Protein Info for QEN71_RS39615 in Paraburkholderia sabiae LMG 24235
Annotation: glycine betaine/L-proline ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02000, glycine betaine/proline transport system ATP-binding protein [EC: 3.6.3.32] (inferred from 77% identity to rlt:Rleg2_4908)Predicted SEED Role
"L-proline glycine betaine ABC transport system permease protein ProV (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.32
Use Curated BLAST to search for 3.6.3.32
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (375 amino acids)
>QEN71_RS39615 glycine betaine/L-proline ABC transporter ATP-binding protein (Paraburkholderia sabiae LMG 24235) MADIQSGGIRIQHLYKIFGPKAASYVEAVKNGLSKAELLKETGHVLGLRDINLDIPAGSI QVIMGLSGSGKSTLIRHINRLIDPTAGEVLIGGVDVCKMGFRGLREFRRRQTAMVFQKFA LLPHRNVLDNVIYGLEICGVKRHAAVETAMRWIERVGLKGFEQRFPNQLSGGMQQRVGLA RALAMDAPVLLMDEAYSALDPLIRMDMQTVLLDLQKEIRKTIVFITHDLDEALRLGDQIA ILRDGCIVQQGTKQDIVLRPADEYVTNFVKQVNRGRVVCVESVMTPLRAGVASAGNHVVA GTTIEEAISMLTHNPAIEQLTVVGAEKQPLGSVSLRQLACALITSDERCDAIRVPAEARI RTEALPGVSLTPLER