Protein Info for QEN71_RS13325 in Paraburkholderia sabiae LMG 24235

Annotation: cytochrome o ubiquinol oxidase subunit IV

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02847: cytochrome o ubiquinol oxidase subunit IV
  • amino acids 17 to 111 (95 residues), 108.2 bits, E=1.2e-35
• PF03626: COX4_pro
  • amino acids 22 to 96 (75 residues), 48.9 bits, E=3.6e-17

Best Hits

Swiss-Prot: 41% identical to CYOD_PSEAE: Cytochrome bo(3) ubiquinol oxidase subunit 4 (cyoD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 96% identity to bph:Bphy_3646)

MetaCyc: 38% identical to cytochrome bo terminal oxidase subunit IV (Pseudomonas putida KT2440)
RXN0-5268 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• glycerol-3-phosphate to cytochrome bo oxidase electron transfer (2/2 steps found)
• pyruvate to cytochrome bo oxidase electron transfer (2/2 steps found)
• succinate to cytochrome bo oxidase electron transfer (2/2 steps found)
• D-lactate to cytochrome bo oxidase electron transfer (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer II (1/2 steps found)
• proline to cytochrome bo oxidase electron transfer (1/2 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Protein Sequence (113 amino acids)

>QEN71_RS13325 cytochrome o ubiquinol oxidase subunit IV (Paraburkholderia sabiae LMG 24235)
MAHSNSHALDAEAGHGGIGGYVVGFVLAVVLTAAAFGIVMQGWLPAPSAPFVLAALAVVQ
IVVHLVFFLHMSVSTSGQRWNTLALAYTVLAVMFLVFGTVWVMHNVSMNMMSR