Protein Info for QEN71_RS07305 in Paraburkholderia sabiae LMG 24235

Annotation: saccharopine dehydrogenase NADP-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details transmembrane" amino acids 306 to 323 (18 residues), see Phobius details PF02737: 3HCDH_N" amino acids 2 to 42 (41 residues), 24.3 bits, see alignment 1.1e-08 PF03807: F420_oxidored" amino acids 2 to 59 (58 residues), 25.9 bits, see alignment E=5e-09 PF02254: TrkA_N" amino acids 3 to 75 (73 residues), 33.3 bits, see alignment E=2.2e-11 PF02558: ApbA" amino acids 3 to 51 (49 residues), 23.8 bits, see alignment 1.2e-08 PF03435: Sacchrp_dh_NADP" amino acids 3 to 112 (110 residues), 64.2 bits, see alignment E=6.1e-21 PF01370: Epimerase" amino acids 5 to 71 (67 residues), 21.3 bits, see alignment E=6.4e-08 PF13460: NAD_binding_10" amino acids 8 to 89 (82 residues), 27.6 bits, see alignment E=9.9e-10 PF16653: Sacchrp_dh_C" amino acids 120 to 341 (222 residues), 65.4 bits, see alignment E=3.7e-21

Best Hits

KEGG orthology group: None (inferred from 98% identity to bph:Bphy_1243)

Predicted SEED Role

"Carboxynorspermidine dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (365 amino acids)

>QEN71_RS07305 saccharopine dehydrogenase NADP-binding domain-containing protein (Paraburkholderia sabiae LMG 24235)
MKVAIVGAGLIGHTIAHMLRETGDYEVVAMDRDQHALDKLAAQGIPTRRVDSADAAALRA
EIQGFDALVNALPYYLAVSVASAAKGAGVHYFDLTEDVRATHAIRAIADSAEHAFMPQCG
LAPGFIGIAAHELANRFTEIRDVKMRVGALPEFPTNALKYNLTWSVDGLINEYCQPCEAI
RDSRTQWVQPLEGLEHFSLDGIEYEAFNTSGGLGTLCETLSGRVETLDYKSVRYPGHREL
MQFLLEDLRLATDRDTLKTIMRRSVPSTAQDVVLVFITVTGMRDGQLVQEVFTRKIFAKT
VCGVPMSAIQITTAGAMCAVLDLFREKKLPQSGFVRQEQVSLRDFLANRFGQLYEGRAME
ATATV