Protein Info for QEN71_RS14195 in Paraburkholderia sabiae LMG 24235

Annotation: phosphonate metabolism transcriptional regulator PhnF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 TIGR02325: phosphonate metabolism transcriptional regulator PhnF" amino acids 14 to 250 (237 residues), 242.5 bits, see alignment E=2.3e-76 PF00392: GntR" amino acids 23 to 84 (62 residues), 56.1 bits, see alignment E=2.3e-19 PF07702: UTRA" amino acids 105 to 244 (140 residues), 90.8 bits, see alignment E=7.4e-30

Best Hits

KEGG orthology group: K02043, GntR family transcriptional regulator, phosphonate transport system regulatory protein (inferred from 97% identity to bph:Bphy_3772)

Predicted SEED Role

"Transcriptional regulator PhnF" in subsystem Alkylphosphonate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>QEN71_RS14195 phosphonate metabolism transcriptional regulator PhnF (Paraburkholderia sabiae LMG 24235)
MTSNDDAAPGAMLERGAGVAVWRQIEQILAKEIAASGFGEDGRLPSEGELARRFDVNRHT
IRRAMLGLAAQGLVSVEQGRGTFVQPGAIDYTIGRRTRFTENLRQQHHSPAGKMLSAARV
KADPTVAKALGLRAGAFVYRIESLHEADSVPLTYARNFYPAARFSDLPDVLERVGGITKA
MAEYGVTDYLRKWSRIGSVLPEPEVARRLGINRQQPVLWVENVDVDTEGTPIKYGFTHFA
ADRVQLMVEHDV