566 +0.9 5.5 Peptidase U35 compare
PP_1294 +0.9 3.0 molybdopterin synthase large subunit compare
PP_4942 +0.9 1.8 conserved protein of unknown function compare
PP_1543 +0.9 3.4 conserved protein of unknown function compare
PP_t29 +0.9 1.8 tRNA-Ala compare
PP_4555 +0.8 2.9 conserved protein of unknown function compare
PP_4356 +0.8 2.5 Flagellar protein FliO compare
PP_1578 +0.8 5.1 conserved protein of unknown function compare
PP_1215 +0.8 1.3 Crossover junction endodeoxyribonuclease RuvC compare
PP_3307 +0.8 2.3 conserved protein of unknown function compare
PP_4156 +0.8 2.6 Transcriptional regulator, LysR family compare
PP_5054 +0.8 1.5 glutaredoxin 3 compare
PP_0832 +0.8 2.5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
PP_1216 +0.8 1.6 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_1650 +0.8 7.8 Sensor protein GacS compare
PP_5471 +0.8 1.9 putative response regulator receiver protein compare
PP_1309 +0.8 4.0 conserved exported protein of unknown function compare
PP_4936 +0.8 3.8 O-antigen polymerase compare
PP_4697 +0.8 2.2 poly(A) polymerase compare
PP_5225 +0.8 1.6 frataxin compare
PP_0153 +0.8 1.6 hypothetical protein compare
PP_1577 +0.8 6.1 Phage tail tape meausure protein, lambda family compare
PP_3908 +0.8 1.8 conserved protein of unknown function compare
PP_3137 +0.8 4.9 Glycosyl transferase, group 2 family protein compare
PP_0856 +0.8 2.5 conserved lipoprotein of unknown function compare
PP_1580 +0.8 4.3 conserved protein of unknown function compare
PP_2615 +0.8 2.5 hemolysin-coregulated protein compare
PP_2738 +0.8 3.0 putative Transcriptional regulator compare
PP_0236 +0.7 1.6 NAD(P)H-dependent FMN reductase subunit compare
PP_1364 +0.7 5.2 conserved exported protein of unknown function compare
PP_4897 +0.7 2.9 N-acetylmuramoyl-L-alanine amidase compare
PP_1787 +0.7 2.3 conserved protein of unknown function compare
PP_5472 +0.7 3.3 conserved exported protein of unknown function compare
PP_1548 +0.7 1.0 conserved protein of unknown function compare
PP_1198 +0.7 2.7 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_4546 +0.7 2.5 ATP-dependent helicase HrpA compare
PP_4470 +0.7 2.4 putative transcriptional regulator (Arc domain-containing) compare
PP_1579 +0.7 5.5 conserved protein of unknown function compare
PP_2254 +0.7 2.9 Transcriptional regulator, GntR family compare
PP_5448 +0.7 2.0 conserved protein of unknown function compare
PP_1734 +0.7 2.0 Probable septum site-determining protein MinC compare
PP_5475 +0.7 1.1 conserved protein of unknown function compare
PP_1581 +0.7 5.2 BNR domain protein compare
PP_0354 +0.7 4.8 CBS domain protein compare
PP_5090 +0.7 1.8 putative cell division protein compare
PP_2900 +0.6 1.9 conserved protein of unknown function compare
PP_4204 +0.6 2.0 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor compare
PP_1442 +0.6 1.7 conserved protein of unknown function compare
PP_1572 +0.6 3.4 conserved protein of unknown function compare
PP_5587 +0.6 4.3 conserved protein of unknown function compare
PP_1739 +0.6 1.3 conserved membrane protein of unknown function compare
PP_0640 +0.6 2.1 conserved protein of unknown function compare
PP_1054 +0.6 1.3 Type II secretion pathway protein XcpZ compare
PP_4804 +0.6 2.1 RlpA-like lipoprotein compare
PP_2341 +0.6 1.5 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_5428 +0.6 2.1 conserved exported protein of unknown function compare
PP_3346 +0.6 1.8 Nickel transporter ATP-binding protein compare
PP_1576 +0.6 2.1 putative Immunity protein compare
PP_2309 +0.6 0.9 conserved protein of unknown function compare
PP_1268 +0.6 1.9 putative HtrA suppressor protein sohA compare
PP_4896 +0.6 4.2 DNA mismatch repair protein MutL compare
PP_5476 +0.6 2.8 conserved protein of unknown function compare
PP_1544 +0.6 2.3 conserved protein of unknown function compare
PP_t11 +0.6 1.7 tRNA-Lys compare
PP_5229 +0.6 1.9 conserved protein of unknown function compare
PP_1967 +0.6 2.8 tRNA D-aminoacylase compare
PP_1828 +0.6 2.1 conserved protein of unknown function compare
PP_5001 +0.6 1.1 protease HslVU, ATPase component compare
PP_3449 +0.6 1.7 conserved exported protein of unknown function compare
PP_4792 +0.6 1.9 conserved exported protein of unknown function compare
PP_5309 +0.6 0.6 oxidative and nitrosative stress transcriptional dual regulator compare
PP_0182 +0.6 2.3 conserved protein of unknown function compare
PP_1535 +0.6 2.2 putative Methyltransferase compare
PP_1204 +0.6 1.9 putative Lipoprotein compare
