Protein Info for QEN71_RS37415 in Paraburkholderia sabiae LMG 24235

Annotation: winged helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 973 PF00486: Trans_reg_C" amino acids 20 to 92 (73 residues), 56.9 bits, see alignment 2.7e-19 PF00931: NB-ARC" amino acids 130 to 329 (200 residues), 37.4 bits, see alignment E=2.6e-13 PF13401: AAA_22" amino acids 137 to 234 (98 residues), 31.5 bits, see alignment E=3e-11

Best Hits

KEGG orthology group: None (inferred from 89% identity to bph:Bphy_5717)

Predicted SEED Role

"Signal transduction response regulator / Disease resistance domain-containing protein / Tetratricopeptide repeat-containing protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (973 amino acids)

>QEN71_RS37415 winged helix-turn-helix domain-containing protein (Paraburkholderia sabiae LMG 24235)
MIQIGTLLVNFEQREIRQQGRSVRIGARAFDILEVLYRADGGIVSKDAIMDAVWPGSIVE
ENRLQVHIAALRKLFGADRELIKTVPGRGYLLVSENRHARAPERQTGTPTGGGLPACSAT
LVGRHVEVAQIVDRLGQASVVTLVGAGGIGKTCLAVHVARDMRERLGEPVCFVELAKAST
REAVLKTLASALRIDACDDYLTQERLADTLAAAPCLLVLDNAEHVIDVIATLVEALTARA
HTLRVLVTSREPLHIWAESVLRIEPLAVPASDSSARAILAHSAVELFLNRAKSVAPECGA
EENTIRLVGEICRRLEGLPLAIELAAARVATLGVEGVASRLDDRLNLLTGGLRSALPRHQ
TLRATFDWSYALLDATSRMLFRRLGFFAGAFTFDAVCTVATEPDMPVAAVISSLSELATK
SLLTVEFCGAIAQYRLTESTRAYAMEKLRDEGELQRIASRHMAYLQERIEHGKQPVGDLA
HGLPAAEPRLALDDARAAFEWAFSPGGNPALGVALAGSLVGTLMQGSLLHECHERSGRAL
AALDALPRGSVDTLCEMRLCSAYASTLLHSGGAMQEAGPLWKRVLLLARESRDEAFEARA
LWGAWNSTLACSDIHASFRFATRFQAFAERCGTPWQQILAAEMIAVSLHCFGEHEQARAR
LERAIAAMTELGSTAPGRMSLPVDPYNFGNGTLARIVWMQGHPEQAMQLVENVVNSIRPD
MLEPSLSHVLAVAAVPIALQCGELEAASRYLAVLQSQVALNRFEIWQAYAECHAGHLDIL
QGHPHAGLAKLEAALQRLMSFGFRRVLTPMIVICAETLVRAGRIAEARTRLDEALEFCQA
HGEHFFIAELQRVLGVAALEQARVLQSGGRASMADEFETKGRRHLLDAIQTSREQHAPML
EVRAVLNFADHLLERGESSRAASLLVDVSKRIDMQSNAPDVRRLAQLLHTTCAMHRSHDL
DADSGQPVMASDM