Protein Info for QEN71_RS07275 in Paraburkholderia sabiae LMG 24235

Annotation: YhfC family intramembrane metalloprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 42 to 61 (20 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 121 to 145 (25 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details amino acids 212 to 230 (19 residues), see Phobius details amino acids 236 to 257 (22 residues), see Phobius details PF10086: YhfC" amino acids 20 to 245 (226 residues), 283.5 bits, see alignment E=5.6e-89

Best Hits

KEGG orthology group: None (inferred from 86% identity to bph:Bphy_1249)

Predicted SEED Role

"Membrane protein DUF2324 in 2-Ketogluconate Utilization cluster"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (264 amino acids)

>QEN71_RS07275 YhfC family intramembrane metalloprotease (Paraburkholderia sabiae LMG 24235)
MSGLPVSPVTLAVLAAATIFVALLPIFLYRRWRAPFALNRRDAIAGIAVFALSAMLVERA
LNDYLLRQNPATSEWLSDPLAFVVYGALAAGICEEVGRFIAMRWLARRKTNDARDDGTAF
AYGLGHGGAEAWFVGVMVQAQWIAFGVLENRGQLDTYLGNLPAGPLMRIHLLLASLSPEM
AGVFVLERVAALVFQIGLSVLMWRGVRAGSRAILPIAIAAHALIDVPAAMSQAGMLPLVT
VDVIYAVAALAVAALLIRVHRRAA