Experiment set10IT014 for Pseudomonas putida KT2440

Compare to:

L-Proline carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1623 +2.6 17.2 RNA polymerase, sigma S (sigma 38) factor compare
PP_0547 +2.4 9.9 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_4122 +1.9 3.4 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_0406 +1.9 13.2 Nucleotidyltransferase family protein compare
PP_4099 +1.6 15.7 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1468 +1.5 6.0 Tyrosine recombinase XerD compare
PP_5230 +1.5 5.0 Tyrosine recombinase XerC compare
PP_0138 +1.5 8.7 conserved membrane protein of unknown function compare
PP_1650 +1.4 13.7 Sensor protein GacS compare
PP_1779 +1.4 4.8 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_3902 +1.4 2.1 conserved protein of unknown function compare
PP_1575 +1.2 4.0 conserved protein of unknown function compare
PP_4874 +1.2 1.2 50S ribosomal protein L9 compare
PP_3883 +1.2 2.7 putative Phage holin compare
PP_0261 +1.2 6.3 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_1216 +1.1 1.9 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_1568 +1.1 1.8 conserved protein of unknown function compare
PP_0673 +1.1 2.3 conserved protein of unknown function compare
PP_1583 +1.1 4.2 putative Structural protein P5 compare
PP_0848 +1.0 1.8 donor of Fe2+ and regulator of cysteine desulfurase activity compare
PP_1560 +1.0 4.2 conserved protein of unknown function compare
PP_0401 +1.0 1.6 Ribosomal RNA small subunit methyltransferase A compare
PP_5267 +1.0 2.4 putative cytochrome c5 compare
PP_1566 +1.0 5.2 Peptidase U35 compare
PP_5007 +1.0 1.3 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_4273 +1.0 1.9 Transcriptional regulator, MerR family compare
PP_5453 +1.0 1.7 conserved protein of unknown function compare
PP_3876 +0.9 2.5 conserved protein of unknown function compare
PP_4938 +0.9 5.2 putative Glycosyl transferase compare
PP_4528 +0.9 1.9 conserved protein of unknown function compare
PP_1548 +0.9 2.5 conserved protein of unknown function compare
PP_0425 +0.9 3.3 conserved protein of unknown function compare
PP_2144 +0.9 2.8 Transcriptional regulator, TetR family compare
PP_1567 +0.9 5.2 Capsid protein compare
PP_3637 +0.9 1.5 putative Sulfonate ABC transporter, ATP-binding protein compare
PP_3904 +0.9 3.3 conserved protein of unknown function compare
PP_0846 +0.9 1.6 DnaK-like molecular chaperone specific for IscU compare
PP_2387 +0.9 2.6 conserved protein of unknown function compare
PP_3892 +0.9 1.3 conserved protein of unknown function compare
PP_1563 +0.9 6.1 putative Phage terminase, large subunit compare
PP_1198 +0.9 2.1 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_1224 +0.9 4.9 periplasmic subunit of the TolQRA transport system compare
PP_0785 +0.9 3.8 putative cysZ protein, required for sulfate transport compare
PP_3043 +0.9 2.7 conserved protein of unknown function compare
PP_1580 +0.8 5.4 conserved protein of unknown function compare
PP_1571 +0.8 2.4 conserved protein of unknown function compare
PP_1577 +0.8 6.9 Phage tail tape meausure protein, lambda family compare
PP_1574 +0.8 3.8 conserved protein of unknown function compare
PP_1215 +0.8 1.5 Crossover junction endodeoxyribonuclease RuvC compare
PP_0048 +0.8 1.3 conserved protein of unknown function compare
PP_1570 +0.8 2.5 Head-tail adaptor compare
PP_2083 +0.8 2.1 putative Lipase compare
PP_4936 +0.8 3.5 O-antigen polymerase compare
PP_3916 +0.8 2.1 conserved protein of unknown function compare
PP_5110 +0.8 2.1 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_1713 +0.8 0.8 Transcriptional regulator PcaQ compare
PP_4943 +0.8 1.2 putative Glycosyl transferase compare
PP_4268 +0.8 1.2 nucleoid-associated broad specificity regulator compare
PP_0257 +0.8 2.5 protein sulfur transferase compare
PP_4464 +0.8 2.4 Transcriptional regulator, LysR family compare
PP_2633 +0.8 1.5 conserved protein of unknown function compare
PP_0150 +0.8 2.5 conserved exported protein of unknown function compare
PP_4058 +0.8 5.0 1,4-alpha-glucan branching enzyme compare
PP_3874 +0.8 2.0 conserved protein of unknown function compare
PP_2403 +0.7 0.7 Chemotaxis protein CheY compare
PP_2622 +0.7 1.5 conserved protein of unknown function compare
