Protein Info for QEN71_RS29400 in Paraburkholderia sabiae LMG 24235

Annotation: choline dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 564 PF00732: GMC_oxred_N" amino acids 12 to 303 (292 residues), 172.5 bits, see alignment E=1.2e-54 PF05199: GMC_oxred_C" amino acids 398 to 536 (139 residues), 146.2 bits, see alignment E=9.9e-47

Best Hits

KEGG orthology group: K00108, choline dehydrogenase [EC: 1.1.99.1] (inferred from 94% identity to bph:Bphy_3050)

Predicted SEED Role

"Choline dehydrogenase (EC 1.1.99.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.1.99.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.1

Use Curated BLAST to search for 1.1.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (564 amino acids)

>QEN71_RS29400 choline dehydrogenase (Paraburkholderia sabiae LMG 24235)
MSTTARKLEGEFDYIIIGAGTAGCVLANRLTEDPDVSVLLLEAGGKDDYHWIHVPVGYLY
CIGNPRTDWLYKTQAEPGLNGRALSYPRGRVLGGCSSINGMIYMRGQREDYDEWARVTND
ASWSWDAVLPVFKRSEDHHGGANEFHGAGGQWRVEKQRLKWKILETFAEAATETGIPATD
DFNRGNNTGVGYFDVNQKRGIRWNASKAFLRPALQRSNLTVITGAHTQRVVFEGKRCVGV
EYRGDNVEYIAKVRIEVIMSSGAVNSPQLLELSGVGNGARLQNLGIEVVKDLRGVGENLQ
DHLQLRMAYKVHGVRTLNTASAHWWGKMMIGLQYLLMQSGPMSMSPSQLGAFAKSDMNDR
SLTRPDLEYHVQPLSLDKFGEPLHRFNAFTASVCHLRPTSRGSVHIDSRDPHAAPLIAPN
YLSTDYDRHVAANALRLTRRIAAAPALQRYRPEEILPGIQFQTEEELQRAAGNVGTTIFH
PVGTCRMGTADDPGAVVDSRLRVIGVEGLRIVDASVMPTITSGNTNSPTLMIAERASDMI
RADRRARADSLSIETRAASPMSVA