Protein Info for QEN71_RS11300 in Paraburkholderia sabiae LMG 24235

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 transmembrane" amino acids 29 to 46 (18 residues), see Phobius details amino acids 53 to 79 (27 residues), see Phobius details amino acids 89 to 112 (24 residues), see Phobius details amino acids 121 to 143 (23 residues), see Phobius details amino acids 163 to 180 (18 residues), see Phobius details amino acids 188 to 208 (21 residues), see Phobius details amino acids 229 to 257 (29 residues), see Phobius details amino acids 277 to 295 (19 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 334 to 357 (24 residues), see Phobius details amino acids 368 to 391 (24 residues), see Phobius details amino acids 402 to 420 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 20 to 218 (199 residues), 79.6 bits, see alignment E=2.5e-26 amino acids 212 to 420 (209 residues), 45.3 bits, see alignment E=6.1e-16 PF07690: MFS_1" amino acids 22 to 380 (359 residues), 91.3 bits, see alignment E=6.2e-30 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 23 to 413 (391 residues), 444 bits, see alignment E=2.6e-137

Best Hits

Swiss-Prot: 74% identical to CITH_KLEPN: Citrate-proton symporter (citH) from Klebsiella pneumoniae

KEGG orthology group: K03288, MFS transporter, MHS family, citrate/tricarballylate:H+ symporter (inferred from 95% identity to bge:BC1002_1260)

MetaCyc: 70% identical to propane-1,2,3-tricarboxylate-proton symporter (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-49

Predicted SEED Role

"metabolite/H symporter, major facilitator superfamily (MFS)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>QEN71_RS11300 MFS transporter (Paraburkholderia sabiae LMG 24235)
MHPSPHLSTGHSKAAAVFRVTAGNFLEQFDFFLFGFYATQIANVFFPTGSEFASLMMTFA
VFGAGFLMRPLGAIVLGAYIDDVGRRKGLIVTLAIMASGTILIAFVPGYATIGLLAPALV
LLGRLLQGFSAGAELGGVSVYLAEMATPGRKGFFTSWQSASQQVAIVVAAGLGFALNQWL
DASAIAAWGWRVPFFVGCMIVPFIFMLRRNLEETQEFKARQHRPGMKEVFGTLVQNWTVV
VAGMMLVAMTTTSFYLITVYAPTFGKTVLHLSTADSLLATLCVGVSNFVWLPIGGALSDK
IGRRPLLVGMTVLAIATSYPTLSLLAQAPSFVNMLLVLLWLSFMYGIYNGAMVVALTEVM
PVQVRVAGFSLAYSLATAVFGGFTPAISTALIHMTGDKAAPGYWMSLAAACALLATFALY
RRRAATLTPAL