Protein Info for QEN71_RS11065 in Paraburkholderia sabiae LMG 24235

Annotation: proline/glycine betaine ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 transmembrane" amino acids 42 to 60 (19 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details amino acids 91 to 113 (23 residues), see Phobius details amino acids 134 to 160 (27 residues), see Phobius details amino acids 213 to 235 (23 residues), see Phobius details amino acids 244 to 262 (19 residues), see Phobius details PF00528: BPD_transp_1" amino acids 105 to 267 (163 residues), 105.2 bits, see alignment E=1.8e-34

Best Hits

Swiss-Prot: 45% identical to OPUAB_BACSU: Glycine betaine transport system permease protein OpuAB (opuAB) from Bacillus subtilis (strain 168)

KEGG orthology group: K02001, glycine betaine/proline transport system permease protein (inferred from 92% identity to bph:Bphy_6869)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>QEN71_RS11065 proline/glycine betaine ABC transporter permease (Paraburkholderia sabiae LMG 24235)
MNSSVIGKFAENAVNFLFQHFRGGFDAFSAALGAVVKLLEDGLAAVPFVAMLVILVAFAL
WRRGVVFAVFVGAALMVIHYMGLWAQTVSTLALVIAATFFSLVIGVPLGIWGARNKRVEV
ILRSLLDFMQTMPAFVYLIPAVILFGLGRVPAVIATIVFSMPPVVRLTTLGIRQVREELL
EAGRSFGSTDSQLLWKIQLPNALPSIMAGVNQTIMMALSMVVVASMIGAGGLGEYVLSGI
QRLDIGIGFEGGLGVVLLAIVLDRLTESFGLKAKKSKRTVRTAKPAATSTAVRT