Protein Info for QEN71_RS41310 in Paraburkholderia sabiae LMG 24235

Annotation: proline racemase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF05544: Pro_racemase" amino acids 9 to 330 (322 residues), 399 bits, see alignment E=7.7e-124

Best Hits

Swiss-Prot: 56% identical to 4HYPE_AGRFC: 4-hydroxyproline 2-epimerase (Atu0398) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: None (inferred from 74% identity to bac:BamMC406_3225)

Predicted SEED Role

"Not a Proline racemase, nor 4-hydroxyproline epimerase [missing catalytic residues]" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>QEN71_RS41310 proline racemase family protein (Paraburkholderia sabiae LMG 24235)
MRWKKTLQVVGVHAEGEIGKVITGGVGKIPGDTVLDKMNYINEVDDSLRRLCVFEPRGAL
AMSFNLLVPPTRPEAHAGFFIMQADRAHPMSGSNSICVVTALLELGIVPMQEPETTVVLD
TAVGLVTARARCNDGRCESVSLEMMPAFVEELDLEIETPDFGKIKVDIAFGGVYYALVDV
DQVGMDINAENARRLADLGVKFADIVNEQVKVEHPLYPSINKIAYVMFRNRVADDVYQTC
TTLVPGRIDRSPCGTGSSANLATLAARGLADVGSRLVSRSAIGSEFKVEMLGRTEIGGRP
AVLPRIEGRGWVFSVEQLGVDPTDPFGTGFMVSDTWGEGFPQG