Protein Info for QEN71_RS37045 in Paraburkholderia sabiae LMG 24235

Annotation: PQQ-binding-like beta-propeller repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13360: PQQ_2" amino acids 95 to 236 (142 residues), 69.9 bits, see alignment E=4e-23 amino acids 475 to 569 (95 residues), 40.1 bits, see alignment E=5.1e-14 PF01011: PQQ" amino acids 112 to 138 (27 residues), 21.6 bits, see alignment (E = 2.1e-08) amino acids 162 to 195 (34 residues), 26.9 bits, see alignment (E = 4.3e-10) amino acids 473 to 496 (24 residues), 22.6 bits, see alignment (E = 1e-08) amino acids 512 to 541 (30 residues), 24.8 bits, see alignment (E = 2.1e-09) PF13570: PQQ_3" amino acids 150 to 179 (30 residues), 21.2 bits, see alignment (E = 4.6e-08) amino acids 485 to 525 (41 residues), 24 bits, see alignment 6.1e-09

Best Hits

KEGG orthology group: K00119, [EC: 1.1.99.-] (inferred from 88% identity to bxe:Bxe_B2415)

Predicted SEED Role

"Quino(hemo)protein alcohol dehydrogenase, PQQ-dependent (EC 1.1.99.8)" (EC 1.1.99.8)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.-, 1.1.99.8

Use Curated BLAST to search for 1.1.99.- or 1.1.99.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>QEN71_RS37045 PQQ-binding-like beta-propeller repeat protein (Paraburkholderia sabiae LMG 24235)
MNPSPRYLAVFVPLLVAALAAPTSRAADEVQNASTTTSAPMPSTFKPVSQAQLDGAASNS
SDWLHSNGSYAQTRFYPGTQINRTNVSKLRPVFIFQTAVNESMETAPIVTNGIMYITTSF
NHVYAVDAVTGKEFWHYKHKMGPVTTFCCGPNNRGVAISGDRLFMGTLDAKLVALDAKTG
SVVWETKIADPDEGYSETMAPTVVDGKVLIGTNGGEYGIRGFVKAFDANSGQLLWTFYTI
PDTGQEGVWATKDATGRDEKRDIAAEKKQLADKGGDFYKTLGGGVWMTPAIDRKTHTVFF
VVGNPSPDLYGAIRPGDNLYTDSLVAIDLDTGKYKWHYQYVPHDVWDLDAVSPPILIDVR
DTNGKMIPGVIHGGKTGHIYVHDRETGRLIRFSQAMIPQENMWTLPTAEGARMLPGANGG
VEWSPMAFDPQTRLAYAANLHQPMTYQVTDAPYPGGSKLWLGGAFKVIPSEEQWGKLSAV
NVDTGKVAWDFKTAQPLIGGVLVTGGGLVFNGEGNGLFRAFDASTGKKLWEFQCGAGVNA
PAVSYNVHGKQYVAVAAGGNTQLDFKRGNTVLVFALP