Protein Info for QEN71_RS18265 in Paraburkholderia sabiae LMG 24235

Annotation: HPP family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 53 to 72 (20 residues), see Phobius details amino acids 79 to 99 (21 residues), see Phobius details amino acids 105 to 123 (19 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 153 to 170 (18 residues), see Phobius details PF04982: HPP" amino acids 56 to 176 (121 residues), 135.5 bits, see alignment E=1.1e-43 PF00571: CBS" amino acids 240 to 291 (52 residues), 58.2 bits, see alignment 8.2e-20 amino acids 319 to 373 (55 residues), 45.8 bits, see alignment 6.2e-16

Best Hits

KEGG orthology group: K07168, CBS domain-containing membrane protein (inferred from 92% identity to bph:Bphy_4486)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (389 amino acids)

>QEN71_RS18265 HPP family protein (Paraburkholderia sabiae LMG 24235)
MTRSPLIQWLARFYPAAMNVKWPERMRSALGALIGIAFTGGSMHLLLGPGANIPMLVAPM
GASAVLLFGVPASPLAQPWSIIGGNLVSATVGVACATLISDPVAAAALAVGVAIAAMFAF
RCVHPPSGAVALTAVLGGPAIHALGFRFVLEPILIQSAALLGAALVYHAVTGHRYPHATR
AAPAAPQVPASSSNITRDDLEAVLNRRGELLDIDPEDLETLFRETQMQAYARTFSELACR
DVMSAPVVSVSPDTTLRAAADLLQRHSIKALPVIDKRERVVGIVTRADLANKPKSVDLRL
MEALAARLFKRDTHRGRLVSTVMTTHVRTVATGTPIVELVPFFADDGHHHIPVIDKHDRL
VGIITQSDLIEGLYRQSQMQAQAQQRPAA