Experiment set10IT004 for Escherichia coli BW25113

Compare to:

LB Aerobic with Phenazine ethosulfate 0.0000625 mM

200 most important genes:

  gene name fitness t score description  
b1412 azoR -4.7 -3.3 acyl carrier protein phosphodiesterase (NCBI) compare
b4062 soxS -4.6 -4.5 DNA-binding transcriptional dual regulator (NCBI) compare
b0462 acrB -4.5 -6.9 multidrug efflux system protein (NCBI) compare
b0463 acrA -4.4 -5.3 multidrug efflux system (NCBI) compare
b1679 sufE -4.4 -3.0 cysteine desufuration protein SufE (NCBI) compare
b4063 soxR -4.3 -5.2 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing (NCBI) compare
b2617 smpA -4.2 -2.9 small membrane protein A (VIMSS) compare
b1426 ydcH -3.9 -2.2 orf, hypothetical protein (VIMSS) compare
b1683 ynhE -3.9 -6.5 orf, hypothetical protein (VIMSS) compare
b1682 sufC -3.9 -3.8 cysteine desulfurase ATPase component (NCBI) compare
b3908 sodA -3.4 -6.5 superoxide dismutase, manganese (VIMSS) compare
b1681 sufD -3.4 -5.1 component of SufBCD complex (NCBI) compare
b3035 tolC -3.3 -2.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3844 fre -3.3 -3.2 NAD(P)H-flavin reductase (NCBI) compare
b2790 yqcA -3.2 -4.3 flavodoxin (NCBI) compare
b1680 sufS -3.2 -4.8 selenocysteine lyase (NCBI) compare
b1907 tyrP -3.1 -2.1 tyrosine transporter (NCBI) compare
b3414 gntY -3.1 -2.1 predicted gluconate transport associated protein (NCBI) compare
b4546 ypeB -3.0 -1.7 hypothetical protein (NCBI) compare
b1961 dcm -2.9 -2.0 DNA cytosine methylase (NCBI) compare
b1855 lpxM -2.8 -3.9 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b3924 fpr -2.8 -6.5 ferredoxin-NADP reductase (NCBI) compare
b4408 csrB -2.8 -3.3 CsrA-binding sRNA, antagonizing CsrA regulation (NCBI) compare
b1677 lpp -2.7 -1.8 murein lipoprotein (NCBI) compare
b3163 nlpI -2.6 -2.6 hypothetical protein (NCBI) compare
b2494 yfgC -2.6 -6.1 predicted peptidase (NCBI) compare
b3764 yifE -2.6 -4.6 hypothetical protein (NCBI) compare
b0015 dnaJ -2.5 -6.1 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b3032 cpdA -2.5 -6.3 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b2501 ppk -2.5 -5.8 polyphosphate kinase (NCBI) compare
b2512 yfgL -2.4 -3.7 protein assembly complex, lipoprotein component (NCBI) compare
b0429 cyoD -2.4 -4.0 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b4551 yheV -2.3 -2.8 hypothetical protein (NCBI) compare
b3149 yraO -2.3 -5.6 DnaA initiator-associating factor for replication initiation (NCBI) compare
b1518 lsrG -2.3 -1.4 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b1231 tyrT -2.3 -1.3 tRNA-Tyr (NCBI) compare
b2436 hemF -2.3 -4.5 coproporphyrinogen III oxidase (NCBI) compare
b4410 ecnA -2.2 -1.8 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b1446 ydcY -2.2 -2.1 hypothetical protein (NCBI) compare
b3792 wzxE -2.1 -2.1 O-antigen translocase (NCBI) compare
b0431 cyoB -2.1 -7.9 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3617 kbl -2.1 -4.8 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b2281 nuoI -2.1 -1.4 NADH dehydrogenase subunit I (NCBI) compare
b4480 hdfR -2.1 -4.6 transcriptional regulator HdfR (NCBI) compare
b4603 rseX -2.0 -1.1 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b0243 proA -2.0 -6.4 gamma-glutamyl phosphate reductase (NCBI) compare
b0406 tgt -2.0 -4.0 queuine tRNA-ribosyltransferase (NCBI) compare
b1685 ydiH -2.0 -1.5 predicted protein (RefSeq) compare
b2531 iscR -2.0 -1.3 DNA-binding transcriptional repressor (NCBI) compare