PP_4952 +0.7 1.2 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_2899 +0.7 0.7 conserved exported protein of unknown function compare
PP_1579 +0.7 6.0 conserved protein of unknown function compare
PP_4171 +0.7 6.6 conserved exported protein of unknown function compare
PP_0283 +0.7 2.5 Arginine/ornithine transport ATP-binding protein AotP compare
PP_4254 +0.7 1.2 conserved protein of unknown function compare
PP_3035 +0.7 1.7 conserved protein of unknown function compare
PP_0856 +0.7 1.8 conserved lipoprotein of unknown function compare
PP_1544 +0.7 2.3 conserved protein of unknown function compare
PP_5471 +0.7 0.7 putative response regulator receiver protein compare
PP_4098 +0.7 1.2 UvrABC system protein C compare
PP_3824 +0.7 2.2 conserved exported protein of unknown function compare
PP_5500 +0.7 2.7 protein of unknown function compare
PP_1513 +0.7 1.9 Ribosomal RNA small subunit methyltransferase J compare
PP_1565 +0.7 4.5 Phage portal protein, HK97 family compare
PP_5582 +0.7 1.0 conserved protein of unknown function compare
PP_5648 +0.7 2.0 conserved exported protein of unknown function compare
PP_0235 +0.7 2.1 Peroxidase compare
PP_0593 +0.7 0.7 putative ribosome-binding factor compare
PP_4471 +0.7 2.0 Magnesium transporter compare
PP_1581 +0.7 5.1 BNR domain protein compare
PP_0973 +0.7 2.6 Nucleoid-associated protein PP_0973 compare
PP_1562 +0.7 1.1 putative Phage terminase, small subunit compare
PP_1573 +0.7 3.5 putative Major tail protein compare
PP_0065 +0.7 1.8 NAD-binding component of TrK potassium transporter compare
PP_2090 +0.7 3.0 Uroporphyrinogen-III C-methyltransferase compare
PP_2889 +0.7 2.4 putative Transmembrane regulator PrtR compare
PP_3647 +0.7 2.5 putative Oxidoreductase compare
PP_4793 +0.7 1.6 conserved protein of unknown function compare
PP_4859 +0.7 3.2 Transcriptional regulator, TetR family compare
PP_5476 +0.7 3.0 conserved protein of unknown function compare
PP_2433 +0.7 1.1 conserved protein of unknown function compare
PP_1293 +0.7 0.5 molybdopterin synthase small subunit compare
PP_1582 +0.7 4.9 conserved protein of unknown function compare
PP_5255 +0.7 3.0 putative hydrolase compare
PP_1543 +0.7 2.8 conserved protein of unknown function compare
PP_1122 +0.6 0.9 OmpA family protein compare
PP_4356 +0.6 1.0 Flagellar protein FliO compare
PP_2777 +0.6 2.1 putative Acyl carrier protein compare
PP_4662 +0.6 2.7 conserved protein of unknown function compare
PP_4172 +0.6 3.0 conserved exported protein of unknown function compare
PP_1439 +0.6 1.8 conserved exported protein of unknown function compare
PP_3487 +0.6 1.4 conserved exported protein of unknown function compare
PP_3241 +0.6 1.0 conserved exported protein of unknown function compare
PP_1113 +0.6 4.2 Pyridoxal-phosphate dependent enzyme family protein compare
PP_2595 +0.6 2.8 putative ABC transporter, permease/ATP-binding protein compare
PP_4804 +0.6 2.0 RlpA-like lipoprotein compare
PP_1783 +0.6 1.1 dTDP-glucose pyrophosphorylase compare
PP_2840 +0.6 2.1 putative Membrane protein compare
PP_0711 +0.6 1.5 putative hydrolase compare
PP_3880 +0.6 1.1 conserved exported protein of unknown function compare
PP_2816 +0.6 1.5 putative Transcriptional regulator NfxB compare
PP_2147 +0.6 2.0 conserved exported protein of unknown function compare
PP_2640 +0.6 2.1 Acetyltransferase, GNAT family compare
PP_1709 +0.6 2.4 Fumarylacetoacetate hydrolase family protein compare
PP_3911 +0.6 2.6 conserved protein of unknown function compare
PP_2510 +0.6 1.3 conserved protein of unknown function compare
PP_1733 +0.6 1.4 membrane ATPase of the MinC-MinD-MinE system compare
PP_0307 +0.6 1.5 conserved exported protein of unknown function compare
PP_1564 +0.6 2.2 conserved exported protein of unknown function compare
PP_2740 +0.6 1.0 Transcriptional regulator, MerR family compare
PP_0513 +0.6 0.7 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP compare
PP_1630 +0.6 2.5 Regulatory protein RecX compare
PP_5114 +0.6 1.0 putative adenine methyltransferase compare
PP_0287 +0.6 2.4 conserved exported protein of unknown function compare
PP_2253 +0.6 1.2 Transcriptional regulator, GntR family compare
PP_4545 +0.6 2.2 beta-ketodecanoyl-(Acyl-carrier-protein) synthase compare
PP_3164 +0.6 1.7 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
PP_3580 +0.6 0.7 conserved protein of unknown function compare
