Protein Info for QEN71_RS36895 in Paraburkholderia sabiae LMG 24235

Annotation: cytochrome o ubiquinol oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 666 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 103 to 127 (25 residues), see Phobius details amino acids 144 to 170 (27 residues), see Phobius details amino acids 190 to 213 (24 residues), see Phobius details amino acids 227 to 253 (27 residues), see Phobius details amino acids 285 to 304 (20 residues), see Phobius details amino acids 316 to 335 (20 residues), see Phobius details amino acids 346 to 368 (23 residues), see Phobius details amino acids 381 to 403 (23 residues), see Phobius details amino acids 416 to 440 (25 residues), see Phobius details amino acids 452 to 473 (22 residues), see Phobius details amino acids 493 to 518 (26 residues), see Phobius details amino acids 591 to 627 (37 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 2 to 647 (646 residues), 1164.1 bits, see alignment E=0 PF00115: COX1" amino acids 56 to 504 (449 residues), 482.3 bits, see alignment E=7.3e-149

Best Hits

Swiss-Prot: 69% identical to CYOB_ECOLI: Cytochrome bo(3) ubiquinol oxidase subunit 1 (cyoB) from Escherichia coli (strain K12)

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 96% identity to bph:Bphy_5825)

MetaCyc: 69% identical to cytochrome bo3 subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (666 amino acids)

>QEN71_RS36895 cytochrome o ubiquinol oxidase subunit I (Paraburkholderia sabiae LMG 24235)
MFGKLTLDAIPYHEPIIMGTLGVVILGGLALLGAITYAGKWSYLWKEWITSVDHKRIGVM
YIILALIMLLRGFADAIMMRAQQAIAFGESAGYLPPHHYDQIFTAHGVIMIFFVATPLIL
GLMNVVVPLQLGARDVAYPFVNSLGFWLSVVGAVLVMISMFVGDFAATGWVAYPPLSELG
YSPTTGVDYYIWSLQVSGLGTTLSGINFIVTILRMRAPGLNLMKMPVFCWTALITNILIV
AVFPVLTGTLALLTMDRYLDMHFFTNELGGNAMMYINLIWVWGHPEVYILILPAFGAFSE
IIATFSGKPLFGYKSMVYATSSIGILSFFVWLHHFFTMGSGANVNAFFGIMTSIISVPTG
VKLFNWLFTMYRGRIRYHSSTLWTIGFMVTFAVGGMTGVLLAVPGADFVLHNSLFLVAHF
HNVIIGGVVFGCLAGISYWFPKVFGFTLDEFWGKVAFWCWLVGYWLAFTPLYILGFEGMT
RRMNHYSVPEWHVWLVVALVGAVVVGMGILALLIQFAVSIRNREQNRDVTGDPWNARSLE
WSTASPAPFYNFAHVPVITSLEQHWDDKQSGRAYVQPKQYEDIHMPRNTSAGFIIAAFSL
LFGFAMVWHMWLFAAVGLIGMIATFIARSYDQDVDYYVPAAEVERIENARFALLESDDRE
QIAEMA