Protein Info for RPSI07_RS14040 in Ralstonia solanacearum PSI07

Annotation: aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 905 TIGR02414: aminopeptidase N" amino acids 14 to 904 (891 residues), 1235.9 bits, see alignment E=0 PF17900: Peptidase_M1_N" amino acids 76 to 191 (116 residues), 56.4 bits, see alignment E=8.6e-19 PF01433: Peptidase_M1" amino acids 231 to 456 (226 residues), 172.4 bits, see alignment E=2.2e-54 PF11940: DUF3458" amino acids 464 to 575 (112 residues), 91.3 bits, see alignment E=8.4e-30 PF17432: DUF3458_C" amino acids 580 to 905 (326 residues), 430.6 bits, see alignment E=8.5e-133

Best Hits

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.2

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (905 amino acids)

>RPSI07_RS14040 aminopeptidase N (Ralstonia solanacearum PSI07)
MLRTDTAVTIYRKDYAAPAFRIDDVALDIDLVPERTRVVSRLRMTRIRAGDTLTLVGEGL
ELAGITLDGQALPGIQPDGDTLTIEATPAQADTSFTLEITSFCNPAANSSLMGLYVSNGN
FFTQCEAEGFRKITYFLDRPDVMAVYTVTLRAAKADYPVLLSNGNLVSQRDLPDGRHEAV
WHDPFKKPSYLFALVAGTLECIEERIRSASGPEKLLQVWVEPHDLGKTRHAMDSLIHAIR
WDEQRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAETATDVDFANIESVV
GHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMAAQAAARAGNEAAAASARAVK
RIEDVRMLRQVQFPEDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTLLGREAF
RKGMDLYFQRHDGQAVACDDFRAAMADANGRDLTRFGRWYSQAGTPVVTVEGRHDAAART
YTLTLRQRCEPVGIETADSSLRKQPFHIPFAIGLLDAQGRDLPLRLRGEPASNAPLTTRV
LDFTEAEQTFVFEDVAEAPLPSLLRNFSAPVIVEYGYTTEQLTFLLAHDADPFNRWEAGQ
RLATDALLRMVADVQQRRAPQVDPALVEALRAVLADASLDPAFREQMLILPAETYLAERM
DVADPDAIHTARRTLRRTLAEALNAEFLRAYHDNTTDGPYTPDAVSAGKRALKNIALGYL
VETESAEALALAEQQYAAATNMTDRMGALAALVNSYAPGREAALADFYTRFADDALVIDK
WFALQAMQPGGAGKPTLATVRALMAHPAFTLRNPNRARALIFSFSSGNPAQFHAADGSGY
AFWAEQVLALDAINPQVSARLARALDRWRKYVPALRDAMHAALKRVAAHPSLSRDVREIV
GKALA