Experiment set10IT008 for Pseudomonas putida KT2440

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L-Glutamic acid monopotassium salt monohydrate carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_4099 +6.5 63.2 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1650 +6.3 54.1 Sensor protein GacS compare
PP_1656 +6.0 17.2 ATP:GTP 3'-pyrophosphotransferase compare
PP_4693 +5.7 12.7 RNA polymerase-binding transcription factor DksA compare
PP_1655 +3.7 5.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_4902 +3.3 15.2 Oligoribonuclease compare
PP_5232 +2.9 13.2 conserved protein of unknown function compare
PP_4171 +2.4 13.4 conserved exported protein of unknown function compare
PP_2299 +2.4 9.5 Trigger factor compare
PP_0674 +2.2 17.7 ADP/ATP ratio sensor and inhibitor of translation compare
PP_4710 +2.0 14.9 tRNA pseudouridine 55 synthase compare
PP_0785 +1.8 10.2 putative cysZ protein, required for sulfate transport compare
PP_1198 +1.8 5.2 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_2138 +1.6 3.0 conserved protein of unknown function compare
PP_4994 +1.6 7.7 conserved protein of unknown function compare
PP_t57 +1.6 3.0 tRNA-Arg compare
PP_1113 +1.5 11.9 Pyridoxal-phosphate dependent enzyme family protein compare
PP_1783 +1.5 2.2 dTDP-glucose pyrophosphorylase compare
PP_2889 +1.5 7.2 putative Transmembrane regulator PrtR compare
PP_0957 +1.5 2.5 D-arabinose 5-phosphate isomerase compare
PP_2403 +1.4 1.7 Chemotaxis protein CheY compare
PP_4993 +1.4 5.7 Glutathione synthetase compare
PP_1898 +1.4 4.3 MotA/TolQ/ExbB proton channel family protein compare
PP_1623 +1.3 9.1 RNA polymerase, sigma S (sigma 38) factor compare
PP_5114 +1.3 2.1 putative adenine methyltransferase compare
PP_2876 +1.3 9.6 Beta-lactamase compare
PP_4874 +1.3 1.9 50S ribosomal protein L9 compare
PP_5094 +1.2 3.1 putative enzyme with PLP binding domain compare
PP_0719 +1.2 1.5 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_2148 +1.2 9.3 transcription-repair coupling factor compare
PP_0575 +1.2 6.5 conserved membrane protein of unknown function compare
PP_1702 +1.2 4.4 Recombination-associated protein RdgC compare
PP_2144 +1.2 3.8 Transcriptional regulator, TetR family compare
PP_5313 +1.1 4.0 DNA-binding protein HU-alpha compare
PP_1313 +1.1 8.8 Transcriptional regulator, AraC family compare
PP_4050 +1.1 9.5 glycogen synthase compare
PP_4054 +1.1 3.0 conserved protein of unknown function compare
PP_2231 +1.1 1.8 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_0566 +1.1 2.0 translation-related factor compare
PP_4172 +1.1 6.6 conserved exported protein of unknown function compare
PP_0119 +1.1 3.4 putative zinc uptake regulation protein ZUR compare
PP_4173 +1.1 6.0 Sensor histidine kinase/response regulator compare
PP_2387 +1.0 3.2 conserved protein of unknown function compare
PP_3691 +1.0 9.9 DNA helicase-related protein compare
PP_0959 +1.0 3.1 phospholipid ABC transporter compare
PP_0495 +1.0 5.9 type 1 L-asparaginase compare
PP_0138 +1.0 3.8 conserved membrane protein of unknown function compare
PP_5309 +1.0 1.6 oxidative and nitrosative stress transcriptional dual regulator compare
PP_2223 +1.0 5.8 conserved protein of unknown function compare
PP_0129 +1.0 6.6 GGDEF domain protein compare
PP_0574 +0.9 7.3 DNA-binding response regulator, LuxR family compare
