Protein Info for QEN71_RS09800 in Paraburkholderia sabiae LMG 24235
Annotation: GH1 family beta-glucosidase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 45% identical to BGLS_AGRSA: Beta-glucosidase (abg) from Agrobacterium sp. (strain ATCC 21400)
KEGG orthology group: K05350, beta-glucosidase [EC: 3.2.1.21] (inferred from 94% identity to bph:Bphy_5434)Predicted SEED Role
"Beta-galactosidase (EC 3.2.1.23) / Beta-glucosidase/6-phospho-beta-glucosidase" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)
MetaCyc Pathways
- lactose degradation III (1/1 steps found)
- cellulose degradation II (fungi) (2/3 steps found)
- neolinustatin bioactivation (2/3 steps found)
- linamarin degradation (1/2 steps found)
- lotaustralin degradation (1/2 steps found)
- linustatin bioactivation (2/4 steps found)
- coumarin biosynthesis (via 2-coumarate) (2/5 steps found)
- xyloglucan degradation II (exoglucanase) (3/8 steps found)
- α-tomatine degradation (1/6 steps found)
- firefly bioluminescence (4/14 steps found)
KEGG Metabolic Maps
- Cyanoamino acid metabolism
- Galactose metabolism
- Glycosaminoglycan degradation
- Glycosphingolipid biosynthesis - ganglio series
- Other glycan degradation
- Phenylpropanoid biosynthesis
- Sphingolipid metabolism
- Starch and sucrose metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.23
Use Curated BLAST to search for 3.2.1.21 or 3.2.1.23
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (463 amino acids)
>QEN71_RS09800 GH1 family beta-glucosidase (Paraburkholderia sabiae LMG 24235) MAYDAVAPGSSQQSDPFTPSADSVLWRKDFLLGAATASYQIEGAVNEDGRLPSIWDTFSA TPGKVLAGDTGEVACDHYHRWESDLDLLTRLNFEAYRLSVAWPRVMDEAGRPNQKGLDFY KRLLGRLKEKGLQTFVTLYHWDMPQHLEDRGGWLNRETVYRFADYADLMSRELAGHVDAW MTLNEPWCSAFLGYGNGHHAPGLANVRYATQAMHHLLLAHGEATKVLRANDPASMKGIVA NVGRGTSASSSEADQRAAHLFEVQHNAWILDPLLKGEYPADLWELWPGAEPLVLEGDMQT IAAPLDFLGINYYFRTNVKSDGAHGFVDVPLPDVERTQMGWEVHPDGLRDLLTGFHGTYP NLPPIYITENGMASDDNVQDGHVDDPQRISFLKRHLAAVDQAVKQGVDIRGYFVWSLLDN FEWAFGYERRFGVVHVDYGTQQRTVKRSGELIAKFIEARSKKN