b1108 ycfP -2.0 -2.9 orf, hypothetical protein (VIMSS) compare
b1438 ydcQ -2.0 -2.6 predicted DNA-binding transcriptional regulator (RefSeq) compare
b3961 oxyR -2.0 -8.2 DNA-binding transcriptional dual regulator (NCBI) compare
b2142 yohK -1.9 -4.8 predicted inner membrane protein (NCBI) compare
b1524 yneH -1.9 -1.0 predicted glutaminase (NCBI) compare
b4000 hupA -1.9 -3.8 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b0122 yacC -1.9 -4.2 orf, hypothetical protein (VIMSS) compare
b2906 visC -1.9 -3.6 hypothetical protein (NCBI) compare
b1830 prc -1.9 -1.8 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b2450 yffS -1.9 -1.7 CPZ-55 prophage; predicted protein (RefSeq) compare
b1767 ansA -1.9 -4.3 cytoplasmic asparaginase I (NCBI) compare
b0428 cyoE -1.9 -5.1 protoheme IX farnesyltransferase (NCBI) compare
b2051 wcaH -1.9 -1.8 GDP-mannose mannosyl hydrolase (VIMSS) compare
b2426 ucpA -1.9 -2.0 putative oxidoreductase (VIMSS) compare
b1192 ldcA -1.8 -3.9 L,D-carboxypeptidase A (NCBI) compare
b2814 metZ -1.8 -1.4 tRNA-Met (NCBI) compare
b1361 ydaW -1.8 -1.0 orf, hypothetical protein (VIMSS) compare
b0432 cyoA -1.8 -7.8 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b3181 greA -1.8 -3.1 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b3199 yrbK -1.8 -2.1 hypothetical protein (NCBI) compare
b1293 sapB -1.8 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2017 yefM -1.7 -1.6 orf, hypothetical protein (VIMSS) compare
b0178 hlpA -1.7 -3.2 periplasmic chaperone (NCBI) compare
b1823 cspC -1.7 -1.2 stress protein, member of the CspA-family (NCBI) compare
b0145 dksA -1.7 -1.6 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0685 ybfE -1.7 -2.3 orf, hypothetical protein (VIMSS) compare
b1839 yebY -1.7 -2.3 hypothetical protein (NCBI) compare
b3742 mioC -1.7 -3.9 flavodoxin (NCBI) compare
b0990 cspG -1.7 -1.1 DNA-binding transcriptional regulator (NCBI) compare
b2571 rseB -1.7 -4.5 periplasmic negative regulator of sigmaE (NCBI) compare
b3884 yihW -1.7 -4.6 putative DEOR-type transcriptional regulator (VIMSS) compare
b2424 cysU -1.6 -2.0 sulfate/thiosulfate transporter subunit (NCBI) compare
b0998 torD -1.6 -1.2 chaperone protein TorD (NCBI) compare
b1871 yecP -1.6 -3.2 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b2423 cysW -1.6 -3.8 sulfate/thiosulfate transporter subunit (NCBI) compare
b0028 fkpB -1.6 -4.0 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (NCBI) compare
b2113 mrp -1.6 -3.9 putative ATPase (VIMSS) compare
b4208 cycA -1.6 -6.5 D-alanine/D-serine/glycine transporter (NCBI) compare
b1480 sra -1.5 -1.0 30S ribosomal subunit protein S22 (NCBI) compare
b4505 insX -1.5 -1.4 predicted IS protein (RefSeq) compare
b0053 surA -1.5 -1.8 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0427 yajR -1.5 -6.5 putative transport protein (VIMSS) compare
b0014 dnaK -1.5 -1.0 molecular chaperone DnaK (NCBI) compare
b2457 cchA -1.5 -2.8 detox protein (VIMSS) compare
b0430 cyoC -1.4 -3.0 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b1753 ynjA -1.4 -1.6 hypothetical protein (NCBI) compare
b1176 minC -1.4 -1.9 septum formation inhibitor (NCBI) compare
b0222 lpcA -1.4 -1.7 phosphoheptose isomerase (NCBI) compare
b0237 pepD -1.4 -4.5 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b1323 tyrR -1.4 -3.4 DNA-binding transcriptional dual regulator, tyrosine-binding (NCBI) compare
b3616 tdh -1.4 -3.2 L-threonine 3-dehydrogenase (NCBI) compare