PP_3164 +0.6 1.9 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
PP_5483 +0.6 1.5 conserved protein of unknown function compare
PP_2890 +0.6 2.7 exodeoxyribonuclease III / apurinic/apyrimidinic endodeoxyribonuclease VI compare
PP_3002 +0.6 1.8 shikimate dehydrogenase-related enzyme compare
PP_3821 +0.6 3.3 UTP-glucose-1-phosphate uridylyltransferase compare
PP_1038 +0.6 1.6 conserved protein of unknown function compare
PP_5452 +0.6 3.1 protein of unknown function compare
PP_0261 +0.6 2.4 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_0151 +0.6 2.7 conserved exported protein of unknown function compare
PP_1292 +0.6 2.6 Cyclic pyranopterin monophosphate synthase accessory protein compare
PP_0574 +0.6 3.8 DNA-binding response regulator, LuxR family compare
PP_0241 +0.6 1.2 Transporter compare
PP_0758 +0.6 1.8 conserved protein of unknown function compare
PP_1381 +0.6 1.1 4-carboxymuconolactone decarboxylase compare
PP_1690 +0.6 1.8 conserved protein of unknown function compare
PP_2820 +0.6 1.1 HTH-type transcriptional regulator nfxB compare
PP_2794 +0.6 0.8 Oxidoreductase, short chain dehydrogenase/reductase family compare
PP_4136 +0.5 1.1 Transcriptional regulator, LuxR family compare
PP_0246 +0.5 1.7 two-component system DNA-binding response transcriptional dual regulator compare
PP_4944 +0.5 2.1 Carbamoyltransferase compare
PP_5093 +0.5 1.0 twitching motility protein compare
PP_2070 +0.5 1.3 Transcriptional regulator, AraC family compare
PP_5278 +0.5 2.6 4-guanidinobutyraldehyde dehydrogenase compare
PP_4073 +0.5 1.2 conserved exported protein of unknown function compare
PP_1804 +0.5 3.8 Glycosyl transferase WbpL compare
PP_2700 +0.5 1.9 AhpC/TSA family protein compare
PP_5223 +0.5 2.0 regulator of nucleotide diphosphokinase compare
PP_1546 +0.5 2.6 conserved protein of unknown function compare
PP_0198 +0.5 1.9 putative transporter compare
PP_5507 +0.5 1.1 protein of unknown function compare
PP_1598 +0.5 2.0 regulatory intramembrane protein RIP zinc protease compare
PP_1324 +0.5 1.6 putative endonuclease distantly related to archaeal Holliday junction resolvase compare
PP_2411 +0.5 2.0 Major facilitator family transporter compare
PP_0891 +0.5 1.7 conserved exported protein of unknown function compare
PP_1582 +0.5 3.7 conserved protein of unknown function compare
PP_0111 +0.5 2.8 Electron transport protein SCO1/SenC compare
PP_4684 +0.5 2.6 conserved protein of unknown function with kinase-like domain compare
PP_0273 +0.5 2.0 conserved protein of unknown function compare
PP_0610 +0.5 1.3 conserved exported protein of unknown function compare
PP_4287 +0.5 2.2 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase compare
PP_2965 +0.5 2.5 putative tnpA repressor TnpC compare
PP_4502 +0.5 1.8 putative enzyme compare
PP_4786 +0.5 3.0 conserved protein of unknown function compare
PP_2742 +0.5 2.3 conserved protein of unknown function compare
PP_1539 +0.5 3.2 conserved protein of unknown function compare
PP_4880 +0.5 2.8 exoribonuclease R compare
PP_3810 +0.5 1.2 conserved protein of unknown function compare
PP_4785 +0.5 2.5 conserved exported protein of unknown function compare
PP_1245 +0.5 1.8 conserved exported protein of unknown function compare
PP_1185 +0.5 2.1 Outer membrane protein H1 compare
PP_2532 +0.5 1.4 conserved protein of unknown function compare
PP_2882 +0.5 1.5 putative 2-hydroxychromene-2-carboxylate isomerase compare
PP_0195 +0.5 1.4 conserved protein of unknown function compare
PP_0398 +0.5 1.4 Thiosulfate sulfurtransferase GlpE compare
PP_4701 +0.5 0.6 glucose-6-phosphate isomerase compare
PP_4952 +0.5 0.7 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_5702 +0.5 1.3 conserved protein of unknown function compare
PP_1845 +0.5 2.2 Enoyl-CoA hydratase/isomerase family protein compare
PP_1190 +0.5 1.9 conserved protein of unknown function compare
PP_5352 +0.5 3.1 DNA-dependent ATPase I and helicase II, nucleotide Excision Repair Complex compare
PP_4940 +0.5 2.9 Putative glycosyltransferase compare
PP_3643 +0.5 1.8 putative Oxidoreductase compare
PP_2513 +0.5 1.1 4-oxalomesaconate tautomerase compare
PP_4710 +0.5 3.0 tRNA pseudouridine 55 synthase compare
PP_4018 +0.5 1.1 Acetyltransferase, GNAT family compare
PP_1827 +0.5 2.0 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase compare
PP_3295 +0.5 1.4 YeeE/YedE family protein compare
PP_2217 +0.5 1.1 enoyl-CoA hydratase compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Sodium pyruvate in Pseudomonas putida KT2440

For carbon source Sodium pyruvate across organisms