PP_0140 +0.9 3.7 conserved protein of unknown function compare
PP_5310 +0.9 4.1 junction-specific ATP-dependent DNA helicase compare
PP_1214 +0.9 2.6 putative transcriptional regulatory protein compare
PP_1605 +0.9 1.7 Ribonuclease HII compare
PP_0261 +0.9 4.8 adenosine-3'(2'),5'-bisphosphate nucleotidase compare
PP_2000 +0.9 0.6 amidophosphoribosyl transferase compare
PP_4204 +0.9 4.0 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor compare
PP_2389 +0.9 5.5 conserved protein of unknown function compare
PP_1562 +0.8 2.4 putative Phage terminase, small subunit compare
PP_5053 +0.8 4.0 Protein-export protein SecB compare
PP_4808 +0.8 1.4 23S rRNA m3psi1915 methyltransferase compare
PP_1261 +0.8 2.4 2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase compare
PP_2759 +0.8 1.6 ribose ABC transporter - ATP-binding subunit compare
PP_4100 +0.8 3.0 Transcriptional regulator, Cro/CI family compare
PP_0910 +0.8 3.5 conserved exported protein of unknown function compare
PP_4273 +0.8 1.7 Transcriptional regulator, MerR family compare
PP_0892 +0.8 4.7 Phospholipase family protein compare
PP_0135 +0.8 1.7 conserved exported protein of unknown function compare
PP_4317 +0.8 1.8 conserved protein of unknown function compare
PP_1906 +0.8 3.5 ribosomal large subunit pseudouridine synthase C compare
PP_1058 +0.8 6.7 conserved protein of unknown function compare
PP_0725 +0.8 4.0 conserved hypothetical TPR repeat protein compare
PP_4098 +0.8 1.6 UvrABC system protein C compare
PP_5633 +0.8 2.2 conserved protein of unknown function compare
PP_3164 +0.8 1.5 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
PP_1268 +0.8 1.8 putative HtrA suppressor protein sohA compare
PP_0142 +0.8 2.0 putative ABC transporter, permease protein compare
PP_0274 +0.8 1.9 putative transcriptional regulator containing HTH domain compare
PP_4479 +0.7 3.3 arginine N-succinyltransferase, subunit beta compare
PP_5247 +0.7 2.6 conserved protein of unknown function compare
PP_3754 +0.7 2.8 Beta-ketothiolase BktB compare
PP_4738 +0.7 2.8 conserved exported protein of unknown function compare
PP_4952 +0.7 1.6 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_5039 +0.7 2.6 conserved protein of unknown function compare
PP_2132 +0.7 2.0 Universal stress protein compare
PP_5294 +0.7 3.6 Ribonuclease PH compare
PP_2229 +0.7 2.8 putative K(+)/H(+) antiporter subunit C compare
PP_2147 +0.7 2.7 conserved exported protein of unknown function compare
PP_3766 +0.7 2.3 Lactoylglutathione lyase compare
PP_2878 +0.7 1.8 conserved protein of unknown function compare
PP_1041 +0.7 1.9 twin arginine protein export complex subunit compare
PP_0258 +0.7 2.3 regulator of murein cross-linking compare
PP_3312 +0.7 1.1 putative Heat shock protein compare
PP_0066 +0.7 3.3 Ribosomal RNA small subunit methyltransferase B compare
PP_2090 +0.7 2.0 Uroporphyrinogen-III C-methyltransferase compare
PP_2388 +0.7 2.3 Transporter, LysE family compare
PP_3824 +0.7 1.5 conserved exported protein of unknown function compare
PP_0880 +0.7 2.6 dipeptide ABC transporter - putative membrane subunit compare
PP_0673 +0.7 1.4 conserved protein of unknown function compare
PP_3806 +0.7 2.3 Hydrolase, isochorismatase family compare
PP_4519 +0.7 5.1 Agglutination protein compare
PP_0139 +0.7 1.8 putative Lipoprotein compare
