Protein Info for QEN71_RS10705 in Paraburkholderia sabiae LMG 24235

Annotation: mechanosensitive ion channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 871 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 153 to 173 (21 residues), see Phobius details amino acids 291 to 312 (22 residues), see Phobius details amino acids 325 to 346 (22 residues), see Phobius details amino acids 367 to 389 (23 residues), see Phobius details amino acids 400 to 421 (22 residues), see Phobius details amino acids 442 to 466 (25 residues), see Phobius details amino acids 480 to 506 (27 residues), see Phobius details amino acids 528 to 549 (22 residues), see Phobius details amino acids 568 to 589 (22 residues), see Phobius details amino acids 612 to 634 (23 residues), see Phobius details amino acids 640 to 658 (19 residues), see Phobius details PF21088: MS_channel_1st" amino acids 620 to 660 (41 residues), 24.2 bits, see alignment 2.7e-09 PF00924: MS_channel_2nd" amino acids 662 to 725 (64 residues), 67.8 bits, see alignment 7.4e-23

Best Hits

KEGG orthology group: None (inferred from 84% identity to bph:Bphy_5311)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (871 amino acids)

>QEN71_RS10705 mechanosensitive ion channel (Paraburkholderia sabiae LMG 24235)
MRKLLLICLLALFCAPAFSAVTATTSASGASATTVTLTPEQARQALQVLNDPKKRAQIED
TLTAIAAAGVLATPAAPASGASAAAATDSASGASATTAFKSNGLASQLVRQGAHWFKQGG
MTLKRSIAVLLDTSSARYWWNVQLSDPHERGKVFGVLLALIGTLLPAIALEWLARRLLRR
ARAAIIARREAREARDKAREAAADTAAATAADTAATATVQPDAAAAVPAPAKPAVSMSTP
PASSSASSDAQAATPDKSETPDNQQKEARSKRQAEHHWTTLQRLPSAALQLCLRMLPLVV
FVAAASALMSFFTDDGTIQDSALNGLIDLYVICRAIVIAAGFFLQPDAPGLRLLRLPDSW
ALFMQRWVIRVVSVIGAGGALIEIATALGLSDAAHLPLVKLLALVGHVMVSIMILQCRAP
ISALLRERTIDSSVESQRPVTILAHGLIDMWAWVAVFIVMALWFVWALDVHNGYRTLLHL
GGLSLAVLVAARVASIVLFGALGRVFRTQERDEDRSLIHQHAYRYYPLIRRVVSTLVIFI
SALVLFQVWGFDVWQFFRPGAIGHRLTSAVVTICVAAIVALVVWEIANVSVEKRLAQWTK
SGDLVRAARLRTLVPMLRTALFVAIALVVVLTGLSELGVNTAPLLASASIFGVALGFGSQ
KLVQDFITGIFLLMENAMQVGDWVTLAGVSGTVEYLSIRTVRLRGGDGSLFTVPFSSVST
VNNTNRGLGNAAVRVSIAYGQDVDLAIATLKEIGASLREDDQFKAGILSDFSFWGVDAVD
GASVTLAGQIQCRDTSRWGVQREFNRRIFDQFRAKGIEISNPQRSMLISSNPAGSGAETD
AGDDELQGPPRPTNAKENTQSDKPAPKAARH