Protein Info for QEN71_RS30055 in Paraburkholderia sabiae LMG 24235

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 730 PF20256: MoCoBD_2" amino acids 16 to 202 (187 residues), 67.3 bits, see alignment E=1.7e-22 amino acids 597 to 679 (83 residues), 72.6 bits, see alignment E=4.1e-24 PF02738: MoCoBD_1" amino acids 322 to 556 (235 residues), 108.1 bits, see alignment E=4e-35

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 95% identity to bph:Bphy_7214)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (730 amino acids)

>QEN71_RS30055 xanthine dehydrogenase family protein molybdopterin-binding subunit (Paraburkholderia sabiae LMG 24235)
MTTDTVDIQRPARRSFLKGAGTVAAVALTIGFEWTVTSRRAIAAQAPGAAFAPNAFLRVG
PDDSVTVIAKHVEMGQGAYTGIATIVAEELDADWSHVRVESAPADAKRYANLAFGTIQGT
GGSSAMANSWMQLREAGAKARAMLVTAAAQQWKVPASDLRTERGVVYHDASGKHATYGSL
TSAAASLPVPDNVTLKDPKNFKLIGSQAPRVDVPPKTDGTAQFTLDVTFPGMLVAVIQRP
PQFGATVRSFDASAAKAVPGVVKVVQVPRGVAVVGKSFWAAKQGRDALKVDWDDTNAEKR
SSADIMAEYRKAADKPGLPARTEGDAAKAIQGAARKICASYEFPYLAHAPMEPLDAVVKL
TANSCEIWAGDQFQTVDQANAARVAGLQPQQVSIHTLYAGGSFGRRANPGSDYIAEAVSI
AKALGANGTPVKLQWTREDDIHGGLYRPMYFHKLEAGLSRDGKLVGWQHRIVGQSIVADT
PFSGLIKNGIDGTSVEGAANIAYAIPNLSVELSTMRTGVPVLWWRVVGSSHTAFAVEAFI
DEAAHAAGKDPYQFRRDLLEHEPRMRGVLDLAAQKAGWSNAPLPSGKGRGIAVAEAFKTF
VAQVAEVSVDKDGKVKVDRVVCAVDCGTAINPDVIAAQVEGGIGFGLGAALYGAITLKDG
RIEQNNFDGYRVLRIDAMPKVEVHIVQSTLPPTGIGEPGVAPVGPAVANAIFAATGKRVY
ALPFSTENLA