Protein Info for QEN71_RS40340 in Paraburkholderia sabiae LMG 24235

Annotation: saccharopine dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF05222: AlaDh_PNT_N
  • amino acids 5 to 138 (134 residues), 69.9 bits, E=1.3e-23

Best Hits

KEGG orthology group: None (inferred from 70% identity to bge:BC1002_6948)

Predicted SEED Role

"Saccharopine dehydrogenase [NAD+, L-lysine-forming] (EC 1.5.1.7)" in subsystem Lysine degradation (EC 1.5.1.7)

MetaCyc Pathways

• L-lysine biosynthesis IV (3/9 steps found)

KEGG Metabolic Maps

• Lysine biosynthesis
• Lysine degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.1.7

Protein Sequence (361 amino acids)

>QEN71_RS40340 saccharopine dehydrogenase (Paraburkholderia sabiae LMG 24235)
MNHIWLRSETKAFERRTPLMPVHAAMLLKKGVRVTVERSPMRCIQDEQYKAVGCEITGPH
SWQHAPPDTYILGLKELTEDVEELRHTHVYFAHAFKQQMGATAVLDRFRRGGGVLLDLEY
LRNFRGRELVSPGLSFWAGVCGAAVTLEIMQGKTSGDERVSLKKQFYNRFADLVEILEMK
IEKIRNVRILIAGARGMTGSGVRHLLNVLGLHSECWGRAETSSNLRSQILDFDVLFNCIR
SDDATPVLINSKMLEIPHRLSIIGDISCDAASPFNPLPIYQESTDFSKPVHRCGSGLNAI
DVVAIDNVASLLPVEASSAISSELFPFLCELFISSGCLADSAWGVAYQNFVDNLARPKNA
N