Protein Info for QEN71_RS20255 in Paraburkholderia sabiae LMG 24235

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 PF00072: Response_reg" amino acids 4 to 112 (109 residues), 50.2 bits, see alignment E=2.7e-17 PF00486: Trans_reg_C" amino acids 149 to 224 (76 residues), 61.3 bits, see alignment E=7.8e-21

Best Hits

Swiss-Prot: 35% identical to REGX3_MYCS2: Sensory transduction protein regX3 (regX3) from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

KEGG orthology group: None (inferred from 93% identity to bph:Bphy_4665)

Predicted SEED Role

"Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>QEN71_RS20255 response regulator transcription factor (Paraburkholderia sabiae LMG 24235)
MRIAILQRDPIQGKLLEKIIVQAGHSCALYDDGLTLSKVLARSTVDLLVLDWHALRLSGT
DVLKAVRSVGGERMPVIFASADDSEESAVRAFVLGADDYVTLPARHAEFRERLCALLRRA
YPERYGKDSFDVGPYHFDTRRQLVTLRGAPVQLSGTQYRLASLFFSNIGRVLSRDHIFAM
VWGREFREVTRTIDSHVSRLRLLLQIEPHNDFRLQPVYKSGYRLLHLRTNEEVVVPHAEA
A