Protein Info for QEN71_RS31450 in Paraburkholderia sabiae LMG 24235

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 33 to 52 (20 residues), see Phobius details amino acids 73 to 93 (21 residues), see Phobius details amino acids 113 to 132 (20 residues), see Phobius details amino acids 143 to 166 (24 residues), see Phobius details amino acids 187 to 211 (25 residues), see Phobius details amino acids 228 to 249 (22 residues), see Phobius details amino acids 274 to 295 (22 residues), see Phobius details amino acids 319 to 340 (22 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 387 to 408 (22 residues), see Phobius details amino acids 415 to 433 (19 residues), see Phobius details PF00324: AA_permease" amino acids 5 to 407 (403 residues), 377.4 bits, see alignment E=1e-116 PF13520: AA_permease_2" amino acids 6 to 407 (402 residues), 146.6 bits, see alignment E=1.1e-46

Best Hits

Swiss-Prot: 60% identical to BAUD_PSEAE: Probable GABA permease (bauD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 80% identity to bvi:Bcep1808_6690)

MetaCyc: 56% identical to 4-aminobutanoate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-384; TRANS-RXN-57

Predicted SEED Role

"Aromatic amino acid transport protein AroP" in subsystem Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>QEN71_RS31450 amino acid permease (Paraburkholderia sabiae LMG 24235)
MKQRHVVMLSIGGSIGAGLFVGSGHAIAEAGPAAIVAYVLASLLVVLVMRMLGEMACAMP
DSGSFSTYAGKAIGPWAGFMIGWMYWWFWVLVLPIEATAAANILNSWFPQIELWKFCLAV
TCLLTVANLASVKHYGELEFWFSVVKVLAIVIFIACGAAALAGFVPHVHVNVSANLFGRG
GFAPNGWAPIAGAMLTTMFTFLGTEVVTIAAAESKDPAREISRAITSVVWRISLFYIGSI
AVIISILPWNDPALTQIGSYQAVLQALHVPYAKLMIDLLILVAVCSCLNSGLYTASRMIF
SLGARGQAPSVMTYTNRAGVPVFAVLASTLAAFGGVAANYLAPSYVFEALLSTTGSIALL
VYMVIAVSQLRLRARLHAQQKLKVRMWLHPFLGLFVVALIMGAFAVMVSGHAHRGEVVAT
LGLSAFLAYVGRLHQNRRKSGSS