Protein Info for QEN71_RS24095 in Paraburkholderia sabiae LMG 24235

Annotation: NADH-quinone oxidoreductase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 689 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 39 to 61 (23 residues), see Phobius details amino acids 84 to 109 (26 residues), see Phobius details amino acids 121 to 138 (18 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details amino acids 183 to 202 (20 residues), see Phobius details amino acids 222 to 238 (17 residues), see Phobius details amino acids 259 to 277 (19 residues), see Phobius details amino acids 289 to 310 (22 residues), see Phobius details amino acids 317 to 339 (23 residues), see Phobius details amino acids 345 to 365 (21 residues), see Phobius details amino acids 384 to 405 (22 residues), see Phobius details amino acids 425 to 446 (22 residues), see Phobius details amino acids 498 to 523 (26 residues), see Phobius details amino acids 564 to 585 (22 residues), see Phobius details amino acids 638 to 657 (20 residues), see Phobius details amino acids 665 to 687 (23 residues), see Phobius details TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L" amino acids 9 to 683 (675 residues), 806.9 bits, see alignment E=8.7e-247 PF00662: Proton_antipo_N" amino acids 71 to 122 (52 residues), 75.1 bits, see alignment 4.9e-25 PF00361: Proton_antipo_M" amino acids 138 to 420 (283 residues), 263.8 bits, see alignment E=2.8e-82

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 99% identity to bph:Bphy_1998)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (689 amino acids)

>QEN71_RS24095 NADH-quinone oxidoreductase subunit L (Paraburkholderia sabiae LMG 24235)
MSTTLNENLLLAVALAPLAGSLIAGLFGNAIGRAGAHSVTILGVAISFVLSCIVFLDVLH
GGSFNATVYEWMTVGKVKFEVGFLVDTLTAMMMCVVTFVSLMVHVYTIGYMADEETGYQR
FFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFYFKRESAIYANMKAFLVNR
VGDFGFILGIGLILAYGGSMNYGDVFAKSHELASLSFPGTDWGLLTVACICLFIGAMGKS
AQFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVTRMSPLFELSDSALSFITVIGAIT
ALFMGFLGIVQNDIKRVVAYSTLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLGAG
SVIIGMHHDQDMRNMGGLRKYMPITWITSLIGSLALIGTPFFSGFYSKDSIIDAVKLSHL
PGSGFAYFAVVASVFVTALYSFRMYFMVFHGEERFRGPKHPDSPMGAEAAAHGHSHGHDD
HGHGHDDHHAHEPHETPWVVWLPLVLLAIPSIVIGAIAIGPMLYGDFFQHGVAFEKVIFI
GENHPALHEMAEEFQGWASMGLHAASGLPVWLALAGVVVSWFLYLKRPDLPAVIKRGFGP
IYTLLDNKYYMDKINEVVFARGAVAIGRGLWKEGDVVVIDGIVNGSARFIGWFASVIRFL
QSGYIYHYAFAMIIGMLGLLTLFVTLGGK