Experiment set10IT013 for Pseudomonas putida KT2440

Compare to:

L-Lysine carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1623 +4.3 28.9 RNA polymerase, sigma S (sigma 38) factor compare
PP_4099 +4.0 38.2 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1650 +3.9 32.1 Sensor protein GacS compare
PP_4480 +3.0 23.7 arginine N-succinyltransferase, subunit alpha compare
PP_3731 +2.2 14.5 Transcriptional regulator, TetR family compare
PP_5212 +1.9 10.3 Oxidoreductase, iron-sulfur-binding compare
PP_2144 +1.8 4.6 Transcriptional regulator, TetR family compare
PP_3098 +1.8 2.5 conserved protein of unknown function compare
PP_0593 +1.7 1.8 putative ribosome-binding factor compare
PP_4171 +1.7 12.0 conserved exported protein of unknown function compare
PP_1575 +1.6 3.2 conserved protein of unknown function compare
PP_1216 +1.5 3.8 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_5571 +1.5 2.2 conserved protein of unknown function compare
PP_4994 +1.4 6.1 conserved protein of unknown function compare
PP_4481 +1.4 5.1 Succinylornithine transaminase/acetylornithine aminotransferase compare
PP_1237 +1.4 2.3 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_3732 +1.3 3.5 Enoyl-CoA hydratase/isomerase family protein compare
PP_5652 +1.3 2.1 conserved protein of unknown function, phage origin compare
PP_4273 +1.3 1.4 Transcriptional regulator, MerR family compare
PP_2101 +1.3 3.0 DNA-binding response regulator in two-component regulatory system with EvgS compare
PP_0516 +1.3 3.8 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II compare
PP_1113 +1.2 8.4 Pyridoxal-phosphate dependent enzyme family protein compare
PP_1562 +1.2 1.8 putative Phage terminase, small subunit compare
PP_1778 +1.2 4.4 Lipopolysaccharide ABC export system, permease protein compare
PP_1198 +1.2 2.3 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_1898 +1.2 4.6 MotA/TolQ/ExbB proton channel family protein compare
PP_4785 +1.2 4.7 conserved exported protein of unknown function compare
PP_5053 +1.2 4.8 Protein-export protein SecB compare
PP_1779 +1.2 4.6 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_0191 +1.2 2.9 Transcriptional regulatory protein AlgQ compare
PP_1568 +1.2 1.7 conserved protein of unknown function compare
PP_0540 +1.1 5.8 conserved inner membrane protein compare
PP_4173 +1.1 7.0 Sensor histidine kinase/response regulator compare
PP_1548 +1.1 2.7 conserved protein of unknown function compare
PP_5502 +1.1 2.2 ribosome modulation factor compare
PP_5058 +1.1 5.0 Carboxy-terminal-processing protease compare
PP_5714 +1.1 2.7 conserved protein of unknown function compare
PP_4271 +1.1 1.3 conserved protein of unknown function compare
PP_1574 +1.1 4.3 conserved protein of unknown function compare
PP_4373 +1.1 6.9 Transcriptional regulator FleQ compare
PP_4477 +1.1 4.7 N-succinylarginine dihydrolase compare
PP_2720 +1.0 1.2 conserved protein of unknown function compare
PP_1041 +1.0 1.9 twin arginine protein export complex subunit compare
PP_1268 +1.0 2.3 putative HtrA suppressor protein sohA compare
PP_5644 +1.0 1.8 conserved membrane protein of unknown function compare
PP_4910 +1.0 1.4 conserved protein of unknown function compare
PP_4478 +1.0 5.5 N-succinylglutamate 5-semialdehyde dehydrogenase compare
PP_0282 +1.0 5.0 L-arginine ABC transporter - periplasmic binding subunit compare
PP_5253 +1.0 1.8 Arylesterase compare
PP_2499 +1.0 1.0 conserved protein of unknown function compare
PP_2899 +0.9 1.0 conserved exported protein of unknown function compare
PP_1584 +0.9 3.6 conserved protein of unknown function compare
PP_4697 +0.9 1.8 poly(A) polymerase compare
PP_1058 +0.9 7.3 conserved protein of unknown function compare
PP_1845 +0.9 2.4 Enoyl-CoA hydratase/isomerase family protein compare
PP_1451 +0.9 2.6 conserved exported protein of unknown function compare
PP_1583 +0.9 2.4 putative Structural protein P5 compare
PP_2677 +0.9 2.1 conserved exported protein of unknown function compare
PP_1415 +0.9 2.0 putative membrane associated enzyme subunit compare
PP_3899 +0.9 1.2 conserved protein of unknown function, hicB family compare
PP_1702 +0.9 2.5 Recombination-associated protein RdgC compare
PP_5110 +0.9 1.7 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_4808 +0.9 1.5 23S rRNA m3psi1915 methyltransferase compare
PP_4629 +0.9 2.4 Sensory box protein compare
