Experiment set10IT016 for Pseudomonas putida KT2440

Compare to:

L-Valine carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1623 +2.4 18.2 RNA polymerase, sigma S (sigma 38) factor compare
PP_1898 +2.2 7.1 MotA/TolQ/ExbB proton channel family protein compare
PP_0642 +2.0 9.0 conserved membrane protein of unknown function compare
PP_4994 +1.8 9.1 conserved protein of unknown function compare
PP_1779 +1.6 7.8 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_0643 +1.5 4.5 protein of unknown function compare
PP_4734 +1.5 9.7 DNA-binding transcriptional dual regulator, LldR-L-lactate compare
PP_1778 +1.4 7.1 Lipopolysaccharide ABC export system, permease protein compare
PP_0007 +1.3 5.7 conserved hypothetical protein compare
PP_1237 +1.2 1.6 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_1074 +1.2 4.5 DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate compare
PP_2144 +1.2 4.7 Transcriptional regulator, TetR family compare
PP_4143 +1.1 4.4 conserved protein of unknown function compare
PP_1912 +1.1 5.2 Phosphate acyltransferase compare
PP_0852 +1.0 5.1 Transcriptional regulator, Cro/CI family compare
PP_0940 +1.0 8.3 putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD compare
PP_0942 +1.0 7.4 regulatory protease compare
PP_4785 +1.0 5.0 conserved exported protein of unknown function compare
PP_4804 +1.0 3.0 RlpA-like lipoprotein compare
PP_4099 +1.0 9.3 two-componenent system BarA/UvrY - regulatory subunit compare
PP_4171 +1.0 8.8 conserved exported protein of unknown function compare
PP_1650 +1.0 9.3 Sensor protein GacS compare
PP_2107 +1.0 2.2 conserved protein of unknown function compare
PP_3880 +0.9 2.3 conserved exported protein of unknown function compare
PP_5452 +0.9 5.3 protein of unknown function compare
PP_5453 +0.9 2.1 conserved protein of unknown function compare
PP_5202 +0.9 2.8 putative cell division protein compare
PP_1562 +0.9 2.7 putative Phage terminase, small subunit compare
PP_4952 +0.9 1.6 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_4050 +0.8 7.3 glycogen synthase compare
PP_5519 +0.8 2.0 conserved protein of unknown function of phage origin compare
PP_1137 +0.8 4.8 high-affinity branched-chain amino acid transporter, ATP binding compare
PP_2737 +0.8 2.0 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_1692 +0.8 3.0 conserved protein of unknown function compare
PP_5654 +0.8 2.4 putative phosphotriesterase compare
PP_2740 +0.8 1.6 Transcriptional regulator, MerR family compare
PP_1224 +0.7 3.7 periplasmic subunit of the TolQRA transport system compare
PP_0547 +0.7 2.6 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_4808 +0.7 1.9 23S rRNA m3psi1915 methyltransferase compare
PP_1214 +0.7 1.7 putative transcriptional regulatory protein compare
PP_0593 +0.7 0.9 putative ribosome-binding factor compare
PP_1293 +0.7 1.1 molybdopterin synthase small subunit compare
PP_1566 +0.7 3.6 Peptidase U35 compare
PP_0959 +0.7 2.4 phospholipid ABC transporter compare
PP_1198 +0.7 1.8 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_4373 +0.7 5.7 Transcriptional regulator FleQ compare
PP_5204 +0.7 2.4 conserved protein of unknown function compare
PP_0191 +0.7 2.8 Transcriptional regulatory protein AlgQ compare
PP_1774 +0.7 1.9 conserved exported protein of unknown function compare
PP_0775 +0.7 2.0 conserved protein of unknown function compare
PP_1584 +0.7 3.7 conserved protein of unknown function compare
PP_4515 +0.7 4.0 Transcriptional regulator, MarR family compare
PP_2016 +0.7 2.9 conserved protein of unknown function compare
PP_0283 +0.7 2.5 Arginine/ornithine transport ATP-binding protein AotP compare
PP_2088 +0.7 3.1 RNA polymerase sigma factor SigX compare
PP_0262 +0.7 2.6 conserved protein of unknown function compare
PP_0872 +0.7 3.7 Peptide chain release factor 3 compare
PP_4184 +0.7 4.6 branched chain amino acid transporter compare
PP_2878 +0.7 1.2 conserved protein of unknown function compare
PP_3899 +0.7 2.2 conserved protein of unknown function, hicB family compare
PP_0058 +0.7 6.3 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
PP_4980 +0.6 2.9 ATP-dependent RNA helicase compare
PP_0986 +0.6 2.5 aminomethyltransferase compare
PP_1917 +0.6 3.6 4-amino-4-deoxychorismate lyase compare
PP_0948 +0.6 1.9 Phosphocarrier protein HPr compare
PP_5053 +0.6 3.4 Protein-export protein SecB compare
