Protein Info for UW163_RS11960 in Ralstonia solanacearum UW163

Annotation: DNA repair protein RecO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 PF11967: RecO_N" amino acids 41 to 113 (73 residues), 82.3 bits, see alignment E=1.9e-27 TIGR00613: DNA repair protein RecO" amino acids 42 to 187 (146 residues), 94.5 bits, see alignment E=3.4e-31 PF02565: RecO_C" amino acids 122 to 213 (92 residues), 51.6 bits, see alignment E=9.5e-18

Best Hits

Swiss-Prot: 97% identical to RECO_RALSO: DNA repair protein RecO (recO) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03584, DNA repair protein RecO (recombination protein O) (inferred from 98% identity to rsc:RCFBP_20412)

Predicted SEED Role

"DNA recombination and repair protein RecO" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (272 amino acids)

>UW163_RS11960 DNA repair protein RecO (Ralstonia solanacearum UW163)
MAGRSDPIPDEAAEWLAEEGIAGAAPRKGFPAARAEHRVAQQPAFVLHSYPYRETSLIID
VFTRDHGRIALVAKGAKRPHSALRAVLQTFQPLSLSWSGRGEVKTLTRAEWVGGMLPLGG
EGLLSGFYLNELLVKFVAREDGHAVLFSHYVDTLNKLAHGEPVAFTLRAFERVLLRETGF
AAQLDRCIDGEPVQPDGDYVYHPERGIRRVQPSDPSSWPVLRGQTLLDMERDDYSRPVTA
TQSRSLMRFLLHYHLHGTPLSTRQILIDLQKL