Protein Info for QEN71_RS20205 in Paraburkholderia sabiae LMG 24235

Annotation: ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 9 to 300 (292 residues), 215 bits, E=1.6e-67
• TIGR02152: ribokinase
  • amino acids 10 to 307 (298 residues), 310.3 bits, E=7.2e-97
• PF08543: Phos_pyr_kin
  • amino acids 176 to 280 (105 residues), 46.7 bits, E=2.8e-16

Best Hits

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 97% identity to bph:Bphy_4655)

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (2/3 steps found)
• ribose phosphorylation (1/2 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.15

Use Curated BLAST to search for 2.7.1.15

Protein Sequence (319 amino acids)

>QEN71_RS20205 ribokinase (Paraburkholderia sabiae LMG 24235)
MAMQQKEGRVVILGIYVTDLTFRADRMPLIGETVAGNAFKMGPGGKGSNQAVAAARAGAD
VVFVTRIGNDAFGAIARSTWDAEGITARASVIDGASTGAAHIFVDDITGKNAIIVASGAA
GMMNAGDVDAIEADIASARVFVTQLEQPVSAARRGLEVARKHGVTTVFNPAPALPLDDSI
FPLCDYITPNESETAALTGIEVRNVDDARRAADVLLKKGVRNVIVTLGEAGALLHSAEQS
VFVPAFQCGRVVETAGAGDGFTGGFAAALARGTDAVEAMRFGCALAGISVTRPGTAPSMP
MLAEVNEVLAQAGHTLSTH