Protein Info for QEN71_RS09335 in Paraburkholderia sabiae LMG 24235

Annotation: cytochrome c oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 648 transmembrane" amino acids 40 to 61 (22 residues), see Phobius details amino acids 83 to 107 (25 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 167 to 191 (25 residues), see Phobius details amino acids 205 to 232 (28 residues), see Phobius details amino acids 253 to 276 (24 residues), see Phobius details amino acids 288 to 311 (24 residues), see Phobius details amino acids 321 to 347 (27 residues), see Phobius details amino acids 359 to 382 (24 residues), see Phobius details amino acids 397 to 418 (22 residues), see Phobius details amino acids 430 to 455 (26 residues), see Phobius details amino acids 474 to 496 (23 residues), see Phobius details amino acids 590 to 607 (18 residues), see Phobius details amino acids 612 to 630 (19 residues), see Phobius details TIGR02891: cytochrome c oxidase, subunit I" amino acids 29 to 534 (506 residues), 705.8 bits, see alignment E=1.5e-216 PF00115: COX1" amino acids 37 to 483 (447 residues), 500.2 bits, see alignment E=2.7e-154

Best Hits

Swiss-Prot: 45% identical to COX1_BACP3: Cytochrome c oxidase subunit 1 (ctaD) from Bacillus sp. (strain PS3)

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 95% identity to bph:Bphy_5490)

Predicted SEED Role

"Cytochrome c oxidase polypeptide I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (648 amino acids)

>QEN71_RS09335 cytochrome c oxidase subunit I (Paraburkholderia sabiae LMG 24235)
MPRGVVARGSAAEAHLRELWETPPGWRGWLSTVDHKRIGIRYLVTAFIFLILGGVEALIM
RVQLAQPNGTVLTPEQYNQLFTMHGVTMIFLYALPVLSGFSNYLWPLILGARDMAFPRLN
AFSYWIFLFAAIFLYASFPLGQAPDAGWFNYVPLSGLEYNTGPNIDVYALGMVLLGISTT
VGAVNFVVTLLRMRASGMSLDRIPVLVWGTMTASCGNLVAVPSVSLAFLMLWMDRRIGTH
FFDVLNGGRALLWQHLFWVFAHPWVYVVVLPAMGIVSDALPVFCRRPLVGYGPVALSTIA
TMLIGFVVWIHHMFATGIPALALSLFGAASMAIAVPSAIATFAWIATIWTGRPVFRVPFY
YFAGFVLLFVIGGVSGVMTAAVPFDWQLTDTYFVVAHLHYVLLGINVFPVIGGVYFWFPK
FTGRMMSERIGKLAFWVMFIGFNVAFFPMHIAGLLGMPRRIYTYAPEMGWSTVNLVTSVG
SFVLALGILIFLCDLLYSLRRGAPAGDNPWDAGTLEWSTTSPPPPYNFAVAPTVASRHPL
WEGRMEEEDEDGMRSSLKEGFILDQGREALGTTALEARPDVILKMPEDSYTPFVLSVFAT
LFFAALALLAWWFAAAMLIGCAASLVVWLWPERSLIQREPQRVQDAGN