b1857 yebL -1.4 -3.7 putative adhesin (VIMSS) compare
b1126 potA -1.4 -3.8 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b2314 dedD -1.4 -2.6 putative lipoprotein (VIMSS) compare
b2392 mntH -1.4 -4.0 manganese transport protein MntH (NCBI) compare
b1125 potB -1.4 -2.6 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b2276 nuoN -1.4 -3.3 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b0560 nohB -1.4 -1.5 DLP12 prophage; DNA packaging protein (NCBI) compare
b0723 sdhA -1.3 -6.5 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b0720 gltA -1.3 -4.0 citrate synthase (NCBI) compare
b1530 marR -1.3 -4.6 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b2889 idi -1.3 -3.5 isopentenyl-diphosphate delta-isomerase (NCBI) compare
b2209 eco -1.3 -1.5 ecotin precursor (NCBI) compare
b1848 yebG -1.3 -1.2 conserved protein regulated by LexA (NCBI) compare
b2808 gcvA -1.3 -1.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1778 yeaA -1.3 -1.7 methionine sulfoxide reductase B (NCBI) compare
b2284 nuoF -1.3 -2.6 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b0957 ompA -1.3 -2.3 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b1295 ymjA -1.3 -1.5 hypothetical protein (NCBI) compare
b0688 pgm -1.3 -1.5 phosphoglucomutase (NCBI) compare
b4701 sokX -1.3 -0.8 sok-related sRNA, function unknown (RefSeq) compare
b3649 rpoZ -1.3 -1.5 DNA-directed RNA polymerase subunit omega (NCBI) compare
b4139 aspA -1.3 -5.2 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b2422 cysA -1.2 -4.2 sulfate/thiosulfate transporter subunit (NCBI) compare
b3465 yhhF -1.2 -3.8 predicted methyltransferase (NCBI) compare
b4698 mgrR -1.2 -2.0 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b0242 proB -1.2 -2.1 gamma-glutamyl kinase (NCBI) compare
b1338 ydaJ -1.2 -3.0 putative aminohydrolase (EC 3.5.1.14) (VIMSS) compare
b2553 glnB -1.2 -2.7 regulatory protein P-II for glutamine synthetase (NCBI) compare
b0617 citD -1.2 -1.8 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b0724 sdhB -1.2 -3.8 succinate dehydrogenase, FeS subunit (NCBI) compare
b2948 yqgE -1.2 -1.9 orf, hypothetical protein (VIMSS) compare
b0149 mrcB -1.2 -6.6 penicillin-binding protein 1b (NCBI) compare
b4255 yjgD -1.2 -2.8 hypothetical protein (NCBI) compare
b0471 ybaB -1.2 -2.1 hypothetical protein (NCBI) compare
b0405 queA -1.2 -3.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (NCBI) compare
b1858 znuC -1.2 -3.2 high-affinity zinc transporter ATPase (NCBI) compare
b1640 ydhH -1.2 -1.9 anhydro-N-acetylmuramic acid kinase (NCBI) compare
b0386 proC -1.2 -2.1 pyrroline-5-carboxylate reductase (NCBI) compare
b4260 pepA -1.2 -5.9 leucyl aminopeptidase (NCBI) compare
b1476 fdnI -1.2 -0.9 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b0866 ybjQ -1.2 -1.1 hypothetical protein (NCBI) compare
b3890 yiiF -1.2 -1.8 orf, hypothetical protein (VIMSS) compare
b1144 ymfJ -1.2 -1.9 orf, hypothetical protein (VIMSS) compare
b2248 yfaX -1.2 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b1642 slyA -1.2 -1.3 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b3443 yrhA -1.2 -1.1 orf, hypothetical protein (VIMSS) compare
b1084 rne -1.1 -2.6 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b2425 cysP -1.1 -4.1 thiosulfate transporter subunit (NCBI) compare
b2794 yqcD -1.1 -3.8 hypothetical protein (NCBI) compare
b1055 yceA -1.1 -3.7 hypothetical protein (NCBI) compare
b1085 b1085 -1.1 -1.2 orf, hypothetical protein (VIMSS) compare