PP_2320 +0.6 4.6 conserved exported protein of unknown function compare
PP_2389 +0.6 3.9 conserved protein of unknown function compare
PP_3821 +0.6 4.2 UTP-glucose-1-phosphate uridylyltransferase compare
PP_2083 +0.6 2.3 putative Lipase compare
PP_5705 +0.6 1.2 protein of unknown function compare
PP_2472 +0.6 2.4 putative transcriptional regulator, MerR family compare
PP_1814 +0.6 2.6 conserved protein of unknown function compare
PP_3398 +0.6 1.4 putative Curli fiber surface-exposed nucleator CsgB compare
PP_3098 +0.6 1.0 conserved protein of unknown function compare
PP_1310 +0.6 1.7 conserved hypothetical protein compare
PP_4597 +0.6 1.8 Cyclic pyranopterin monophosphate synthase compare
PP_1827 +0.6 2.8 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase compare
PP_3541 +0.6 1.4 Transporter, MgtC family compare
PP_1307 +0.6 3.4 AsnC family transcriptional regulator compare
PP_2457 +0.6 3.0 DNA-binding transcriptional repressor compare
PP_1567 +0.6 4.0 Capsid protein compare
PP_2580 +0.6 2.8 conserved protein of unknown function compare
PP_5247 +0.6 2.3 conserved protein of unknown function compare
PP_4792 +0.6 1.0 conserved exported protein of unknown function compare
PP_4776 +0.6 3.6 AsnC family transcriptional regulator compare
PP_5253 +0.6 1.7 Arylesterase compare
PP_0958 +0.6 2.8 phospholipid ABC transporter ATP-binding subunit compare
PP_3824 +0.6 1.8 conserved exported protein of unknown function compare
PP_1543 +0.6 3.2 conserved protein of unknown function compare
PP_4173 +0.6 3.7 Sensor histidine kinase/response regulator compare
PP_1777 +0.6 4.2 phosphomannomutase compare
PP_5176 +0.5 2.7 conserved protein of unknown function compare
PP_5017 +0.5 0.8 Sec-independent protein translocase protein TatB compare
PP_4211 +0.5 2.9 outer membrane pyoverdine efflux protein compare
PP_2319 +0.5 3.1 conserved protein of unknown function compare
PP_1575 +0.5 1.9 conserved protein of unknown function compare
PP_0151 +0.5 1.7 conserved exported protein of unknown function compare
PP_4178 +0.5 1.7 Dienelactone hydrolase family protein compare
PP_1140 +0.5 4.1 branched chain amino acid transporter - permease subunit compare
PP_4842 +0.5 3.6 putative Urea ABC transporter compare
PP_2773 +0.5 1.5 conserved protein of unknown function compare
PP_2388 +0.5 1.9 Transporter, LysE family compare
PP_4936 +0.5 2.7 O-antigen polymerase compare
PP_5160 +0.5 3.1 conserved exported protein of unknown function compare
PP_1780 +0.5 4.7 putative mannosyltransferase compare
PP_0856 +0.5 1.6 conserved lipoprotein of unknown function compare
PP_1048 +0.5 1.1 putative protein secretion protein for export compare
PP_4926 +0.5 2.7 HlyD family secretion protein compare
PP_4159 +0.5 2.0 Potassium-transporting ATPase C chain compare
PP_0540 +0.5 2.9 conserved inner membrane protein compare
PP_0929 +0.5 2.9 putative Lipoprotein compare
PP_1138 +0.5 1.8 branched chain amino acid transporter - ATP binding subunit compare
PP_3579 +0.5 2.5 conserved membrane protein of unknown function compare
PP_4797 +0.5 1.1 conserved protein of unknown function compare
PP_2254 +0.5 2.5 Transcriptional regulator, GntR family compare
PP_1390 +0.5 1.3 conserved exported protein of unknown function compare
PP_0022 +0.5 0.8 hypothetical protein compare
PP_1309 +0.5 2.8 conserved exported protein of unknown function compare
PP_2785 +0.5 2.1 conserved exported protein of unknown function compare
PP_1568 +0.5 0.9 conserved protein of unknown function compare
PP_2082 +0.5 3.6 phosphoenolpyruvate synthetase compare
PP_0941 +0.5 1.7 putative ribosome associated protein compare
PP_2390 +0.5 3.0 Transcriptional regulator, LysR family compare
PP_1139 +0.5 3.9 branched chain amino acid transporter - permease subunit compare
PP_2245 +0.5 3.6 Transcriptional regulator, Cro/CI family compare
PP_2747 +0.5 0.4 conserved protein of unknown function compare
PP_0168 +0.5 4.3 putative surface adhesion protein compare
PP_0960 +0.5 2.2 phospholipid ABC transporter binding protein compare
PP_1845 +0.5 2.2 Enoyl-CoA hydratase/isomerase family protein compare
PP_3003 +0.5 1.6 3-dehydroquinate dehydratase 3, type II compare
PP_0938 +0.5 3.0 conserved protein of unknown function compare
PP_1215 +0.5 0.7 Crossover junction endodeoxyribonuclease RuvC compare