PP_4215 +0.7 3.0 pyoverdine biosynthesis related protein compare
PP_5453 +0.7 0.9 conserved protein of unknown function compare
PP_1583 +0.7 1.9 putative Structural protein P5 compare
PP_1733 +0.6 1.0 membrane ATPase of the MinC-MinD-MinE system compare
PP_5469 +0.6 2.2 putative SAM-dependent methyltransferase compare
PP_5505 +0.6 1.6 conserved transmembrane protein of unknown function compare
PP_1352 +0.6 2.1 UPF0234 protein PP_1352 compare
PP_0211 +0.6 2.2 conserved protein of unknown function compare
PP_2101 +0.6 2.3 DNA-binding response regulator in two-component regulatory system with EvgS compare
PP_4109 +0.6 1.5 conserved protein of unknown function compare
PP_2046 +0.6 2.1 Transcriptional regulator, LysR family compare
PP_3627 +0.6 3.4 conserved protein of unknown function compare
PP_5491 +0.6 1.1 conserved protein of unknown function with SEC-C motif domain compare
PP_0806 +0.6 5.7 putative Surface adhesion protein compare
PP_2333 +0.6 2.0 GntR family transcriptional regulator compare
PP_3971 +0.6 0.8 conserved protein of unknown function compare
PP_1922 +0.6 2.9 conserved protein of unknown function compare
PP_2899 +0.6 0.6 conserved exported protein of unknown function compare
PP_0406 +0.6 3.3 Nucleotidyltransferase family protein compare
PP_4682 +0.6 1.7 conserved protein of unknown function containing tetratricopeptide repeat domain compare
PP_1216 +0.6 1.2 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_5552 +0.6 1.3 conserved protein of unknown function compare
PP_0804 +0.6 3.2 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_0856 +0.6 1.4 conserved lipoprotein of unknown function compare
PP_0803 +0.6 3.8 Protein secretion ABC efflux system, membrane fusion protein compare
PP_5000 +0.6 1.4 peptidase component of the ATP-dependent HslVU protease compare
PP_1234 +0.6 4.0 putative permease compare
PP_2711 +0.6 3.0 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_0401 +0.6 1.4 Ribosomal RNA small subunit methyltransferase A compare
PP_3034 +0.6 0.9 putative Regulator protein compare
PP_1364 +0.6 4.1 conserved exported protein of unknown function compare
PP_4560 +0.6 2.2 putative Ribonuclease BN compare
PP_3989 +0.6 2.2 DNA-cytosine methyltransferase compare
PP_5058 +0.6 2.5 Carboxy-terminal-processing protease compare
PP_0065 +0.6 1.6 NAD-binding component of TrK potassium transporter compare
PP_3481 +0.6 1.1 conserved exported protein of unknown function compare
PP_5435 +0.6 2.7 conserved protein of unknown function compare
PP_2023 +0.6 2.5 Glutathione S-transferase family protein compare
PP_1644 +0.6 1.8 NAD(P)H dehydrogenase (quinone) compare
PP_2840 +0.6 2.1 putative Membrane protein compare
PP_3880 +0.6 1.1 conserved exported protein of unknown function compare
PP_5110 +0.6 0.8 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_4480 +0.6 3.6 arginine N-succinyltransferase, subunit alpha compare
PP_0398 +0.6 1.2 Thiosulfate sulfurtransferase GlpE compare
PP_0001 +0.5 1.0 probable chromosome-partitioning protein compare
PP_3014 +0.5 1.1 conserved exported protein of unknown function compare
PP_2291 +0.5 1.5 conserved protein of unknown function compare
PP_5027 +0.5 0.9 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_5582 +0.5 0.9 conserved protein of unknown function compare
PP_0260 +0.5 2.8 ADP-sugar pyrophosphorylase compare
