Protein Info for QEN71_RS06410 in Paraburkholderia sabiae LMG 24235

Annotation: [protein-PII] uridylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 859 TIGR01693: protein-P-II uridylyltransferase" amino acids 27 to 850 (824 residues), 804 bits, see alignment E=9.2e-246 PF01909: NTP_transf_2" amino acids 65 to 93 (29 residues), 24.7 bits, see alignment (E = 6.2e-09) PF08335: GlnD_UR_UTase" amino acids 168 to 307 (140 residues), 152.9 bits, see alignment E=1.4e-48 PF01966: HD" amino acids 443 to 554 (112 residues), 35.6 bits, see alignment E=2.5e-12

Best Hits

Swiss-Prot: 86% identical to GLND_BURTA: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 97% identity to bph:Bphy_1340)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (859 amino acids)

>QEN71_RS06410 [protein-PII] uridylyltransferase (Paraburkholderia sabiae LMG 24235)
MSSVHAVAHSDATSLKADYKVAKTPLLDRFKTASNVDTLMHALARITDDALRGAWTACDL
PASLALLAVGGYGRGELAPHSDIDILVLLPDEPMPHLDARIERFIGLAWDLGLELGSSVR
TVSQCIEESANDVTVQTSLLEARRIVGSTTLFESFSLRYRDALDPRAFFQAKVLEMRQRH
AKFQDTPYSLEPNIKESPGGLRDLQLILWITQAAGFGSSWRELDARGLITDREARELRRN
EGFLKTLRARLHVLAGRRQDILVFDLQTPLAESFGFKATAARRASEQLMRRYYWAAKAVT
QLSTILIQNIEAQLFPSTSGITRVLSDRFVEKQGMLEIASDDVFEREPNAILEAFLLYEK
TPGIKGLSARTLRALYNARDKMDQRWRRDPENRHLFLEILKQPAGITHAMRLMNQTSVLG
RYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNMRRFAVAEHAHEYPFCSQLIANFERPY
VLYVAALFHDIAKGRGGDHSTLGMADARRFCRDHDISADDTALVVWLVQHHLTMSQVAQK
QDTSDPEVIKRFADLVGTERRLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRATLAVL
GGARPDAHSELKQRQEEALALLRLETVPENAHRALWDKLDVGYFLRHDAADIAWQTRVLY
RHVETETPIVRARPSPIGEALQVLVYVKDRPDLFAGICAYFDRNSLSVLDARVSTTRHGY
ALDNFLVAHTERDVHYRDIANLVEQELAERLRAEGTLLPEPSKGRLSRLSRTFPVTPRVD
LRADERGQYYILSVSANDRPGLLYSIARVLAEHRVGVHAARINTLGERVEDVFLLDGHGL
SDNRRQIQVETELLRAIAV