PP_3591 +0.6 2.0 Delta 1-piperideine-2-carboxylate reductase compare
PP_3821 +0.6 3.3 UTP-glucose-1-phosphate uridylyltransferase compare
PP_0273 +0.6 0.9 conserved protein of unknown function compare
PP_3766 +0.6 1.3 Lactoylglutathione lyase compare
PP_0260 +0.6 2.8 ADP-sugar pyrophosphorylase compare
PP_1981 +0.6 2.1 tRNA-dihydrouridine synthase C compare
PP_4506 +0.6 1.9 Nitroreductase family protein compare
PP_1572 +0.6 3.0 conserved protein of unknown function compare
PP_2520 +0.5 1.2 conserved protein of unknown function compare
PP_4785 +0.5 2.5 conserved exported protein of unknown function compare
PP_1578 +0.5 1.7 conserved protein of unknown function compare
PP_2320 +0.5 4.0 conserved exported protein of unknown function compare
PP_5489 +0.5 1.6 conserved protein of unknown function compare
PP_4855 +0.5 2.5 Osmotically-inducible lipoprotein OsmE compare
PP_4198 +0.5 2.5 OmpA family protein compare
PP_4940 +0.5 2.6 Putative glycosyltransferase compare
PP_0957 +0.5 1.0 D-arabinose 5-phosphate isomerase compare
PP_5508 +0.5 0.8 conserved protein of unknown function compare
PP_5053 +0.5 2.1 Protein-export protein SecB compare
PP_5294 +0.5 2.4 Ribonuclease PH compare
PP_5633 +0.5 1.6 conserved protein of unknown function compare
PP_3064 +0.5 1.6 Phage tail protein compare
PP_2307 +0.5 0.8 conserved protein of unknown function compare
PP_1217 +0.5 1.4 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_1731 +0.5 1.5 23S rRNA (746) and tRNA (32) pseudouridine synthase compare
PP_4997 +0.5 0.6 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_3808 +0.5 1.3 Antibiotic synthesis protein MbtH compare
PP_1055 +0.5 0.9 Type II secretion pathway protein GspN compare
PP_3525 +0.5 2.4 conserved exported protein of unknown function compare
PP_2500 +0.5 2.0 conserved protein of unknown function compare
PP_1706 +0.5 1.7 Nitrite reductase compare
PP_3380 +0.5 1.7 2-ketogluconate utilization repressor compare
PP_4691 +0.5 1.6 sugar fermentation stimulation protein A compare
PP_4317 +0.5 0.6 conserved protein of unknown function compare
PP_5221 +0.5 1.5 conserved protein of unknown function, UPF0178 family compare
PP_5640 +0.5 1.1 conserved protein of unknown function compare
PP_2411 +0.5 2.6 Major facilitator family transporter compare
PP_4792 +0.5 1.4 conserved exported protein of unknown function compare
PP_0301 +0.5 1.8 betainyl-CoA thiolase compare
PP_2509 +0.5 1.5 conserved protein of unknown function compare
PP_4930 +0.5 1.5 putative small multidrug resistance protein compare
PP_2814 +0.5 2.1 conserved protein of unknown function compare
PP_0679 +0.5 2.2 conserved exported protein of unknown function compare
PP_2306 +0.5 1.0 conserved exported protein of unknown function compare
PP_0384 +0.5 2.0 Transcriptional regulator, AsnC family compare
PP_3908 +0.5 1.6 conserved protein of unknown function compare
PP_0972 +0.5 1.2 UPF0213 protein PP_0972 compare
PP_1168 +0.5 2.5 D-glucuronate / D-galacturonate TRAP transporter, small permease component (from data) compare
PP_5666 +0.5 1.8 putative microcin B17-like processing protein, McbB family compare
PP_5473 +0.5 1.2 putative transcriptional regulator, LuxR family compare
PP_5240 +0.5 1.2 Response regulator compare
PP_5266 +0.5 2.8 putative acetyl-CoA hydrolase family protein compare
PP_1099 +0.5 0.6 Cold shock protein CapB compare
PP_4994 +0.5 1.5 conserved protein of unknown function compare
PP_0989 +0.5 1.6 glycine cleavage system H protein 1 compare
PP_3746 +0.5 1.9 glycolate oxidase, putative FAD-binding subunit compare
PP_3738 +0.5 1.5 putative Transcriptional regulator VanR compare
PP_1561 +0.5 2.7 putative Phage holin compare
PP_3427 +0.4 1.4 Multidrug efflux RND outer membrane protein OprN compare
PP_4173 +0.4 2.5 Sensor histidine kinase/response regulator compare
PP_1776 +0.4 3.7 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_5714 +0.4 1.6 conserved protein of unknown function compare
PP_1545 +0.4 2.2 conserved protein of unknown function compare
PP_4567 +0.4 2.5 conserved protein of unknown function compare
PP_0236 +0.4 1.3 NAD(P)H-dependent FMN reductase subunit compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source L-Proline in Pseudomonas putida KT2440

For carbon source L-Proline across organisms