Protein Info for UW163_RS20410 in Ralstonia solanacearum UW163

Annotation: aspartate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 23 to 437 (415 residues), 283.2 bits, E=1.5e-88

Best Hits

Swiss-Prot: 49% identical to BAUA_PSEAE: Beta-alanine--pyruvate aminotransferase (bauA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00822, beta-alanine--pyruvate transaminase [EC: 2.6.1.18] (inferred from 96% identity to rso:RS02393)

Predicted SEED Role

"Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.18)

MetaCyc Pathways

• superpathway of coenzyme A biosynthesis II (plants) (8/10 steps found)
• β-alanine degradation II (2/2 steps found)
• β-alanine biosynthesis II (4/6 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Propanoate metabolism
• Valine, leucine and isoleucine degradation
• beta-Alanine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.18

Protein Sequence (445 amino acids)

>UW163_RS20410 aspartate aminotransferase family protein (Ralstonia solanacearum UW163)
MKPAPHPLETTDLSYFWMPFTANRQYKAAPRLLVSAQGMYYRDADGHEVLDGTAGLWCVN
AGHSRKEIVDAIAVQAGTLDFAPTFQMGHPVAFRAAEKVAEIMPEGLNRIFFVNSGSEAV
DTALKIALAYHRARGEGQRTRFIGRERGYHGVGFGGISVGGISPNRKAFSANLIPGVDHL
PHTHAPEHNAFSKGQPAWGAHLADELERIVTLHDPSTIAAVIVEPLAGSTGVLVPPKGYL
ERLRALCDKHGILLIFDEVITGFGRLGAATASAFFGVTPDLLTMAKGINNAAVPMGAVAV
RQSLHDTVIDAGAPGAIELFHGYTYSAHPLAAAAAVAAIDLYRSEGLFERARDLSPAFEA
AAHSVKGAPYVKDIRNLGLVAGIELESRPGAVGARAYEVFLKCLERGVLVRYTGDTLAFS
PPLIISEAEIARIFDTVCTVLQEVA