Protein Info for QEN71_RS23490 in Paraburkholderia sabiae LMG 24235

Annotation: formimidoylglutamate deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02022: formiminoglutamate deiminase
  • amino acids 6 to 462 (457 residues), 603.2 bits, E=1.5e-185
• PF01979: Amidohydro_1
  • amino acids 53 to 410 (358 residues), 95.9 bits, E=1.5e-31

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 91% identity to bph:Bphy_1809)

MetaCyc: 53% identical to formiminoglutamate deiminase subunit (Pseudomonas fluorescens)
Formimidoylglutamate deiminase. [EC: 3.5.3.13]

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)

KEGG Metabolic Maps

• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Protein Sequence (463 amino acids)

>QEN71_RS23490 formimidoylglutamate deiminase (Paraburkholderia sabiae LMG 24235)
MTQANQSLFADNAFLPEGWRQNVLLQWDASGALTSVTPDTQAPAGVARAHGPVLPGMPNL
HSHAFQRAMAGLTEYRANAVDSFWSWRDLMYRFAARITPEGLASIAQWLYIEMLKAGYTS
VCEFHYVHHMQDGQRYANEAELAQRVVDAAGASGIGITMLPVLYQYAGFGAQPPRDDQRR
FINTPDSLLALLHTLRRARPEHGALRYGVAPHSLRAVSNDSLRTLLNGLDAMSPGAPVHI
HIAEQTAEVDACIETEGARPVQWLLDRFDVDQRWCLVHATHIDANETANLAKSGAIAGLC
LTTEANLGDGIFPAHDYLEQQGRIGVGSDSHIGVDWRAELRLLEYGQRLSRRQRNVLAST
QTPRVADRLYAASLEGGALATGRAVGALKTGARADFMVLDANHPNIAEQTSDAWLSGAVF
CEHGETPVRDVYAGGAKVVDNRRHRDEEHAYANYRAALAELLK