PP_1563 +0.8 5.3 putative Phage terminase, large subunit compare
PP_1442 +0.8 2.7 conserved protein of unknown function compare
PP_0283 +0.8 2.2 Arginine/ornithine transport ATP-binding protein AotP compare
PP_2864 +0.8 1.4 conserved protein of unknown function compare
PP_5491 +0.8 1.4 conserved protein of unknown function with SEC-C motif domain compare
PP_1570 +0.8 1.8 Head-tail adaptor compare
PP_1581 +0.8 5.7 BNR domain protein compare
PP_2816 +0.8 2.4 putative Transcriptional regulator NfxB compare
PP_1655 +0.8 3.6 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_3522 +0.8 1.8 conserved protein of unknown function compare
PP_1099 +0.8 1.8 Cold shock protein CapB compare
PP_4479 +0.8 2.7 arginine N-succinyltransferase, subunit beta compare
PP_1572 +0.8 4.1 conserved protein of unknown function compare
PP_3916 +0.8 1.7 conserved protein of unknown function compare
PP_2882 +0.8 3.1 putative 2-hydroxychromene-2-carboxylate isomerase compare
PP_5688 +0.8 3.3 putative NAD(FAD)-dependent dehydrogenase with Fer2_4 domain compare
PP_0886 +0.8 1.3 conserved exported protein of unknown function compare
PP_2847 +0.8 1.5 Urease accessory protein UreJ compare
PP_2976 +0.8 1.5 putative transposase compare
PP_0725 +0.8 3.4 conserved hypothetical TPR repeat protein compare
PP_4902 +0.8 1.3 Oligoribonuclease compare
PP_3014 +0.8 1.3 conserved exported protein of unknown function compare
PP_1577 +0.8 5.5 Phage tail tape meausure protein, lambda family compare
PP_3460 +0.8 1.1 quinohemoprotein amine dehydrogenase, gamma subunit compare
PP_1204 +0.8 3.3 putative Lipoprotein compare
PP_5144 +0.7 3.4 conserved protein of unknown function compare
PP_1579 +0.7 6.1 conserved protein of unknown function compare
PP_5230 +0.7 1.7 Tyrosine recombinase XerC compare
PP_1582 +0.7 5.2 conserved protein of unknown function compare
PP_0957 +0.7 1.1 D-arabinose 5-phosphate isomerase compare
PP_3904 +0.7 2.5 conserved protein of unknown function compare
PP_0697 +0.7 3.2 ribosomal-protein-S18-alanine N-acetyltransferase compare
PP_0281 +0.7 3.4 Amino acid ABC transporter, permease protein compare
PP_5027 +0.7 1.2 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_0713 +0.7 3.4 Kef-type potassium/proton antiporter, CPA2 family compare
PP_3562 +0.7 3.6 conserved exported protein of unknown function compare
PP_4681 +0.7 1.5 conserved protein of unknown function compare
PP_4947 +0.7 5.7 proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase compare
PP_5430 +0.7 1.9 protein of unknown function compare
PP_1566 +0.7 2.3 Peptidase U35 compare
PP_4209 +0.7 3.0 ABC export system, membrane fusion protein compare
PP_2844 +0.7 1.7 Urease subunit beta compare
PP_0257 +0.7 2.2 protein sulfur transferase compare
PP_3551 +0.7 1.2 DNA-binding response regulator, LuxR family compare
PP_1580 +0.7 4.1 conserved protein of unknown function compare
PP_1447 +0.7 1.9 conserved protein of unknown function compare
PP_1116 +0.7 2.8 Site-specific recombinase, resolvase family compare
PP_2750 +0.7 1.9 putative Branched-chain amino acid ABC transporter, permease protein compare
PP_3892 +0.7 0.9 conserved protein of unknown function compare
PP_3824 +0.7 1.8 conserved exported protein of unknown function compare
PP_4100 +0.7 2.8 Transcriptional regulator, Cro/CI family compare
PP_4953 +0.7 2.8 putative oxidoreductase with FAD/NAD(P)-binding domain compare
PP_4004 +0.7 1.5 DNA translocase FtsK compare
PP_0035 +0.7 1.1 putative bactoprenol-linked glycose transferase compare
PP_0168 +0.7 5.6 putative surface adhesion protein compare
PP_3902 +0.7 0.9 conserved protein of unknown function compare
PP_1217 +0.7 1.4 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_5241 +0.7 1.5 DNA-binding response regulator, LuxR family compare
PP_0274 +0.7 1.0 putative transcriptional regulator containing HTH domain compare
PP_3434 +0.7 0.9 conserved protein of unknown function compare
PP_1576 +0.7 1.9 putative Immunity protein compare
PP_5429 +0.7 1.8 protein of unknown function compare
PP_1413 +0.7 2.8 Uracil-DNA glycosylase compare
PP_0856 +0.6 1.7 conserved lipoprotein of unknown function compare
PP_2000 +0.6 1.1 amidophosphoribosyl transferase compare
PP_0361 +0.6 1.9 putative Competence protein ComF compare
PP_2459 +0.6 1.6 ribose pyranase compare
PP_1573 +0.6 3.4 putative Major tail protein compare
