Protein Info for QEN71_RS31645 in Paraburkholderia sabiae LMG 24235

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 transmembrane" amino acids 39 to 58 (20 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 143 to 162 (20 residues), see Phobius details amino acids 173 to 195 (23 residues), see Phobius details amino acids 215 to 239 (25 residues), see Phobius details amino acids 259 to 282 (24 residues), see Phobius details amino acids 304 to 328 (25 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 376 to 397 (22 residues), see Phobius details amino acids 417 to 438 (22 residues), see Phobius details amino acids 445 to 464 (20 residues), see Phobius details PF00324: AA_permease" amino acids 38 to 450 (413 residues), 358.1 bits, see alignment E=7.4e-111 PF13520: AA_permease_2" amino acids 38 to 435 (398 residues), 131.1 bits, see alignment E=5.5e-42

Best Hits

Swiss-Prot: 48% identical to GABP_BACSU: GABA permease (gabP) from Bacillus subtilis (strain 168)

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 92% identity to bug:BC1001_4659)

MetaCyc: 37% identical to aromatic amino acid:H+ symporter AroP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-56; TRANS-RXN-76; TRANS-RXN-77

Predicted SEED Role

"Aromatic amino acid transport protein AroP" in subsystem Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (494 amino acids)

>QEN71_RS31645 amino acid permease (Paraburkholderia sabiae LMG 24235)
MAESSTHVRAAGDGLERTQESTQESTSPRLGVALRQRHVTMISLGGIIGAGLFVGSSATL
STVGPAACLSYLVAGIVVLLVMRMLGEMALAVPGVGSFTEYARIGLGDWAGFTSGWLYWY
FWVIVVAVEAVAGAAILQRWIPAPVWMIGLVLLSVMTFINLMSVKSYGEFEFWFASIKVA
AIIVFIAIGAAWVFGFGHTHSAWSNLTAAKGFLPFGTMSVFAAVPTVIFAVGGAEIATIA
AAESDNPAKSVAAMTRSVILRVITFYVGSMFLIACIVPWTSIVTGHSPFVAALETMHVPG
AADIMNAIVLVAVLSALNSGLYVSSRILFRLAGRGDAPRALLRLTPSRVPRLAVLLSSVV
GYVAIIAAIVSPQGVFLFLVNASGAVMLFVYLATALAQIRIRRRLGAQGVQPELPMWLFP
WLSYAVVVAIIGVLLAMGMDAELRPQLMASVASLAVASAAWLLAAKRRPASDADNGTRTG
YLAAADGRALSGER