Protein Info for QEN71_RS07390 in Paraburkholderia sabiae LMG 24235

Annotation: MFS family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 transmembrane" amino acids 20 to 45 (26 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 155 to 178 (24 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 239 to 258 (20 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 307 to 325 (19 residues), see Phobius details amino acids 331 to 354 (24 residues), see Phobius details amino acids 366 to 388 (23 residues), see Phobius details amino acids 400 to 418 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 20 to 216 (197 residues), 84.9 bits, see alignment E=8.9e-28 amino acids 220 to 416 (197 residues), 44.9 bits, see alignment E=1.2e-15 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 25 to 413 (389 residues), 461.5 bits, see alignment E=1.3e-142 PF07690: MFS_1" amino acids 60 to 377 (318 residues), 95.4 bits, see alignment E=5.3e-31 amino acids 266 to 425 (160 residues), 54.7 bits, see alignment E=1.2e-18

Best Hits

Swiss-Prot: 70% identical to KGTP_SHIFL: Alpha-ketoglutarate permease (kgtP) from Shigella flexneri

KEGG orthology group: K03761, MFS transporter, MHS family, alpha-ketoglutarate permease (inferred from 99% identity to bph:Bphy_1226)

MetaCyc: 70% identical to alpha-ketoglutarate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-23

Predicted SEED Role

"dicarboxylic acid transporter PcaT" in subsystem Protocatechuate branch of beta-ketoadipate pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>QEN71_RS07390 MFS family transporter (Paraburkholderia sabiae LMG 24235)
MTDTTVFTPSDTRRRIFAIVGASSGNLVEWFDFYVYSFCALYFAPAFFPKGDTTAQLLNT
AGVFAAGFLMRPIGGWFFGRLADKRGRRFAMMVSVFMMCGGSLVIAALPTYAQIGALAPA
LLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLFALLVLVILQQ
VLTTEELKAWGWRVPFVVGALAALVALYLRRSLDETTTAETRQRKEAGTLRGMWKHKGAF
FTVLGFTAGGSLIFYTFTTYMQKYLVNTAGMNTKTASNVMTAALFVYMIMQPVFGALSDR
IGRRQSMLLFGFFATIGTVPLLHALKDVTSPVMAFVLVVIALAIVSFYTSISGLIKAEMF
PPEVRALGVGLSYAVANAIFGGSAEYVALWLKQAGSESMFYWYVTVLCAIAGLVSFRMRD
PSKEGYLRNEP