b1628 rsxB -1.1 -1.8 electron transport complex protein RnfB (NCBI) compare
b1726 yniB -1.1 -1.3 predicted inner membrane protein (NCBI) compare
b3745 yieM -1.1 -8.1 predicted von Willibrand factor containing protein (NCBI) compare
b3075 ebgR -1.1 -3.1 DNA-binding transcriptional repressor (NCBI) compare
b2479 gcvR -1.1 -2.4 transcriptional regulation of gcv operon (VIMSS) compare
b2634 yfjR -1.1 -2.4 CP4-57 prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b3973 birA -1.1 -1.9 biotin--protein ligase (NCBI) compare
b1278 pgpB -1.1 -1.6 phosphatidylglycerophosphatase B (NCBI) compare
b2620 smpB -1.1 -0.7 SsrA-binding protein (NCBI) compare
b1236 galU -1.1 -1.5 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2133 dld -1.1 -4.5 D-lactate dehydrogenase, FAD-binding, NADH independent (NCBI) compare
b1604 ydgH -1.1 -3.2 hypothetical protein (NCBI) compare
b2579 yfiD -1.1 -1.2 pyruvate formate lyase subunit (NCBI) compare
b2572 rseA -1.1 -3.2 anti-sigma factor (NCBI) compare
b1429 tehA -1.1 -0.7 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1658 purR -1.1 -2.8 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b1567 intK -1.1 -1.1 Qin prophage; predicted protein (RefSeq) compare
b4594 ymgJ -1.1 -1.0 hypothetical protein (RefSeq) compare
b0092 ddlB -1.0 -3.0 D-alanylalanine synthetase (NCBI) compare
b0877 ybjX -1.0 -4.1 hypothetical protein (NCBI) compare
b4203 rplI -1.0 -2.2 50S ribosomal protein L9 (NCBI) compare
b1442 ydcU -1.0 -2.7 predicted spermidine/putrescine transporter subunit (NCBI) compare
b1124 potC -1.0 -2.9 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b1731 cedA -1.0 -1.5 cell division modulator (RefSeq) compare
b4614 sokA -1.0 -1.5 no description compare
b3281 aroE -1.0 -6.6 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1724 ydiZ -1.0 -1.5 hypothetical protein (NCBI) compare
b3609 secB -1.0 -2.5 export protein SecB (NCBI) compare
b2141 yohJ -1.0 -1.7 hypothetical protein (NCBI) compare
b4557 yidD -1.0 -1.8 hypothetical protein (NCBI) compare
b1101 ptsG -1.0 -5.2 fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI) compare
b3761 trpT -1.0 -1.1 tRNA-Trp (NCBI) compare
b1853 yebK -1.0 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1114 mfd -1.0 -3.9 transcription-repair coupling factor (NCBI) compare
b4613 dinQ -1.0 -1.3 Damage inducible, function unknown (RefSeq) compare
b2804 fucU -1.0 -1.6 L-fucose mutarotase (NCBI) compare
b2642 yfjW -1.0 -0.7 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1317 ycjU -1.0 -2.3 predicted beta-phosphoglucomutase (NCBI) compare
b1954 dsrA -1.0 -1.5 regulatory antisense RNA (NCBI) compare
b0081 mraZ -1.0 -3.2 hypothetical protein (NCBI) compare
b0737 tolQ -1.0 -0.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1765 ydjA -1.0 -0.8 predicted oxidoreductase (NCBI) compare
b3752 rbsK -1.0 -5.1 ribokinase (NCBI) compare
b1693 aroD -1.0 -2.5 3-dehydroquinate dehydratase (NCBI) compare
b2168 fruK -1.0 -0.6 1-phosphofructokinase (NCBI) compare
b1175 minD -1.0 -2.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0506 allR -1.0 -2.1 DNA-binding transcriptional repressor (NCBI) compare
b1337 abgB -1.0 -1.8 predicted peptidase, aminobenzoyl-glutamate utilization protein (NCBI) compare
b2282 nuoH -1.0 -1.4 NADH dehydrogenase subunit H (NCBI) compare


Specific Phenotypes

For 24 genes in this experiment

For stress Phenazine ethosulfate in Escherichia coli BW25113

For stress Phenazine ethosulfate across organisms