PP_4682 +0.5 1.7 conserved protein of unknown function containing tetratricopeptide repeat domain compare
PP_1522 +0.5 1.7 major cold shock protein compare
PP_2060 +0.5 1.2 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_4837 +0.5 1.9 conserved protein of unknown function compare
PP_1322 +0.5 0.7 putative Lipoprotein compare
PP_2695 +0.5 1.5 Transcriptional regulator, LysR family compare
PP_3732 +0.5 2.9 Enoyl-CoA hydratase/isomerase family protein compare
PP_3064 +0.5 1.5 Phage tail protein compare
PP_2197 +0.5 1.5 conserved exported protein of unknown function compare
PP_0893 +0.5 1.8 ThiJ/PfpI family protein compare
PP_3164 +0.4 1.4 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
PP_0574 +0.4 3.5 DNA-binding response regulator, LuxR family compare
PP_4866 +0.4 3.3 High-affinity branched-chain amino acid transport system permease protein BraD compare
PP_3434 +0.4 1.1 conserved protein of unknown function compare
PP_4660 +0.4 1.8 Transcriptional regulator, LysR family compare
PP_1515 +0.4 1.7 Transcriptional regulator, tetR family compare
PP_0694 +0.4 1.7 conserved protein of unknown function compare
PP_4523 +0.4 2.4 putative Agmatinase compare
PP_4943 +0.4 1.2 putative Glycosyl transferase compare
PP_5200 +0.4 3.3 proline aminopeptidase P II compare
PP_2256 +0.4 2.1 Transcriptional regulator, Cro/CI family compare
PP_2189 +0.4 2.2 conserved protein of unknown function compare
PP_2309 +0.4 0.8 conserved protein of unknown function compare
PP_1141 +0.4 2.8 branched-chain amino acids ABC transporter - periplasmic leucine binding subunit compare
PP_0254 +0.4 2.0 conserved protein of unknown function compare
PP_4619 +0.4 2.4 Maleylacetoacetate isomerase compare
PP_5500 +0.4 1.9 protein of unknown function compare
PP_5445 +0.4 1.2 conserved protein of unknown function compare
PP_5594 +0.4 1.3 conserved protein of unknown function compare
PP_2360 +0.4 1.5 putative type 1 pili subunit CsuA/B protein compare
PP_5152 +0.4 2.2 conserved exported protein of unknown function compare
PP_2247 +0.4 1.7 putative Endoribonuclease compare
PP_2700 +0.4 0.9 AhpC/TSA family protein compare
PP_4172 +0.4 2.2 conserved exported protein of unknown function compare
PP_5480 +0.4 2.0 conserved exported protein of unknown function compare
PP_4356 +0.4 1.4 Flagellar protein FliO compare
PP_3906 +0.4 1.0 conserved protein of unknown function compare
PP_4814 +0.4 1.8 ATP-dependent protease La domain protein compare
PP_2793 +0.4 1.0 Acyl-CoA dehydrogenase family protein compare
PP_1998 +0.4 2.7 putative cell division protein compare
PP_2291 +0.4 1.7 conserved protein of unknown function compare
PP_5675 +0.4 1.6 conserved protein of unknown function compare
PP_1028 +0.4 1.6 Transcriptional regulator, LysR family compare
PP_1583 +0.4 1.5 putative Structural protein P5 compare
PP_4593 +0.4 1.2 conserved protein of unknown function compare
PP_2647 +0.4 2.7 Major facilitator family transporter compare
PP_2933 +0.4 2.2 GSH-dependent disulfide bond oxidoreductase compare
PP_5076 +0.4 3.7 L-glutamate synthase(NADPH) alpha subunit compare
PP_1535 +0.4 1.4 putative Methyltransferase compare
PP_3724 +0.4 2.6 putative Acyl-CoA synthetase compare
PP_1801 +0.4 3.2 Glycosyl transferase WbpY compare
PP_1573 +0.4 2.3 putative Major tail protein compare
PP_5609 +0.4 1.8 conserved protein of unknown function compare
PP_1384 +0.4 2.7 Probable efflux pump outer membrane protein TtgC compare
PP_2341 +0.4 0.9 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_4212 +0.4 1.7 pyoverdine biosynthesis related protein compare
PP_3121 +0.4 2.0 transcriptional regulator, LysR family compare
PP_5299 +0.4 2.4 glutamate-putrescine ligase compare
PP_1556 +0.4 2.2 conserved protein of unknown function compare
PP_3738 +0.4 1.7 putative Transcriptional regulator VanR compare
PP_4944 +0.4 1.4 Carbamoyltransferase compare
PP_3408 +0.4 1.5 cobalt transporter subunit A compare
PP_1548 +0.4 0.8 conserved protein of unknown function compare
PP_4051 +0.4 2.6 malto-oligosyltrehalose trehalohydrolase compare
PP_1199 +0.4 2.2 toxin-antitoxin system, higB toxin like compare
PP_5183 +0.4 2.4 glutamylpolyamine synthetase compare
PP_5704 +0.4 1.1 conserved protein of unknown function compare


Specific Phenotypes

For 18 genes in this experiment

For carbon source L-Valine in Pseudomonas putida KT2440

For carbon source L-Valine across organisms