Protein Info for QEN71_RS28470 in Paraburkholderia sabiae LMG 24235

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 PF00072: Response_reg" amino acids 7 to 117 (111 residues), 60.9 bits, see alignment E=2.6e-20 PF00196: GerE" amino acids 154 to 209 (56 residues), 47.7 bits, see alignment E=1.9e-16

Best Hits

Swiss-Prot: 41% identical to RCSB_ECOLI: Transcriptional regulatory protein RcsB (rcsB) from Escherichia coli (strain K12)

KEGG orthology group: K07687, two-component system, NarL family, captular synthesis response regulator RcsB (inferred from 97% identity to bph:Bphy_2872)

Predicted SEED Role

"Two-component response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (235 amino acids)

>QEN71_RS28470 response regulator (Paraburkholderia sabiae LMG 24235)
MQDPIRVVVADDHPVILFGAEQALLKFQGIRVVARAKQSTELVKILQTTPCDVLVTDLAM
PGGQYGDGLPLIGYLRRNFPDLPIVVLTMLENAALLKRLNELGVISVVNKSDDLSHIGLA
VQHVSRHIEYMSPSVKQALDTLRMNTGGKNDEVILSKRELEVVRLFVSGMTIKEISEQLN
RSIKTISTQKNTAMRKLGLERDSELFQYAQSNGLMNLSSYAPGEADTGAASPEGS