PP_2499 +0.5 0.7 conserved protein of unknown function compare
PP_0414 +0.5 2.8 Polyamine ABC transporter, permease protein compare
PP_2894 +0.5 2.3 conserved protein of unknown function compare
PP_4608 +0.5 2.4 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_0805 +0.5 3.4 Outer membrane efflux protein compare
PP_0168 +0.5 4.7 putative surface adhesion protein compare
PP_2073 +0.5 1.4 Acetyltransferase, GNAT family compare
PP_2646 +0.5 2.2 conserved protein of unknown function compare
PP_3460 +0.5 1.1 quinohemoprotein amine dehydrogenase, gamma subunit compare
PP_0167 +0.5 4.4 Toxin secretion ATP-binding protein compare
PP_4419 +0.5 1.8 transposase compare
PP_4486 +0.5 2.8 lysine / arginine / ornithine ABC transporter - periplasmic binding protein compare
PP_0117 +0.5 2.6 Zn(2+) ABC transporter - permease subunit compare
PP_4165 +0.5 2.9 conserved protein of unknown function compare
PP_1568 +0.5 0.9 conserved protein of unknown function compare
PP_0789 +0.5 2.1 N-acetyl-anhydromuramyl-L-alanine-amidase compare
PP_4311 +0.5 2.9 putative D-amino acid dehydrogenase 2 small subunit compare
PP_3922 +0.5 3.4 putative inner membrane peptidase compare
PP_1249 +0.5 2.2 conserved protein of unknown function, DUF4223 family compare
PP_2228 +0.5 2.6 putative K(+)/H(+) antiporter subunit D compare
PP_5528 +0.5 1.4 conserved protein of unknown function compare
PP_2340 +0.5 1.9 conserved protein of unknown function compare
PP_1776 +0.5 4.1 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_4484 +0.5 3.4 histidine / lysine / arginine / ornithine ABC transporter - permease subunit compare
PP_0132 +0.5 2.1 Alginate biosynthesis sensor protein KinB compare
PP_5177 +0.5 2.4 spermidine/putrescine ABC transporter - permease subunit compare
PP_5140 +0.5 1.5 Transcriptional regulator, MerR family compare
PP_4224 +0.5 1.9 Sensor histidine kinase compare
PP_3141 +0.5 1.9 Glycosyl transferase, WecB/TagA/CpsF family compare
PP_2681 +0.5 0.7 coenzyme PQQ synthesis protein D compare
PP_0257 +0.5 1.5 protein sulfur transferase compare
PP_5598 +0.5 1.7 conserved protein of unknown function compare
PP_0191 +0.5 1.3 Transcriptional regulatory protein AlgQ compare
PP_1817 +0.5 2.2 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_2361 +0.5 2.0 putative chaperone protein compare
PP_4687 +0.5 2.1 Hemin import ATP-binding protein HmuV compare
PP_2568 +0.5 0.8 Ring-cleaving dioxygenase compare
PP_1355 +0.5 4.4 Muropeptide permease AmpG compare
PP_2145 +0.5 1.8 beta-N-acetylglucosaminidase compare
PP_4844 +0.5 1.4 putative Urea ABC transporter, ATP-binding protein compare
PP_4861 +0.5 2.0 conserved protein of unknown function compare
PP_1543 +0.5 2.8 conserved protein of unknown function compare
PP_5181 +0.5 3.8 spermidine/putrescine ABC transporter - periplasmic subunit compare
PP_5099 +0.5 1.7 conserved protein of unknown function compare
PP_3591 +0.5 1.9 Delta 1-piperideine-2-carboxylate reductase compare
PP_0640 +0.5 1.5 conserved protein of unknown function compare
PP_5674 +0.5 1.1 conserved protein of unknown function compare


Specific Phenotypes

For 13 genes in this experiment

For carbon source L-Glutamic acid monopotassium salt monohydrate in Pseudomonas putida KT2440

For carbon source L-Glutamic acid monopotassium salt monohydrate across organisms