Protein Info for QEN71_RS31860 in Paraburkholderia sabiae LMG 24235

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00561: Abhydrolase_1
  • amino acids 36 to 150 (115 residues), 47.4 bits, E=2.1e-16
• PF12697: Abhydrolase_6
  • amino acids 37 to 275 (239 residues), 52 bits, E=1.5e-17

Best Hits

KEGG orthology group: None (inferred from 93% identity to bph:Bphy_6598)

Predicted SEED Role

"Alpha/beta hydrolase fold (EC 3.8.1.5)" (EC 3.8.1.5)

MetaCyc Pathways

• 1,2-dichloroethane degradation (3/4 steps found)
• γ-hexachlorocyclohexane degradation (6/11 steps found)

KEGG Metabolic Maps

• 1,2-Dichloroethane degradation
• 3-Chloroacrylic acid degradation
• Naphthalene and anthracene degradation
• gamma-Hexachlorocyclohexane degradation

Isozymes

Compare fitness of predicted isozymes for: 3.8.1.5

Use Curated BLAST to search for 3.8.1.5

Protein Sequence (283 amino acids)

>QEN71_RS31860 alpha/beta hydrolase (Paraburkholderia sabiae LMG 24235)
MNMRTDHSLLADPQLSFATVASGICIPYVERGAGEPVVFVHGSLCDFRYWDAQIEPLSAH
FRCIAPSLSHYWPAVEACIQNEFGWQVHVAELAEFIVAMDLAPVHLVGHSRGGCVAFQLA
RDYPRLVKTLMLADPGGPLQLDGMTEASLPSPMNALRAKVAGMIEEGVVEPGLELFVDSV
SAPGAWRKSTDAFRMMAIDNASTLPKQFRDPLPAYSRDTAADVMCRTLLIDGQKSPRMFR
NNVDSLEGWIWRAERGTIAGASHGMNVANPAAFNRMLQSFIDS