Protein Info for QEN71_RS15975 in Paraburkholderia sabiae LMG 24235

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 24 to 48 (25 residues), see Phobius details amino acids 61 to 84 (24 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 119 to 142 (24 residues), see Phobius details amino acids 167 to 187 (21 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details amino acids 249 to 273 (25 residues), see Phobius details amino acids 285 to 303 (19 residues), see Phobius details amino acids 315 to 334 (20 residues), see Phobius details amino acids 340 to 364 (25 residues), see Phobius details amino acids 376 to 395 (20 residues), see Phobius details amino acids 407 to 424 (18 residues), see Phobius details PF00083: Sugar_tr" amino acids 23 to 228 (206 residues), 72.8 bits, see alignment E=2.7e-24 amino acids 244 to 433 (190 residues), 45.5 bits, see alignment E=5.3e-16 PF07690: MFS_1" amino acids 29 to 377 (349 residues), 111.7 bits, see alignment E=3.9e-36 amino acids 290 to 426 (137 residues), 40.2 bits, see alignment E=2.1e-14

Best Hits

KEGG orthology group: K03761, MFS transporter, MHS family, alpha-ketoglutarate permease (inferred from 62% identity to mno:Mnod_3486)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>QEN71_RS15975 MFS transporter (Paraburkholderia sabiae LMG 24235)
MDTILPGVAQPSDTPLTRAQRKAIVAATLGTIVEFTDWIIYATFAALFSRHFFPANNDRV
SLLSAFAVFAVGFVMRPIGGALLGAYADRHGRKNGLALSVALMAGSSLVIAVCPGYESIG
IAAPLILVLARLIQGFAAGGEFGSASTFLIESSAPSRRGFAGSWQHFAVNAGVLVAALIG
AILTSLIDHAGMASWGWRVAFAIAGLLGFVALWVRLAVAETDAFRKSAATHQRTRHPFLV
IVREHRRAALRVIGIAMAGNLCVYLWLVLFPTLAHLRTGLPLHDAFNASVISIVVSLIAI
PFIGKLSDRIGRKPVLLVFAGGSALFAWPALHFLSNDFWSATAIVTIGMLLSSGFAATCA
TVMAEQFPAHVRATGVALPYAVSAALFGGTLPYIVTAMSSSGLSQYLWVYVATVCVVGFV
VYARMPETRGKVLD