Protein Info for QEN71_RS20330 in Paraburkholderia sabiae LMG 24235

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 PF13489: Methyltransf_23" amino acids 35 to 183 (149 residues), 37.6 bits, see alignment E=5.6e-13 PF01209: Ubie_methyltran" amino acids 46 to 140 (95 residues), 22 bits, see alignment E=2.8e-08 PF13847: Methyltransf_31" amino acids 47 to 139 (93 residues), 29 bits, see alignment E=2.6e-10 PF08241: Methyltransf_11" amino acids 51 to 139 (89 residues), 75.8 bits, see alignment E=1e-24 PF13649: Methyltransf_25" amino acids 51 to 137 (87 residues), 64.4 bits, see alignment E=3.8e-21 PF08242: Methyltransf_12" amino acids 51 to 139 (89 residues), 44 bits, see alignment E=9.5e-15

Best Hits

Swiss-Prot: 39% identical to YL8A_SCHPO: Uncharacterized methyltransferase-like C25B8.10 (SPAC25B8.10) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 61% identity to srr:SerAS9_0037)

Predicted SEED Role

"Methyltransferase (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (260 amino acids)

>QEN71_RS20330 class I SAM-dependent methyltransferase (Paraburkholderia sabiae LMG 24235)
MTHDTPHVHHAASEGYTKGADTYAKGRPDYPPELAAWLKDELALGPGKIAVDLGAGTGKF
TPRLVETGAQVIAVEPVAQMREKLAAALPQVDVREGTAQRLPLDDAAVDAVLCAQSFHWF
ASRESLAEIRRVLKPGGHLGLVWNVRDARVPWVAQLDAIVNAREGDAPRYHTGEWRNAFP
ADGFSALEERHMPHGHTGSAEDVIVTRVHSTSFILALPPEQWAEIERDVRALIASEPSLA
SCDVVTVPYVTYAFRATRID