Protein Info for QEN71_RS12740 in Paraburkholderia sabiae LMG 24235

Annotation: ectoine/hydroxyectoine ABC transporter permease subunit EhuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 55 to 78 (24 residues), see Phobius details amino acids 85 to 104 (20 residues), see Phobius details amino acids 152 to 154 (3 residues), see Phobius details amino acids 162 to 168 (7 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details TIGR03003: ectoine/hydroxyectoine ABC transporter, permease protein EhuD" amino acids 3 to 214 (212 residues), 332.5 bits, see alignment E=1.2e-103 TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 12 to 109 (98 residues), 100.3 bits, see alignment E=7e-33 PF00528: BPD_transp_1" amino acids 35 to 214 (180 residues), 90 bits, see alignment E=8.5e-30

Best Hits

Swiss-Prot: 48% identical to Y4TG_SINFN: Probable amino-acid ABC transporter permease protein y4tG (NGR_a01520) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 91% identity to bxe:Bxe_C0067)

MetaCyc: 37% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"amino acid ABC transporter protein, permease protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (219 amino acids)

>QEN71_RS12740 ectoine/hydroxyectoine ABC transporter permease subunit EhuD (Paraburkholderia sabiae LMG 24235)
MEWDWSFARQILPILLQGLEITVLATVLGAVVAAVVGMVFAILRLSPNRAVANTTTAVVS
FIRGTPLLVQLYFVFYVLPDIGIKMPALAAGVLALGLHYGTYAAEVYRSGIENVPRGQWE
AAKACNLNPAQTWQHIILPEAVPPMLPALANYLISMFKETPLLSAITVLELMNEAKIIAN
TDYRYLEPMTLVGVLFLCISLIAVAAVRLLEKRFPPLGH