PP_5558 +0.6 2.1 putative transcriptional xre family of phage origin compare
PP_1210 +0.6 2.7 DNA-binding stress protein compare
PP_2083 +0.6 1.6 putative Lipase compare
PP_0151 +0.6 2.0 conserved exported protein of unknown function compare
PP_3447 +0.6 0.9 conserved membrane protein of unknown function compare
PP_4069 +0.6 1.7 conserved protein of unknown function compare
PP_5519 +0.6 1.7 conserved protein of unknown function of phage origin compare
PP_1112 +0.6 2.8 conserved membrane protein of unknown function compare
PP_4247 +0.6 1.0 Exonuclease compare
PP_2840 +0.6 1.9 putative Membrane protein compare
PP_3424 +0.6 2.6 Type II secretion pathway protein XcpS compare
PP_3823 +0.6 2.1 Cytochrome c-type protein compare
PP_0192 +0.6 2.6 putative FKBP-type 25 kDa peptidyl-prolyl cis-trans isomerase compare
PP_4172 +0.6 2.1 conserved exported protein of unknown function compare
PP_0335 +0.6 2.5 Glutathione S-transferase family protein compare
PP_2972 +0.6 1.6 conserved protein of unknown function compare
PP_0562 +0.6 2.7 Methyl-accepting chemotaxis protein CtpL compare
PP_2503 +0.6 1.3 putative 3-oxoacyl-(Acyl-carrier-protein) reductase compare
PP_2858 +0.6 1.0 conserved exported protein of unknown function compare
PP_4952 +0.6 0.7 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_3871 +0.6 1.5 conserved protein of unknown function compare
PP_5247 +0.6 1.4 conserved protein of unknown function compare
PP_5066 +0.6 1.9 K(+)/H(+) antiporter NhaP2 compare
PP_0280 +0.6 3.0 Amino acid ABC transporter, permease protein compare
PP_1544 +0.6 2.2 conserved protein of unknown function compare
PP_3519 +0.6 0.8 putative Lipoprotein compare
PP_3908 +0.6 1.1 conserved protein of unknown function compare
PP_4464 +0.6 1.6 Transcriptional regulator, LysR family compare
PP_2446 +0.6 1.5 conserved exported protein of unknown function compare
PP_1808 +0.6 1.8 glucose-6-phosphate isomerase compare
PP_5051 +0.6 0.7 conserved protein of unknown function compare
PP_3866 +0.6 2.0 conserved protein of unknown function compare
PP_0784 +0.6 1.6 conserved protein of unknown function compare
PP_3000 +0.6 1.6 MaoC domain protein compare
PP_0145 +0.6 2.1 Na+/Pi-cotransporter compare
PP_t57 +0.6 1.5 tRNA-Arg compare
PP_4926 +0.6 2.3 HlyD family secretion protein compare
PP_2121 +0.6 1.5 putative Lipoprotein compare
PP_3164 +0.6 1.6 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
PP_0684 +0.6 2.3 FKBP-type peptidyl-prolyl cis-trans isomerase compare
PP_1578 +0.6 2.6 conserved protein of unknown function compare
PP_3142 +0.6 2.4 putative Sugar transferase compare
PP_1454 +0.6 1.2 conserved protein of unknown function compare
PP_1131 +0.6 1.5 outer membrane lipoprotein compare
PP_1027 +0.6 2.2 Exodeoxyribonuclease 7 large subunit compare
PP_1245 +0.6 2.4 conserved exported protein of unknown function compare
PP_2525 +0.6 2.6 conserved protein of unknown function compare
PP_1719 +0.6 3.7 Tail-specific protease prc compare
PP_0138 +0.6 2.7 conserved membrane protein of unknown function compare
PP_2090 +0.6 1.3 Uroporphyrinogen-III C-methyltransferase compare
PP_4843 +0.6 2.2 putative Urea ABC transporter, permease protein compare
PP_2883 +0.6 1.1 conserved protein of unknown function compare
PP_2603 +0.6 2.1 conserved protein of unknown function compare
PP_1699 +0.6 1.6 2-pyrone-4,6-dicarboxylic acid hydrolase compare
PP_5633 +0.6 2.1 conserved protein of unknown function compare
PP_0951 +0.6 2.5 Ribosome hibernation promoting factor compare
PP_3035 +0.6 1.4 conserved protein of unknown function compare
PP_0805 +0.6 2.9 Outer membrane efflux protein compare
PP_1541 +0.6 2.6 putative Methyltransferase compare
PP_0640 +0.6 1.4 conserved protein of unknown function compare
PP_2103 +0.6 1.6 conserved protein of unknown function compare
PP_0322 +0.6 2.7 serine hydroxymethyltransferase compare
PP_1435 +0.6 1.7 DNA repair protein RecO compare
PP_2247 +0.6 1.6 putative Endoribonuclease compare
PP_5223 +0.6 2.4 regulator of nucleotide diphosphokinase compare
PP_1028 +0.6 1.3 Transcriptional regulator, LysR family compare
PP_4642 +0.6 0.6 Cyclic diguanosine monophosphate-binding protein compare
PP_2341 +0.6 1.1 6-carboxy-5,6,7,8-tetrahydropterin synthase compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source L-Lysine in Pseudomonas putida KT2440

For carbon source L-Lysine across organisms